Block of granulocytic differentiation of 32Dcl3 cells by AML1/ETO(MTG8) but not by highly expressed Bcl-2.
about
Nuclear import and subnuclear localization of the proto-oncoprotein ETO (MTG8)A distinct epigenetic signature at targets of a leukemia protein.BCL-2 cooperates with promyelocytic leukemia retinoic acid receptor alpha chimeric protein (PMLRARalpha) to block neutrophil differentiation and initiate acute leukemia.Dichotomy of AML1-ETO functions: growth arrest versus block of differentiationA proposal for clinical genetics (genetics in medicine) education for medical technologists and other health professionals in Japan.Multiple subnuclear targeting signals of the leukemia-related AML1/ETO and ETO repressor proteins.AML1 and the AML1-ETO fusion protein in the pathogenesis of t(8;21) AML.Common themes in the pathogenesis of acute myeloid leukemia.Estrogen-regulated conditional oncoproteins: tools to address open questions in normal myeloid cell function, normal myeloid differentiation, and the genetic basis of differentiation arrest in myeloid leukemia.The p21Waf1 pathway is involved in blocking leukemogenesis by the t(8;21) fusion protein AML1-ETO.A role for RUNX1 in hematopoiesis and myeloid leukemia.Multi-sites cleavage of leukemogenic AML1-ETO fusion protein by caspase-3 and its contribution to increased apoptotic sensitivity.Myeloid maturation block by AML1-MTG16 is associated with Csf1r epigenetic downregulation.Desferrioxamine induces leukemic cell differentiation potentially by hypoxia-inducible factor-1 alpha that augments transcriptional activity of CCAAT/enhancer-binding protein-alpha.Williams-Beuren syndrome critical region-5/non-T-cell activation linker: a novel target gene of AML1/ETO.The fusion protein AML1-ETO in acute myeloid leukemia with translocation t(8;21) induces c-jun protein expression via the proximal AP-1 site of the c-jun promoter in an indirect, JNK-dependent manner.
P2860
Q28144264-42AA9BDF-F55D-443A-9E9C-F11FFD9796F8Q33271210-5390EC7E-06CB-4DD2-9817-EE5364712694Q33335885-F53E5850-905B-4861-A87B-FC2F7026D4A3Q33969245-E37B73A7-0D69-4E0E-B745-EEA96668287FQ34081370-A736CDD0-1B7B-42BD-9D00-DF356F91C49FQ34386755-EEFD89E8-4C60-4083-B145-D87B8E238C10Q34405452-C5807707-CC4F-4F04-9CA6-293ABEC78258Q34405458-2550BB8F-BF89-4F8C-8282-F91CB1A5F0D5Q35198920-D901F256-A5D5-4837-A7D2-0588D9D5FB45Q35828623-87650AC1-3BBF-45C4-A1C7-7D5C7B505707Q38101285-5FD9B451-CEFC-4BC3-95BC-819019D61F11Q40054881-8724240A-784F-4235-9BCC-0CDE2052385EQ40399336-B6582DA4-9E93-42BF-A51B-F65DA29AF591Q40420598-9D889BCF-858E-4DE9-847A-2DAB0E7CC970Q40503129-A5D9FE3C-6CAD-4850-B1DC-53073E7D4511Q47659569-32CB182B-1935-4149-AB93-2F4410D9666D
P2860
Block of granulocytic differentiation of 32Dcl3 cells by AML1/ETO(MTG8) but not by highly expressed Bcl-2.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
Block of granulocytic differen ...... not by highly expressed Bcl-2.
@en
type
label
Block of granulocytic differen ...... not by highly expressed Bcl-2.
@en
prefLabel
Block of granulocytic differen ...... not by highly expressed Bcl-2.
@en
P2093
P2860
P356
P1433
P1476
Block of granulocytic differen ...... not by highly expressed Bcl-2.
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.ONC.1202735
P407
P577
1999-07-01T00:00:00Z
P5875
P6179
1024659549