The fusion protein AML1-ETO in acute myeloid leukemia with translocation t(8;21) induces c-jun protein expression via the proximal AP-1 site of the c-jun promoter in an indirect, JNK-dependent manner.

The fusion protein AML1-ETO in acute myeloid leukemia with translocation t(8;21) induces c-jun protein expression via the proximal AP-1 site of the c-jun promoter in an indirect, JNK-dependent manner.

Item
http://www.wikidata.org/entity/Q47659569
AML1-ETO and C-KIT mutation/overexpression in t(8;21) leukemia: implication in stepwise leukemogenesis and response to Gleevec.Elevated PIN1 expression by C/EBPalpha-p30 blocks C/EBPalpha-induced granulocytic differentiation through c-Jun in AMLThe p21Waf1 pathway is involved in blocking leukemogenesis by the t(8;21) fusion protein AML1-ETO.Role of the proteasome in modulating native G-CSFR expression.MAPK signaling pathways in the regulation of hematopoiesis.JUN is a key transcriptional regulator of the unfolded protein response in acute myeloid leukemia.The c-Jun-N-terminal-Kinase inhibitor SP600125 enhances the butyrate derivative D1-induced apoptosis via caspase 8 activation in Kasumi 1 t(8;21) acute myeloid leukaemia cells.Synergistic suppression of t(8;21)-positive leukemia cell growth by combining oridonin and MAPK1/ERK2 inhibitors.Commonly dysregulated genes in murine APL cells.Suppression of RUNX1/ETO oncogenic activity by a small molecule inhibitor of tetramerization.AML1/ETO trans-activates c-KIT expression through the long range interaction between promoter and intronic enhancer.RUNX1-ETO Leukemia.The Oncogenic Transcription Factor RUNX1/ETO Corrupts Cell Cycle Regulation to Drive Leukemic Transformation
P2860

The fusion protein AML1-ETO in acute myeloid leukemia with translocation t(8;21) induces c-jun protein expression via the proximal AP-1 site of the c-jun promoter in an indirect, JNK-dependent manner.

Item
http://www.wikidata.org/entity/Q47659569
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name
The fusion protein AML1-ETO in ...... ndirect, JNK-dependent manner.
@en
The fusion protein AML1-ETO in ...... ndirect, JNK-dependent manner.
@nl
type
label
The fusion protein AML1-ETO in ...... ndirect, JNK-dependent manner.
@en
The fusion protein AML1-ETO in ...... ndirect, JNK-dependent manner.
@nl
prefLabel
The fusion protein AML1-ETO in ...... ndirect, JNK-dependent manner.
@en
The fusion protein AML1-ETO in ...... ndirect, JNK-dependent manner.
@nl
P1433
P1476
P2093
P2860
P2888
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P921
P356
P1433
P1476
The fusion protein AML1-ETO in ...... ndirect, JNK-dependent manner.
@en
P2093
P2860
P2888
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P921