BCL-2 cooperates with promyelocytic leukemia retinoic acid receptor alpha chimeric protein (PMLRARalpha) to block neutrophil differentiation and initiate acute leukemia.
about
Deletion of Bid impedes cell proliferation and hepatic carcinogenesisIn vivo activation of cAMP signaling induces growth arrest and differentiation in acute promyelocytic leukemia.Identification of a myeloid committed progenitor as the cancer-initiating cell in acute promyelocytic leukemia.Reduced PU.1 expression causes myeloid progenitor expansion and increased leukemia penetrance in mice expressing PML-RARalpha.Prospective isolation of human clonogenic common myeloid progenitors.A protease-resistant PML-RAR{alpha} has increased leukemogenic potential in a murine model of acute promyelocytic leukemiaIn vivo analysis of the molecular genetics of acute promyelocytic leukemia.Normal and leukemic hematopoiesis: are leukemias a stem cell disorder or a reacquisition of stem cell characteristics?Cell cycle arrest and apoptotic cell death in cultured human gastric carcinoma cells mediated by arsenic trioxide.Sequencing a mouse acute promyelocytic leukemia genome reveals genetic events relevant for disease progressionDisruption of differentiation in human cancer: AML shows the way.Cooperation of cytokine signaling with chimeric transcription factors in leukemogenesis: PML-retinoic acid receptor alpha blocks growth factor-mediated differentiation.The Bcl-2 family: roles in cell survival and oncogenesis.Acute promyelocytic leukemia: where does it stem from?Acute promyelocytic leukemia: PML/RARalpha and the leukemic stem cell.Insertional mutagenesis identifies genes that promote the immortalization of primary bone marrow progenitor cellsConcepts of human leukemic development.Animal models of acute myelogenous leukaemia - development, application and future perspectives.The significance of low PU.1 expression in patients with acute promyelocytic leukemia.Gatekeeper pathways and cellular background in the pathogenesis and therapy of AML.Inhibition of apoptosis by BCL2 prevents leukemic transformation of a murine myelodysplastic syndromeAcute promyelocytic leukemia: a model of molecular target based therapy.Role of promyelocytic leukemia (PML) protein in tumor suppressionBCL-xL/MCL-1 inhibition and RARγ antagonism work cooperatively in human HL60 leukemia cells.Treatment of acute promyelocytic leukaemia with all-trans retinoic acid and arsenic trioxide: a paradigm of synergistic molecular targeting therapy.Cancer stem cells: a review.Quantitative trait loci associated with susceptibility to therapy-related acute murine promyelocytic leukemia in hCG-PML/RARA transgenic miceHematopoietic developmental pathways: on cellular basis.Review: genetic models of acute myeloid leukaemia.Transcription and methylation analyses of preleukemic promyelocytes indicate a dual role for PML/RARA in leukemia initiation.Impairment of p53 acetylation, stability and function by an oncogenic transcription factor.Notch signaling in acute promyelocytic leukemiaFLT3-ITD up-regulates MCL-1 to promote survival of stem cells in acute myeloid leukemia via FLT3-ITD-specific STAT5 activation.Expression profiling of murine acute promyelocytic leukemia cells reveals multiple model-dependent progression signatures.Hepatocyte-specific Bid depletion reduces tumor development by suppressing inflammation-related compensatory proliferationmiR-125b regulates cell progression in chronic myeloid leukemia via targeting BAK1Tumor-initiating stem-like cells and drug resistance: carcinogenesis through Toll-like receptors, environmental factors, and virus.Genetic reduction of class IA PI-3 kinase activity alters fetal hematopoiesis and competitive repopulating ability of hematopoietic stem cells in vivo.Oncogenic K-ras cooperates with PML-RAR alpha to induce an acute promyelocytic leukemia-like disease.Evidence of functional interaction between NuMA-RARalpha and RXRalpha in an in vivo model of acute promyelocytic leukemia.
P2860
Q28507399-1446BF04-7A91-4401-976D-3ADEC426931FQ33185196-482D6D4A-48B8-490C-AE4E-B60453E50F00Q33560404-8967E828-114B-4390-9932-0B3DA43C3F9DQ33920326-4FF82FE4-4C35-406F-8D9C-1D08793255DFQ34154606-7A295758-30C9-497F-B9AF-D524AA017ACBQ34310547-1FF542D9-E056-413C-A372-EA9206454B65Q34405484-99A80340-BC8F-4090-AE93-D6065A303CDCQ34542144-ED5FEB1D-24D2-4ED7-BA1F-7542341E95A7Q34558420-4349378F-F570-43F9-808F-0D3A14977E63Q34755408-9C419B29-A392-490D-BBE0-704866562CBAQ35058575-3ABA7AAF-7012-4CAB-B7DB-DBEBBD999FBEQ35150597-DBD42743-22AB-408C-8740-20CE7A956E21Q35591695-0DCA3A52-442D-4B5F-B5AC-25A6B2BD6087Q35635316-830BB80E-240F-452A-A4DB-E67BCC12A619Q35753735-669F105E-3AE1-4C0B-89EF-C38A49966CF1Q35847760-20612872-6606-498A-8CBE-0DF9D150A479Q35892080-6989CC6A-E708-4617-ACDD-56A30ADAC6F4Q36066980-005314E2-2AC0-4179-B6F0-473FC5EB9456Q36125630-2D789A09-5124-4EED-B8BD-65A7FC81CB6DQ36233848-18115358-EDA6-4373-80F4-027EFDE71A9AQ36250937-E9149693-BFFA-48F4-BF87-17DAA4EA89DFQ36270144-B796D3A0-C0E1-46CB-8C0C-A3A0BAFD3A92Q36376155-295774C5-F290-4B1E-B460-366F07763501Q36504936-5193305C-A3DD-4C32-AFBD-698BC0F5F981Q36732473-9FD501E5-EE78-4C82-AECA-BC5ABC3198F6Q36821443-4568543F-3C8B-4D2C-86B3-C5561AA515A6Q36835079-DC60583B-1AD3-4AC2-A0AC-BDEEFC3D9E9DQ36970175-BD0DB922-0D0B-4678-8F69-0BAD173F2398Q37080843-6CC04840-EAB5-46AD-8B9F-6723CB741758Q37216371-C1FA83A9-F2C4-48E1-B266-C4DC71613D13Q37258978-A9A45632-5155-424E-B494-337F76AE8287Q37414175-7689641B-AA2B-4B8E-9AE0-97074B207371Q37460343-477CC212-2D5E-4E20-8A5E-80ADAA8C9729Q37683754-94CB2B79-574D-4BAC-9097-F42FD92AF96FQ39743133-4F313380-CB04-46EC-8FF9-75F626955F56Q40683422-2B3663C6-2AE3-4C87-A8F8-A8A59B69427FQ41196091-64CAC452-7AD7-444B-876E-456790BB8CFDQ41834449-C34D8BBD-5BE7-4AEA-A15D-6D347D50FC7CQ42082533-689E1D25-86BF-46A7-A1AC-35404B811886Q42814510-341E3031-28FF-4343-8F7D-B02D16661A5D
P2860
BCL-2 cooperates with promyelocytic leukemia retinoic acid receptor alpha chimeric protein (PMLRARalpha) to block neutrophil differentiation and initiate acute leukemia.
description
2001 nî lūn-bûn
@nan
2001 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
BCL-2 cooperates with promyelo ...... n and initiate acute leukemia.
@ast
BCL-2 cooperates with promyelo ...... n and initiate acute leukemia.
@en
BCL-2 cooperates with promyelo ...... eceptor alpha chimeric protein
@nl
type
label
BCL-2 cooperates with promyelo ...... n and initiate acute leukemia.
@ast
BCL-2 cooperates with promyelo ...... n and initiate acute leukemia.
@en
BCL-2 cooperates with promyelo ...... eceptor alpha chimeric protein
@nl
prefLabel
BCL-2 cooperates with promyelo ...... n and initiate acute leukemia.
@ast
BCL-2 cooperates with promyelo ...... n and initiate acute leukemia.
@en
BCL-2 cooperates with promyelo ...... eceptor alpha chimeric protein
@nl
P2093
P2860
P356
P1476
BCL-2 cooperates with promyelo ...... n and initiate acute leukemia.
@en
P2093
B T Truong
D B Shultz
I L Weissman
J M Bishop
M C Guillemin
V Lallemand-Breitenbach
P2860
P304
P356
10.1084/JEM.193.4.531
P407
P577
2001-02-01T00:00:00Z