Structure enabled design of BAZ2-ICR, a chemical probe targeting the bromodomains of BAZ2A and BAZ2B.
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NMR Fragment Screening Hit Induces Plasticity of BRD7/9 BromodomainsDiscovery and Optimization of a Selective Ligand for the Switch/Sucrose Nonfermenting-Related Bromodomains of Polybromo Protein-1 by the Use of Virtual Screening and Hydration AnalysisDual Screening of BPTF and Brd4 Using Protein-Observed Fluorine NMR Uncovers New Bromodomain Probe MoleculesEpigenetic stress responses induce muscle stem-cell ageing by Hoxa9 developmental signals.Structure-Based Identification of Inhibitory Fragments Targeting the p300/CBP-Associated Factor Bromodomain.Structure-Guided Design of IACS-9571, a Selective High-Affinity Dual TRIM24-BRPF1 Bromodomain Inhibitor.Selective targeting of Bromodomains of the Bromodomain-PHD Fingers family impairs osteoclast differentiation.Discovery of a Chemical Tool Inhibitor Targeting the Bromodomains of TRIM24 and BRPF.Discovery and Characterization of GSK2801, a Selective Chemical Probe for the Bromodomains BAZ2A and BAZ2B.Progress in the Development of non-BET Bromodomain Chemical Probes.Epigenomic regulation of oncogenesis by chromatin remodeling.Selective targeting of epigenetic reader domains.Bromodomains in Protozoan Parasites: Evolution, Function, and Opportunities for Drug Development.Selectivity on-target of bromodomain chemical probes by structure-guided medicinal chemistry and chemical biology.Bromodomain inhibitors and cancer therapy: From structures to applications.Chemical modulators for epigenome reader domains as emerging epigenetic therapies for cancer and inflammation.Protein dynamics and structural waters in bromodomains.Chemical probes and inhibitors of bromodomains outside the BET family.Predicted Biological Activity of Purchasable Chemical Space.Antitubercular activity of 1,2,3-triazolyl fatty acid derivatives.Targeting Ligandable Pockets on Plant Homeodomain (PHD) Zinc Finger Domains by a Fragment-Based Approach.A poised fragment library enables rapid synthetic expansion yielding the first reported inhibitors of PHIP(2), an atypical bromodomain† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c5sc03115j.
P2860
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P2860
Structure enabled design of BAZ2-ICR, a chemical probe targeting the bromodomains of BAZ2A and BAZ2B.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
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2015年论文
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name
Structure enabled design of BA ...... omodomains of BAZ2A and BAZ2B.
@en
type
label
Structure enabled design of BA ...... omodomains of BAZ2A and BAZ2B.
@en
prefLabel
Structure enabled design of BA ...... omodomains of BAZ2A and BAZ2B.
@en
P2093
P2860
P50
P356
P1476
Structure enabled design of BA ...... omodomains of BAZ2A and BAZ2B.
@en
P2093
Angela Hayes
Catherine Rogers
Cynthia Tallant
Ludovic Drouin
Manjuan Liu
Martin Philpott
Octovia Monteiro
Oleg Fedorov
Sally McGrath
Swen Hoelder
P2860
P304
P356
10.1021/JM501963E
P407
P577
2015-02-26T00:00:00Z