Exendin-(9-39) is an inverse agonist of the murine glucagon-like peptide-1 receptor: implications for basal intracellular cyclic adenosine 3',5'-monophosphate levels and beta-cell glucose competence.
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Physiology of proglucagon peptides: role of glucagon and GLP-1 in health and diseaseGlucagon-Like Peptide-1 and Its Class B G Protein-Coupled Receptors: A Long March to Therapeutic SuccessesMolecular Characterisation of Small Molecule Agonists Effect on the Human Glucagon Like Peptide-1 Receptor InternalisationOver-expression of the glucagon-like peptide-1 receptor on INS-1 cells confers autocrine stimulation of insulin gene promoter activity: a strategy for production of pancreatic beta-cell lines for use in transplantationBrain GLP-1 signaling regulates femoral artery blood flow and insulin sensitivity through hypothalamic PKC-δIncretin-modulated beta cell energetics in intact islets of Langerhans.Effect of endogenous GLP-1 on insulin secretion in type 2 diabetes.Inverse agonism at G protein-coupled receptors: (patho)physiological relevance and implications for drug discovery.Endogenous glucagon-like peptide-1 reduces drinking behavior and is differentially engaged by water and food intakes in rats.Postprandial insulin secretion after gastric bypass surgery: the role of glucagon-like peptide 1.Gluco-incretins regulate beta-cell glucose competence by epigenetic silencing of Fxyd3 expressionJejunal linoleic acid infusions require GLP-1 receptor signaling to inhibit food intake: implications for the effectiveness of Roux-en-Y gastric bypass.Glucagon-like peptide 1: evolution of an incretin into a treatment for diabetes.GLP-1 receptor antagonist exendin-(9-39) elevates fasting blood glucose levels in congenital hyperinsulinism owing to inactivating mutations in the ATP-sensitive K+ channelProstaglandin E2 receptor, EP3, is induced in diabetic islets and negatively regulates glucose- and hormone-stimulated insulin secretion.Hyperphagia and increased fat accumulation in two models of chronic CNS glucagon-like peptide-1 loss of function.Exaggerated glucagon-like peptide 1 response is important for improved β-cell function and glucose tolerance after Roux-en-Y gastric bypass in patients with type 2 diabetes.GLP-1 and energy balance: an integrated model of short-term and long-term controlThe structure and function of the glucagon-like peptide-1 receptor and its ligandsExendin-(9-39) corrects fasting hypoglycemia in SUR-1-/- mice by lowering cAMP in pancreatic beta-cells and inhibiting insulin secretion.A model for receptor-peptide binding at the glucagon-like peptide-1 (GLP-1) receptor through the analysis of truncated ligands and receptors.The glucagon-like peptide-1 receptor binding site for the N-terminus of GLP-1 requires polarity at Asp198 rather than negative charge.Genes induced by growth arrest in a pancreatic beta cell line: identification by analysis of cDNA arrays.Regulation of Na+/H+ exchanger NHE3 by glucagon-like peptide 1 receptor agonist exendin-4 in renal proximal tubule cells.The positive charge at Lys-288 of the glucagon-like peptide-1 (GLP-1) receptor is important for binding the N-terminus of peptide agonists.Grape powder attenuates the negative effects of GLP-1 receptor antagonism by exendin-3 (9-39) in a normoglycemic mouse model.New Antihyperglycemic Drugs and Heart Failure: Synopsis of Basic and Clinical Data.Discovery, characterization, and clinical development of the glucagon-like peptides.Equine glucagon-like peptide-1 receptor physiology.The Role of Pancreatic Preproglucagon in Glucose Homeostasis in Mice.
P2860
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P2860
Exendin-(9-39) is an inverse agonist of the murine glucagon-like peptide-1 receptor: implications for basal intracellular cyclic adenosine 3',5'-monophosphate levels and beta-cell glucose competence.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Exendin-(9-39) is an inverse a ...... beta-cell glucose competence.
@en
type
label
Exendin-(9-39) is an inverse a ...... beta-cell glucose competence.
@en
prefLabel
Exendin-(9-39) is an inverse a ...... beta-cell glucose competence.
@en
P2093
P356
P1433
P1476
Exendin-(9-39) is an inverse a ...... beta-cell glucose competence.
@en
P2093
E Schaerer
L Scrocchi
P304
P356
10.1210/ENDO.139.11.6295
P407
P577
1998-11-01T00:00:00Z