Double-strand break repair by Ku70 requires heterodimerization with Ku80 and DNA binding functions.
about
Enhancer activation requires trans-recruitment of a mega transcription factor complexMapping of protein-protein interactions within the DNA-dependent protein kinase complexThe C terminus of Ku80 activates the DNA-dependent protein kinase catalytic subunitMouse embryonic stem cells, but not somatic cells, predominantly use homologous recombination to repair double-strand DNA breaksHuman securin, hPTTG, is associated with Ku heterodimer, the regulatory subunit of the DNA-dependent protein kinaseRadio-resistant mesenchymal stem cells: mechanisms of resistance and potential implications for the clinicA short C-terminal domain of Yku70p is essential for telomere maintenance.Heat shock factor 1, an inhibitor of non-homologous end joining repairUp-regulation of DNA-dependent protein kinase correlates with radiation resistance in oral squamous cell carcinomaMolecular mode of action and role of TP53 in the sensitivity to the novel epothilone sagopilone (ZK-EPO) in A549 non-small cell lung cancer cellsInteraction of Ku protein and DNA-dependent protein kinase catalytic subunit with nucleic acidsHsp90 protein interacts with phosphorothioate oligonucleotides containing hydrophobic 2'-modifications and enhances antisense activityRequirements for the nucleolytic processing of DNA ends by the Werner syndrome protein-Ku70/80 complex.Dysbindin-1, a schizophrenia-related protein, functionally interacts with the DNA- dependent protein kinase complex in an isoform-dependent manner.Mutant huntingtin impairs Ku70-mediated DNA repair.HP1alpha recruitment to DNA damage by p150CAF-1 promotes homologous recombination repair.DNA damage-dependent nuclear dynamics of the Mre11 complexVisualization of inositol phosphate-dependent mobility of Ku: depletion of the DNA-PK cofactor InsP6 inhibits Ku mobility.Subcellular proteomics reveals a role for nucleo-cytoplasmic trafficking at the DNA replication origin activation checkpointThe actin depolymerizing factor (ADF)/cofilin signaling pathway and DNA damage responses in cancerDNA end binding activity and Ku70/80 heterodimer expression in human colorectal tumor.Interaction of a cyclin E fragment with Ku70 regulates Bax-mediated apoptosis.The life and death of DNA-PK.Expression of the Ku70 subunit (XRCC6) and protection from low dose ionizing radiation during zebrafish embryogenesis.Cloning, localization and focus formation at DNA damage sites of canine Ku70.PTTG: an important target gene for ovarian cancer therapy.A nonhomologous end-joining pathway is required for protein phosphatase 2A promotion of DNA double-strand break repair.The DNA-PK catalytic subunit regulates Bax-mediated excitotoxic cell death by Ku70 phosphorylation.Temporal proteomic profiling of Chlamydia trachomatis-infected HeLa-229 human cervical epithelial cells.Identification and characterization of intracellular proteins that bind oligonucleotides with phosphorothioate linkages.Ku antigen-DNA conformation determines the activation of DNA-dependent protein kinase and DNA sequence-directed repression of mouse mammary tumor virus transcription.Sequence-specific binding of Ku autoantigen to single-stranded DNA.Landscape of the SOX2 protein-protein interactome.Host Proteins Ku and HMGA1 As Participants of HIV-1 Transcription.Ubiquitylation of Ku80 by RNF126 Promotes Completion of Nonhomologous End Joining-Mediated DNA RepairCisplatin-DNA adducts inhibit translocation of the Ku subunits of DNA-PK.Hdm2 is a ubiquitin ligase of Ku70-Akt promotes cell survival by inhibiting Hdm2-dependent Ku70 destabilization.Response to multiple radiation doses of fibroblasts over-expressing dominant negative Ku70.Arsenite-induced alterations in Ku70-deficient cells: a model to study genotoxic effects.Identification of cellular factors associated with the 3'-nontranslated region of the hepatitis C virus genome.
P2860
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P2860
Double-strand break repair by Ku70 requires heterodimerization with Ku80 and DNA binding functions.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Double-strand break repair by ...... u80 and DNA binding functions.
@en
type
label
Double-strand break repair by ...... u80 and DNA binding functions.
@en
prefLabel
Double-strand break repair by ...... u80 and DNA binding functions.
@en
P2860
P356
P1433
P1476
Double-strand break repair by ...... u80 and DNA binding functions.
@en
P2093
P2860
P304
P356
10.1093/EMBOJ/16.22.6874
P407
P577
1997-11-01T00:00:00Z