Conditional mutator phenotypes in hMSH2-deficient tumor cell lines.
about
Induction of microsatellite instability by oxidative DNA damageGenome-wide mutation avalanches induced in diploid yeast cells by a base analog or an APOBEC deaminaseA cancer-associated DNA polymerase delta variant modeled in yeast causes a catastrophic increase in genomic instability.Mechanisms of genome-wide hypermutation in stationary phase.Significance of multiple mutations in cancer.Clusters of mutations from transient hypermutabilityBase excision repair in a network of defence and tolerance.Hypermutability in carcinogenesisAdaptive mutation: has the unicorn landed?Functional overlap in mismatch repair by human MSH3 and MSH6.Some features of the mutability of bacteria during nonlethal selectionMutator phenotypes of yeast strains heterozygous for mutations in the MSH2 gene.Negative regulation of mutS and mutH repair gene expression by the Hfq and RpoS global regulators of Escherichia coli K-12.Tumors of DNA mismatch repair-deficient hosts exhibit dramatic increases in genomic instability.The role of SOS and flap processing in microsatellite instability in Escherichia coli.Aspirin suppresses the mutator phenotype associated with hereditary nonpolyposis colorectal cancer by genetic selection.Strand asymmetry of CpG transitions as indicator of G1 phase-dependent origin of multiple tumorigenic p53 mutations in stem cells.Extensive molecular screening for hereditary non-polyposis colorectal cancerVariation in RNA expression and genomic DNA content acquired during cell culture.The cellular ecology of progressive neoplastic transformation: a clonal analysis.Contribution of the mismatch DNA repair system to the generation of stationary-phase-induced mutants of Bacillus subtilis.Confluence-induced alterations in CpG island methylation in cultured normal human fibroblasts.Mutator phenotype of mammalian cells due to deficiency of NEIL1 DNA glycosylase, an oxidized base-specific repair enzyme.Mutation and cancer: the antecedents to our studies of adaptive mutation.Some recollections and reflections on mutation rates.Replication errors: cha(lle)nging the genome.Enrichment for DNA mismatch repair-deficient cells during treatment with cisplatin.Hereditary stability and variation in evolution and development.
P2860
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P2860
Conditional mutator phenotypes in hMSH2-deficient tumor cell lines.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Conditional mutator phenotypes in hMSH2-deficient tumor cell lines.
@en
type
label
Conditional mutator phenotypes in hMSH2-deficient tumor cell lines.
@en
prefLabel
Conditional mutator phenotypes in hMSH2-deficient tumor cell lines.
@en
P2093
P1433
P1476
Conditional mutator phenotypes in hMSH2-deficient tumor cell lines.
@en
P2093
P304
P356
10.1126/SCIENCE.277.5331.1523
P407
P577
1997-09-01T00:00:00Z