about
Cancer as an evolutionary and ecological processCancer is a preventable disease that requires major lifestyle changesHomologous Recombination and Its Role in CarcinogenesisStructure and potential mutagenicity of new hydantoin products from guanosine and 8-oxo-7,8-dihydroguanine oxidation by transition metals.Bacteria in Cancer Therapy: Renaissance of an Old ConceptEffects of the lifestyle habits in breast cancer transcriptional regulationTissue Regeneration in the Chronically Inflamed Tumor Environment: Implications for Cell Fusion Driven Tumor Progression and Therapy Resistant Tumor Hybrid CellsThe significance of genetics for cholangiocarcinoma developmentPrecision targeted therapy of ovarian cancerInvestigation of the substrate spectrum of the human mismatch-specific DNA N-glycosylase MED1 (MBD4): fundamental role of the catalytic domainBiphasic kinetics of the human DNA repair protein MED1 (MBD4), a mismatch-specific DNA N-glycosylaseLife, death, and tax: role of HTLV-I oncoprotein in genetic instability and cellular transformationMismatch repair proteins hMLH1 and hMSH2 are differently expressed in the three main subtypes of sporadic renal cell carcinomaA mathematical model of cancer stem cell driven tumor initiation: implications of niche size and loss of homeostatic regulatory mechanismsA Physical Mechanism and Global Quantification of Breast CancerLinking DNA adduct formation and human cancer risk in chemical carcinogenesis.Application of inter-simple sequence repeat PCR to mouse models: assessment of genetic alterations in carcinogenesis.Integration of somatic mutation, expression and functional data reveals potential driver genes predictive of breast cancer survival.Multilineage progression of genetically unstable tumor subclones in cutaneous T-cell lymphoma.Evidence of genetic instability in tumors and normal nearby tissues.Human cancers express mutator phenotypes: origin, consequences and targeting.The optimal rate of chromosome loss for the inactivation of tumor suppressor genes in cancer.Metastatic triple-negative breast cancer patient with TP53 tumor mutation experienced 11 months progression-free survival on bortezomib monotherapy without adverse events after ending standard treatments with grade 3 adverse events.Racial disparity in metabolic regulation of cancer.Role of MED1 (MBD4) Gene in DNA repair and human cancer.Multiple mutations and cancer.Multistage carcinogenesis and the incidence of colorectal cancer.DNA double strand break repair and chromosomal translocation: lessons from animal models.Abnormality of the DNA double-strand-break checkpoint/repair genes, ATM, BRCA1 and TP53, in breast cancer is related to tumour gradeQuantitative analysis of mitotic Olig2 cells in adult human brain and gliomas: implications for glioma histogenesis and biologyRat Pig-a mutation assay responds to the genotoxic carcinogen ethyl carbamate but not the non-genotoxic carcinogen methyl carbamate.Allelic losses at genomic instability-associated loci in villous adenomas and adjacent colorectal cancers.Genetic alterations of hepatocellular carcinoma by random amplified polymorphic DNA analysis and cloning sequencing of tumor differential DNA fragment.Chromosomal rearrangement as the basis for human tumourigenesis.Attenuation of DNA polymerase beta-dependent base excision repair and increased DMS-induced mutagenicity in aged mice.A distinct and replicable variant of the squamous cell carcinoma gene inositol polyphosphate-5-phosphatase modifies the susceptibility of arsenic-associated skin lesions in Bangladesh.Small-molecule binding of the axin RGS domain promotes β-catenin and Ras degradation.Liver cell adenoma and liver cell adenomatosis.Cancer cell growth and survival as a system-level property sustained by enhanced glycolysis and mitochondrial metabolic remodelingDeregulation of cyclin E in human cells interferes with prereplication complex assembly.
P2860
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P2860
description
2000 nî lūn-bûn
@nan
2000 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի մարտին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Significance of multiple mutations in cancer.
@ast
Significance of multiple mutations in cancer.
@en
type
label
Significance of multiple mutations in cancer.
@ast
Significance of multiple mutations in cancer.
@en
prefLabel
Significance of multiple mutations in cancer.
@ast
Significance of multiple mutations in cancer.
@en
P2860
P356
P1433
P1476
Significance of multiple mutations in cancer.
@en
P2860
P304
P356
10.1093/CARCIN/21.3.379
P407
P577
2000-03-01T00:00:00Z