Phosphatidylcholine and phosphatidylethanolamine behave as substrates of the human MDR1 P-glycoprotein.
about
Structure of P-glycoprotein reveals a molecular basis for poly-specific drug bindingMammalian P4-ATPases and ABC transporters and their role in phospholipid transportMolecular properties of bacterial multidrug transportersRegulation of cholesterol homeostasis in macrophages and consequences for atherosclerotic lesion developmentMultidrug-resistance P-glycoprotein (MDR1) secretes platelet-activating factorNBD-labeled phosphatidylcholine and phosphatidylethanolamine are internalized by transbilayer transport across the yeast plasma membrane.P-glycoprotein (ABCB1) interacts directly with lipid-based anti-cancer drugs and platelet-activating factors.Membrane phospholipid redistribution in cancer micro-particles and implications in the recruitment of cationic protein factors.The multidrug transporter, P-glycoprotein, actively mediates cholesterol redistribution in the cell membrane.P-glycoprotein in acute myeloid leukaemia: therapeutic implications of its association with both a multidrug-resistant and an apoptosis-resistant phenotype.Lipid traffic: the ABC of transbilayer movement.Regulation of transbilayer plasma membrane phospholipid asymmetry.ABC multidrug transporters: structure, function and role in chemoresistance.Chemical control of phospholipid distribution across bilayer membranes.Schistosome ABC multidrug transporters: From pharmacology to physiology.The ABC transporters MDR1 and MRP2: multiple functions in disposition of xenobiotics and drug resistance.Novel understanding of ABC transporters ABCB1/MDR/P-glycoprotein, ABCC2/MRP2, and ABCG2/BCRP in colorectal pathophysiologyP-glycoprotein structure and evolutionary homologies.Endocrine and metabolic regulation of renal drug transporters.Computer simulations of ABC transporter components.Improving nucleoside analogs via lipid conjugation: Is fatter any better?On the origin of large flexibility of P-glycoprotein in the inward-facing stateABC multidrug transporters in schistosomes and other parasitic flatwormsNanomicellar paclitaxel increases cytotoxicity of multidrug resistant breast cancer cellsPhosphatidylethanolamine is externalized at the surface of microparticles.Complex Interplay between the P-Glycoprotein Multidrug Efflux Pump and the Membrane: Its Role in Modulating Protein Function.Lipid transport by mammalian ABC proteins.Regulation of metabolism and transport of sphingosine-1-phosphate in mammalian cells.Nanoparticle delivery of anticancer drugs overcomes multidrug resistance in breast cancer.Alkyl-lysophospholipid resistance in multidrug-resistant Leishmania tropica and chemosensitization by a novel P-glycoprotein-like transporter modulatorLiposome composition is important for retention of liposomal rhodamine in P-glycoprotein-overexpressing cancer cells.Verapamil induces upregulation of P-glycoprotein expression on human monocyte derived dendritic cells.Effects of monensin liposomes on the cytotoxicity, apoptosis and expression of multidrug resistance genes in doxorubicin-resistant human breast tumour (MCF-7/dox) cell-line.Natural phosphatidylcholine is actively translocated across the plasma membrane to the surface of mammalian cells.Enhanced exposure of phosphatidylserine in human gastric carcinoma cells overexpressing the half-size ABC transporter BCRP (ABCG2).Transport of phosphatidylserine via MDR1 (multidrug resistance 1)P-glycoprotein in a human gastric carcinoma cell line.Conformational changes of P-glycoprotein by nucleotide binding.Structural recognition of tubulysin B derivatives by multidrug resistance efflux transporters in human cancer cells.The reconstituted P-glycoprotein multidrug transporter is a flippase for glucosylceramide and other simple glycosphingolipids.Multidrug resistance (MDR1) P-glycoprotein enhances esterification of plasma membrane cholesterol.
P2860
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P2860
Phosphatidylcholine and phosphatidylethanolamine behave as substrates of the human MDR1 P-glycoprotein.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Phosphatidylcholine and phosph ...... the human MDR1 P-glycoprotein.
@en
type
label
Phosphatidylcholine and phosph ...... the human MDR1 P-glycoprotein.
@en
prefLabel
Phosphatidylcholine and phosph ...... the human MDR1 P-glycoprotein.
@en
P2093
P356
P1433
P1476
Phosphatidylcholine and phosph ...... the human MDR1 P-glycoprotein.
@en
P2093
Dunussi-Joannopoulos K
Furlong ST
P304
P356
10.1021/BI962728R
P407
P577
1997-05-01T00:00:00Z