Telomerase activation by the E6 gene product of human papillomavirus type 16.
about
Inactivation of p53 rescues the maintenance of high risk HPV DNA genomes deficient in expression of E6Immortalization of human mammary epithelial cells is associated with inactivation of the p14ARF-p53 pathwayRole of the PDZ domain-binding motif of the oncoprotein E6 in the pathogenesis of human papillomavirus type 31Inactivation of the CYLD deubiquitinase by HPV E6 mediates hypoxia-induced NF-kappaB activationThe global transcriptional effects of the human papillomavirus E6 protein in cervical carcinoma cell lines are mediated by the E6AP ubiquitin ligase.An endogenous inhibitor of human immunodeficiency virus in human lymphocytes is overcome by the viral Vif protein.Human telomerase and its regulationHuman papillomavirus oncoprotein E6 inactivates the transcriptional coactivator human ADA3Human scribble (Vartul) is targeted for ubiquitin-mediated degradation by the high-risk papillomavirus E6 proteins and the E6AP ubiquitin-protein ligaseIdentification of a novel telomerase repressor that interacts with the human papillomavirus type-16 E6/E6-AP complexMicroRNA 203 expression in keratinocytes is dependent on regulation of p53 levels by E6Human papillomavirus 16 E6 oncoprotein binds to interferon regulatory factor-3 and inhibits its transcriptional activityDown-regulation of GATA-3 expression during human papillomavirus-mediated immortalization and cervical carcinogenesisMammary epithelial cell transformation: insights from cell culture and mouse models.Immortalization of Primary Keratinocytes and Its Application to Skin ResearchHuman Papillomavirus (HPV)-associated Oral Cancers and Treatment StrategiesBovine and human papillomaviruses: a comparative reviewMolecular mechanisms of HPV mediated neoplastic progressionFunctional Roles of E6 and E7 Oncoproteins in HPV-Induced Malignancies at Diverse Anatomical SitesMolecular interactions between telomerase and the tumor suppressor protein p53 in vitroSonoporation delivery of monoclonal antibodies against human papillomavirus 16 E6 restores p53 expression in transformed cervical keratinocytesMyc activates telomeraseStructure based identification and characterization of flavonoids that disrupt human papillomavirus-16 E6 functionHuman keratinocytes are efficiently immortalized by a Rho kinase inhibitorPapillomavirus E6 oncoproteins.PKN binds and phosphorylates human papillomavirus E6 oncoprotein.HPV16 E7 protein and hTERT proteins defective for telomere maintenance cooperate to immortalize human keratinocytesThe human papillomavirus 16 E6 protein binds to Fas-associated death domain and protects cells from Fas-triggered apoptosis.Human papillomavirus E6 and Myc proteins associate in vivo and bind to and cooperatively activate the telomerase reverse transcriptase promoterThe bovine papillomavirus E6 oncoprotein interacts with paxillin and disrupts the actin cytoskeleton.HPV E6, E6AP and cervical cancer.Downregulation of SMG-1 in HPV-positive head and neck squamous cell carcinoma due to promoter hypermethylation correlates with improved survival.hTERT promoter activity and CpG methylation in HPV-induced carcinogenesismiR-375 activates p21 and suppresses telomerase activity by coordinately regulating HPV E6/E7, E6AP, CIP2A, and 14-3-3ζNovel isolation and biochemical characterization of immortalized fibroblasts for tissue engineering vocal fold lamina propria.Human telomeres maintain their overhang length at senescence.Human papillomavirus and urological tumours: I. Basic science and role in penile cancer.Role of the E1--E4 protein in the differentiation-dependent life cycle of human papillomavirus type 31.Microarray analysis identifies interferon-inducible genes and Stat-1 as major transcriptional targets of human papillomavirus type 31.Human papillomavirus type 16 E6 induces self-ubiquitination of the E6AP ubiquitin-protein ligase
P2860
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P2860
Telomerase activation by the E6 gene product of human papillomavirus type 16.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh
1996年學術文章
@zh-hant
name
Telomerase activation by the E6 gene product of human papillomavirus type 16.
@en
type
label
Telomerase activation by the E6 gene product of human papillomavirus type 16.
@en
prefLabel
Telomerase activation by the E6 gene product of human papillomavirus type 16.
@en
P2093
P356
P1433
P1476
Telomerase activation by the E6 gene product of human papillomavirus type 16.
@en
P2093
Klingelhutz AJ
McDougall JK
P2888
P356
10.1038/380079A0
P407
P577
1996-03-01T00:00:00Z
P6179
1009511813