Heterologous expression of photoreceptor peripherin/rds and Rom-1 in COS-1 cells: assembly, interactions, and localization of multisubunit complexes.
about
Photoreceptor renewal: a role for peripherin/rdsFolding and subunit assembly of photoreceptor peripherin/rds is mediated by determinants within the extracellular/intradiskal EC2 domain: implications for heterogeneous molecular pathologies.Role of the C terminus of the photoreceptor ABCA4 transporter in protein folding, function, and retinal degenerative diseases.Differential requirements for retinal degeneration slow intermolecular disulfide-linked oligomerization in rods versus conesGlutamic acid-rich proteins of rod photoreceptors are natively unfolded.Role of the second intradiscal loop of peripherin/rds in homo and hetero associations.RDS/peripherin gene mutations are frequent causes of central retinal dystrophies.Peripherin-2 and Rom-1 have opposing effects on rod outer segment targeting of retinitis pigmentosa-linked peripherin-2 mutants.Mutant ELOVL4 that causes autosomal dominant stargardt-3 macular dystrophy is misrouted to rod outer segment disksDisulfide-mediated oligomerization of Peripherin/Rds and Rom-1 in photoreceptor disk membranes. Implications for photoreceptor outer segment morphogenesis and degeneration.Modulating expression of peripherin/rds in transgenic mice: critical levels and the effect of overexpression.Uncoupling of photoreceptor peripherin/rds fusogenic activity from biosynthesis, subunit assembly, and targeting: a potential mechanism for pathogenic effects.Differences in RDS trafficking, assembly and function in cones versus rods: insights from studies of C150S-RDSRD3, the protein associated with Leber congenital amaurosis type 12, is required for guanylate cyclase trafficking in photoreceptor cells.The Y141C knockin mutation in RDS leads to complex phenotypes in the mouse.A single valine residue plays an essential role in peripherin/rds targeting to photoreceptor outer segmentsIn situ visualization of protein interactions in sensory neurons: glutamic acid-rich proteins (GARPs) play differential roles for photoreceptor outer segment scaffoldingRDS in cones does not interact with the beta subunit of the cyclic nucleotide gated channel.The role of subunit assembly in peripherin-2 targeting to rod photoreceptor disk membranes and retinitis pigmentosa.The tetraspanin protein peripherin-2 forms a complex with melanoregulin, a putative membrane fusion regulatorIntrafamilial phenotypic variability in families with RDS mutations: exclusion of ROM1 as a genetic modifier for those with retinitis pigmentosaDefective subunit assembly underlies a digenic form of retinitis pigmentosa linked to mutations in peripherin/rds and rom-1.Varying the GARP2-to-RDS Ratio Leads to Defects in Rim Formation and Rod and Cone Function.Association of a photoreceptor-specific tetraspanin protein, ROM-1, with triton X-100-resistant membrane rafts from rod outer segment disk membranes.Fusion between retinal rod outer segment membranes and model membranes: functional assays and role for peripherin/rds.Deletional analysis of the rod photoreceptor cell peripherin/RDS carboxy-terminal regionTransgenic animal studies of human retinal disease caused by mutations in peripherin/rds.PRPH2/RDS and ROM-1: Historical context, current views and future considerations.Structural characterization of the second intra-discal loop of the photoreceptor tetraspanin RDSEvidence from normal and degenerating photoreceptors that two outer segment integral membrane proteins have separate transport pathways.Transmembrane interactions are needed for KAI1/CD82-mediated suppression of cancer invasion and metastasis.The C terminus of peripherin/rds participates in rod outer segment targeting and alignment of disk incisures.Membrane curvature generation by a C-terminal amphipathic helix in peripherin-2/rds, a tetraspanin required for photoreceptor sensory cilium morphogenesisThe role of the photoreceptor ABC transporter ABCA4 in lipid transport and Stargardt macular degeneration.Outer segment oligomerization of Rds: evidence from mouse models and subcellular fractionation.An unconventional secretory pathway mediates the cilia targeting of peripherin/rdsHeterologous expression of WT and mutant photoreceptor peripherin/rds in Madin Darby canine kidney cells: an assessment of fusogenic function.Molecular basis for photoreceptor outer segment architecture.AAV Vectors for FRET-Based Analysis of Protein-Protein Interactions in Photoreceptor Outer Segments.Evidence for specific tetraspanin homodimers: inhibition of palmitoylation makes cysteine residues available for cross-linking.
P2860
Q28218313-B87DC4FC-DBE8-46DD-A862-5FC319A96C66Q28350970-EF257F88-58FD-438B-9CFE-1952C23FFA45Q30373731-C591333A-EBEA-4772-A8DF-E16A1281C2C3Q30485964-1DA8B753-C0C2-40A3-A1BD-F987A5E5B1ADQ33226936-91C684F8-B6AD-48FE-8DF8-4DA861EAB930Q33662611-D7F1B7C5-13EA-4867-A7CB-C3DC5199F988Q33679218-3668FC41-9B4C-4B84-BFC4-0E28689B0CA0Q33725907-06C43189-8193-40C0-A24D-5938470D2EB5Q33761007-EA5A159D-B435-4245-A6E9-4B9D137D487FQ33890711-AD714D19-A0B6-4CC5-AB24-7844EF5435CEQ34119855-8B5D8B3A-6E8A-4EBB-B28C-55D0FF5C7CEAQ34333788-BEC7A238-899A-4A78-88C0-DC0EC2F06EFBQ34341141-CA3EF77F-9C3F-4490-BB7B-21B1B2BE93A1Q34397146-3645C1DE-8E14-487F-A089-F76C5F0AAEC9Q34463210-4519F40D-D9C9-4740-846B-2E68235A05ABQ34559297-229D7BDC-FE6E-48FC-97A3-1FC1DA8C249BQ35172387-1E962611-2847-4B2E-8827-AC729A60DDC9Q35180510-7F06B5FA-74BC-4660-9B67-F931954D49AAQ35670460-AD99D1B2-BC07-414B-871F-B4883A60EEF6Q35754832-40BF84D9-C8BE-41C3-B61A-F586BB4EFF72Q35762932-CF7C2E40-6F20-4087-8F94-70F347C0BAA3Q35926100-0E78A9B6-3F85-49A8-9680-F2D338934FD3Q36425001-20DF5DE6-774D-4A29-ADB3-202C7EFF3C95Q36519848-4CCF75C7-F7E1-45FD-BF98-11FD99225F3DQ36519858-403E3A93-AE50-485F-8FCE-CC614A250279Q36560375-955F992C-3C5B-4BC4-9DF3-9731E776961AQ36717097-68A01CA1-191F-44C0-80F7-52802FB64E67Q36829127-FE831828-32FF-4979-BFE9-62C412A37244Q36839752-B4FFDC59-0E47-49C0-BDD3-618D0B7D2F3BQ36886050-2C590818-2B77-472D-82C3-F06B186765F5Q37071920-AE66CBBF-9DE7-4D8C-A7D2-BC5A0FE37BA4Q37221245-D8EAC59C-BFA1-468D-8B37-74D4D1FF06E4Q37226399-FD6B36F3-3FA3-4BF2-9309-9A0B7C57413EQ37351985-A02A3EA7-B1BE-4C5F-B98F-9E26ED62C40EQ37457875-85245E6D-5FCD-4BF9-B37C-153FCB58ED1BQ37479554-32F201E0-37DC-4917-ABC1-92B75B3088ADQ38302201-CB6FE769-EFCE-42C0-B9A4-52204675F014Q38853535-03B86A97-D0B0-47C4-AAC9-9C9283D79E48Q40624978-13A15B21-76B4-42DF-BFB5-FA019F9497F8Q40626692-68ECAA71-243F-443C-ADBF-C4C7E828AA49
P2860
Heterologous expression of photoreceptor peripherin/rds and Rom-1 in COS-1 cells: assembly, interactions, and localization of multisubunit complexes.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年学术文章
@wuu
1995年学术文章
@zh-cn
1995年学术文章
@zh-hans
1995年学术文章
@zh-my
1995年学术文章
@zh-sg
1995年學術文章
@yue
1995年學術文章
@zh
1995年學術文章
@zh-hant
name
Heterologous expression of pho ...... ion of multisubunit complexes.
@en
type
label
Heterologous expression of pho ...... ion of multisubunit complexes.
@en
prefLabel
Heterologous expression of pho ...... ion of multisubunit complexes.
@en
P356
P1433
P1476
Heterologous expression of pho ...... tion of multisubunit complexes
@en
P2093
A F Goldberg
R S Molday
P304
14213-14219
P356
10.1021/BI00043A028
P407
P577
1995-10-01T00:00:00Z