Protein kinase B/Akt activity is involved in renal TGF-beta1-driven epithelial-mesenchymal transition in vitro and in vivo.
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Multi-walled carbon nanotubes directly induce epithelial-mesenchymal transition in human bronchial epithelial cells via the TGF-β-mediated Akt/GSK-3β/SNAIL-1 signalling pathwayTGF-beta-induced epithelial to mesenchymal transitionThe tale of transforming growth factor-beta (TGFbeta) signaling: a soigné enigma.Deletion of Irs2 causes reduced kidney size in mice: role for inhibition of GSK3beta?Signaling via Alk5 controls the ontogeny of lung Clara cells.TGF-beta-mediated phosphorylation of hnRNP E1 induces EMT via transcript-selective translational induction of Dab2 and ILEICorrelation between PKB/Akt, GSK-3β expression and tubular epithelial-mesenchymal transition in renal allografts with chronic active antibody-mediated rejection.Anti-fibrogenic effect of PPAR-γ agonists in human intestinal myofibroblasts.PPAR-γ ligands repress TGFβ-induced myofibroblast differentiation by targeting the PI3K/Akt pathway: implications for therapy of fibrosis.HDAC class I inhibitor, Mocetinostat, reverses cardiac fibrosis in heart failure and diminishes CD90+ cardiac myofibroblast activationAkt2 is involved in loss of epithelial cells and renal fibrosis following unilateral ureteral obstruction.PTEN loss induces epithelial--mesenchymal transition in human colon cancer cells.Troglitazone attenuates TGF-β1-induced EMT in alveolar epithelial cells via a PPARγ-independent mechanism.β-Galactoside α2,6-sialyltranferase 1 promotes transforming growth factor-β-mediated epithelial-mesenchymal transition.Matrix rigidity regulates a switch between TGF-β1-induced apoptosis and epithelial-mesenchymal transition.AGEs-Induced IL-6 Synthesis Precedes RAGE Up-Regulation in HEK 293 Cells: An Alternative Inflammatory Mechanism?Molecular biological characteristics of the recruitment of hematopoietic stem cells from bone marrow niche in chronic myeloid leukemia.Both ERK/MAPK and TGF-Beta/Smad signaling pathways play a role in the kidney fibrosis of diabetic mice accelerated by blood glucose fluctuation.Calpain-2 activates Akt via TGF-β1-mTORC2 pathway in pulmonary artery smooth muscle cellsAstragaloside IV ameliorates renal injury in db/db mice.Allelic depletion of grem1 attenuates diabetic kidney disease.Disruption of E-cadherin by matrix metalloproteinase directly mediates epithelial-mesenchymal transition downstream of transforming growth factor-beta1 in renal tubular epithelial cells.MG132 ameliorates kidney lesions by inhibiting the degradation of Smad7 in streptozotocin-induced diabetic nephropathy.Activated protein C: a potential cardioprotective factor against ischemic injury during ischemia/reperfusionTGF-beta-dependent and -independent roles of STRAP in cancer.Regulation and function of miRNA-21 in health and disease.Molecular targets in the discovery and development of novel antimetastatic agents: current progress and future prospects.Potential role of Akt signaling in chronic kidney disease.Epithelial-mesenchymal transition as a fundamental underlying pathogenic process in COPD airways: fibrosis, remodeling and cancer.TGF-β: the connecting link between nephropathy and fibrosis.Saponins from the roots of Platycodon grandiflorum suppresses TGFβ1-induced epithelial-mesenchymal transition via repression of PI3K/Akt, ERK1/2 and Smad2/3 pathway in human lung carcinoma A549 cells.Secreted products of macrophages exposed to calcium oxalate crystals induce epithelial mesenchymal transition of renal tubular cells via RhoA-dependent TGF-β1 pathway.Heat shock protein 90 inhibitor attenuates renal fibrosis through degradation of transforming growth factor-β type II receptor.Next-generation sequencing identifies TGF-β1-associated gene expression profiles in renal epithelial cells reiterated in human diabetic nephropathyInsulin receptor substrate 2 and FoxO3a signalling are involved in E-cadherin expression and transforming growth factor-β1-induced repression in kidney epithelial cells.Strain-induced proliferation requires the phosphatidylinositol 3-kinase/AKT/glycogen synthase kinase pathway.TRIP-1 via AKT modulation drives lung fibroblast/myofibroblast trans-differentiation.Divergent roles of Smad3 and PI3-kinase in murine adriamycin nephropathy indicate distinct mechanisms of proteinuria and fibrogenesis.N-cadherin is overexpressed in Crohn's stricture fibroblasts and promotes intestinal fibroblast migration.The Akt-FoxO3a-manganese superoxide dismutase pathway is involved in the regulation of oxidative stress in diabetic nephropathy.
P2860
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P2860
Protein kinase B/Akt activity is involved in renal TGF-beta1-driven epithelial-mesenchymal transition in vitro and in vivo.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Protein kinase B/Akt activity ...... ansition in vitro and in vivo.
@en
type
label
Protein kinase B/Akt activity ...... ansition in vitro and in vivo.
@en
prefLabel
Protein kinase B/Akt activity ...... ansition in vitro and in vivo.
@en
P2093
P2860
P1476
Protein kinase B/Akt activity ...... ansition in vitro and in vivo.
@en
P2093
Catherine Godson
Derek P Brazil
Jayesh J Kattla
Mediha Heljic
Rosemarie M Carew
P2860
P304
P356
10.1152/AJPRENAL.00548.2007
P577
2008-05-21T00:00:00Z