Dr. Jekyll and Mr. Hyde: The Two Faces of the FUS/EWS/TAF15 Protein Family.
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RNA Binding Proteins in the miRNA PathwayCytoplasmic sequestration of FUS/TLS associated with ALS alters histone marks through loss of nuclear protein arginine methyltransferase 1.EWS and FUS bind a subset of transcribed genes encoding proteins enriched in RNA regulatory functionsRNA Polymerase II C-Terminal Domain: Tethering Transcription to Transcript and TemplateNew strategies in ewing sarcoma: lost in translation?Microarray analysis of peripheral blood lymphocytes from ALS patients and the SAFE detection of the KEGG ALS pathway.Assemblages: functional units formed by cellular phase separationFET proteins TAF15 and EWS are selective markers that distinguish FTLD with FUS pathology from amyotrophic lateral sclerosis with FUS mutations.Functions of FUS/TLS from DNA repair to stress response: implications for ALS.Comprehensive gene expression profiling reveals synergistic functional networks in cerebral vessels after hypertension or hypercholesterolemia.Oncogenic fusion protein EWS-FLI1 is a network hub that regulates alternative splicing.The cell cycle regulator CCDC6 is a key target of RNA-binding protein EWS.A Systematic Analysis of Factors Localized to Damaged Chromatin Reveals PARP-Dependent Recruitment of Transcription FactorsUvrag targeting by Mir125a and Mir351 modulates autophagy associated with Ewsr1 deficiencyNuclear carrier and RNA-binding proteins in frontotemporal lobar degeneration associated with fused in sarcoma (FUS) pathological changes.Expression of Fused in sarcoma mutations in mice recapitulates the neuropathology of FUS proteinopathies and provides insight into disease pathogenesis.A multifunctional protein EWS regulates the expression of Drosha and microRNAs.Toxic PRn poly-dipeptides encoded by the C9orf72 repeat expansion block nuclear import and export.Pediatric sarcomas: translating molecular pathogenesis of disease to novel therapeutic possibilities.Blocking the road, stopping the engine or killing the driver? Advances in targeting EWS/FLI-1 fusion in Ewing sarcoma as novel therapy.TDP-43 and FUS RNA-binding proteins bind distinct sets of cytoplasmic messenger RNAs and differently regulate their post-transcriptional fate in motoneuron-like cells.EWS represses cofilin 1 expression by inducing nuclear retention of cofilin 1 mRNA.Identification of mutations, gene expression changes and fusion transcripts by whole transcriptome RNAseq in docetaxel resistant prostate cancer cellsThe RNA Pol II sub-complex hsRpb4/7 is required for viability of multiple human cell linesFET proteins regulate lifespan and neuronal integrity.FUS regulates genes coding for RNA-binding proteins in neurons by binding to their highly conserved introns.Genetic mutations in RNA-binding proteins and their roles in ALS.RGG boxes within the TET/FET family of RNA-binding proteins are functionally distinct.Differential interaction of PRMT1 with RGG-boxes of the FET family proteins EWS and TAF15.S-adenosyl-methionine (SAM) alters the transcriptome and methylome and specifically blocks growth and invasiveness of liver cancer cells.TAF15b, involved in the autonomous pathway for flowering, represses transcription of FLOWERING LOCUS C.Lysines in the RNA Polymerase II C-Terminal Domain Contribute to TAF15 Fibril Recruitment.Transportin 1 colocalization with Fused in Sarcoma (FUS) inclusions is not characteristic for amyotrophic lateral sclerosis-FUS confirming disrupted nuclear import of mutant FUS and distinguishing it from frontotemporal lobar degeneration with FUS iSATB2 enhances migration and invasion in osteosarcoma by regulating genes involved in cytoskeletal organization.Fused in Sarcoma Neuropathology in Neurodegenerative Disease.A cytoplasmic long noncoding RNA LINC00470 as a new AKT activator to mediate glioblastoma cell autophagy.
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Dr. Jekyll and Mr. Hyde: The Two Faces of the FUS/EWS/TAF15 Protein Family.
description
2010 nî lūn-bûn
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2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年學術文章
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name
Dr. Jekyll and Mr. Hyde: The Two Faces of the FUS/EWS/TAF15 Protein Family.
@en
type
label
Dr. Jekyll and Mr. Hyde: The Two Faces of the FUS/EWS/TAF15 Protein Family.
@en
prefLabel
Dr. Jekyll and Mr. Hyde: The Two Faces of the FUS/EWS/TAF15 Protein Family.
@en
P2860
P356
P1433
P1476
Dr. Jekyll and Mr. Hyde: The Two Faces of the FUS/EWS/TAF15 Protein Family
@en
P2093
Heinrich Kovar
P2860
P304
P356
10.1155/2011/837474
P577
2010-12-09T00:00:00Z