The PML-RAR alpha gene product of the t(15;17) translocation inhibits retinoic acid-induced granulocytic differentiation and mediated transactivation in human myeloid cells.
about
Autophagy in malignant transformation and cancer progressionBCL-2 cooperates with promyelocytic leukemia retinoic acid receptor alpha chimeric protein (PMLRARalpha) to block neutrophil differentiation and initiate acute leukemia.New role for granulocyte colony-stimulating factor-induced extracellular signal-regulated kinase 1/2 in histone modification and retinoic acid receptor α recruitment to gene promoters: relevance to acute promyelocytic leukemia cell differentiation.Active repression by unliganded retinoid receptors in development: less is sometimes moreCooperation of cytokine signaling with chimeric transcription factors in leukemogenesis: PML-retinoic acid receptor alpha blocks growth factor-mediated differentiation.A PMLRARalpha transgene initiates murine acute promyelocytic leukemiaAcute leukemia with promyelocytic features in PML/RARalpha transgenic mice.Transgenic expression of PML/RARalpha impairs myelopoiesis.Physical and functional interactions between cellular retinoic acid binding protein II and the retinoic acid-dependent nuclear complex.A retrovirus carrying the promyelocyte-retinoic acid receptor PML-RARalpha fusion gene transforms haematopoietic progenitors in vitro and induces acute leukaemias.Leukemic transformation by the v-ErbA oncoprotein entails constitutive binding to and repression of an erythroid enhancer in vivo.Antagonistic Interactions between Extracellular Signal-Regulated Kinase Mitogen-Activated Protein Kinase and Retinoic Acid Receptor Signaling in Colorectal Cancer Cells.
P2860
Q27000191-CDCD824B-68E4-4DE7-AB88-2F431D7820C6Q33335885-3AB8A465-8548-4A75-8BC1-5C8DB3EE4CC3Q35102049-2B6AE594-FC62-4C7D-9CD7-BB805C001E0DQ35116527-8AF1200B-AEFF-47FB-88F4-E2DDD0B525E6Q35150597-1EAF6164-06B5-4962-A996-1F5C4B41612DQ36049975-7F3A41E3-A212-4AA6-9F4B-270B05E60205Q36771988-4FF225A1-54E7-4DB9-B515-68188F196E66Q37448452-4EEB7843-E725-4495-B4EF-530231DC49F7Q39448301-3E7BD0F1-4500-4F07-8ACA-45250F925E7FQ41065219-7B0574A1-67BE-4789-AF0B-31191E57D0CBQ42663412-557C912C-C833-46FF-961A-00C119A43DB9Q50284827-5117D3B9-C379-4D44-8284-57F4BE37689C
P2860
The PML-RAR alpha gene product of the t(15;17) translocation inhibits retinoic acid-induced granulocytic differentiation and mediated transactivation in human myeloid cells.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
The PML-RAR alpha gene product ...... vation in human myeloid cells.
@en
type
label
The PML-RAR alpha gene product ...... vation in human myeloid cells.
@en
prefLabel
The PML-RAR alpha gene product ...... vation in human myeloid cells.
@en
P2093
P1433
P1476
The PML-RAR alpha gene product ...... vation in human myeloid cells.
@en
P2093
F Farzaneh
P Rousselot
S Castaigne
P304
P407
P577
1994-02-01T00:00:00Z