The G protein alpha s subunit incorporates [3H]palmitic acid and mutation of cysteine-3 prevents this modification.
about
Myristoylation and differential palmitoylation of the HCK protein-tyrosine kinases govern their attachment to membranes and association with caveolaeFunctional expression of the taste specific G-protein, alpha-gustducinGAIP is membrane-anchored by palmitoylation and interacts with the activated (GTP-bound) form of G alpha i subunitsDifferential distribution of alpha subunits and beta gamma subunits of heterotrimeric G proteins on Golgi membranes of the exocrine pancreasRegulation of G proteins by covalent modificationA proline-rich region and nearby cysteine residues target XLalphas to the Golgi complex regionPosttranslational modification of tubulin by palmitoylation: I. In vivo and cell-free studiesDegradation of the non-palmitoylated invertebrate visual guanine-nucleotide binding protein, iGq alpha(C3,4A), by the ubiquitin-proteasomal pathway is regulated by its activation and translocation to the cytoplasm.Human RAS superfamily proteins and related GTPases.Persistent membrane association of activated and depalmitoylated G protein alpha subunitsReceptor regulation of G-protein palmitoylationStudies of the regulation and function of the Gs alpha gene Gnas using gene targeting technology.Purification and characterization of smooth muscle cell caveolaeCysteine3 of Src family protein tyrosine kinase determines palmitoylation and localization in caveolae.Palmitoylation cycles and regulation of protein function (Review).The role of palmitoylation of the guanine nucleotide binding protein G11 alpha in defining interaction with the plasma membrane.Hydrophobicity and subunit interactions of rod outer segment proteins investigated using Triton X-114 phase partitioning.Regulation of membrane and subunit interactions by N-myristoylation of a G protein alpha subunit in yeast.Functional importance of the amino terminus of Gq alpha.Activated G Protein Gαs Samples Multiple Endomembrane Compartments.Lipid-modified, cysteinyl-containing peptides of diverse structures are efficiently S-acylated at the plasma membrane of mammalian cells.Palmitoylation: a post-translational modification that regulates signalling from G-protein coupled receptors.Effects of lovastatin on adenylyl cyclase activity and G proteins in GH4C1 cells.Palmitoylation but not the extreme amino-terminus of Gq alpha is required for coupling to the NK2 receptor.Palmitoylation of multiple Src-family kinases at a homologous N-terminal motif.N-terminal fatty acylation of the alpha-subunit of the G-protein Gi1: only the myristoylated protein is a substrate for palmitoylation.The alpha-subunits of G-proteins G12 and G13 are palmitoylated, but not amidically myristoylated.Rapid plasma membrane anchoring of newly synthesized p59fyn: selective requirement for NH2-terminal myristoylation and palmitoylation at cysteine-3.The palmitoylation status of the G-protein G(o)1 alpha regulates its activity of interaction with the plasma membrane.Autopalmitoylation of tubulin.Membrane association and conformational change of palmitoylated G(o)alpha.Palmitoylation participates in G protein coupled signal transduction by affecting its oligomerization.Gαs protein binds ubiquitin to regulate epidermal growth factor receptor endosomal sorting.A cysteine-11 to serine mutant of G alpha12 impairs activation through the thrombin receptor.Equivalent regulation of wild type and an epitope-tagged variant of Gs alpha by the IP prostanoid receptor following expression in neuroblastoma x glioma hybrid, NG108-15, cells.
P2860
Q24323219-76BBAC9C-0D25-4F23-A12D-09BE7741066DQ24528201-5C020152-AE93-4081-ABAF-1B8295B34027Q24655992-6027790B-6A32-4F55-90E7-6FE741EBD0C7Q24671849-15BAFA1E-60AD-443A-A8A8-26611602BC29Q28213744-4D705633-81C6-4BB7-9FF1-30FC7507E2CAQ28568448-F04F3C1B-C5BA-4E38-8EBA-948F28308703Q30428021-00C354BB-6DD3-4CB4-95E4-9F57A43CAA24Q33291275-EB40FFD6-3160-4AB6-8808-4B505D3D048EQ33689727-37FCB9BE-3898-4374-82AB-B500E7993E2AQ34810345-C5FA641F-47B7-483B-8C9B-31618815CB33Q35135424-A8039A52-F067-42B1-85D4-52612461BC0DQ36076341-BA174336-1DB2-4E47-A441-F4FB13228378Q36234345-8B2D39E6-1FB2-43F8-85D8-20F44F3BDA84Q36382857-D9B24F32-4E6B-46B3-8ACE-4BC59E518CF5Q37377694-F6ABD73E-23FF-4412-870D-828F484D4C68Q38291497-1E747956-237F-4081-B5ED-FA9CA08738D6Q38293210-859DF590-D0F5-434D-A02B-BFF86BD4AF35Q38353936-BBA88C70-B74D-42AA-8654-F16DEC50D454Q38362899-C1D53AEC-5CFC-4876-98BB-5BF054BD85BCQ41161585-F41EE330-1BB2-42B4-AE3D-F4B83D076839Q41182094-BCECDF54-26DB-4B09-8C14-223FA749F45AQ41263689-4D5FAB7C-6CB1-4D6D-8D66-BDFF0B0ACAD3Q41360515-D3B53D7A-91FB-4758-A76A-DBB47E589818Q41429708-72A53582-65A4-4ED1-B8C3-1C7273988724Q41430121-39C9E7C8-95FB-44A9-88BA-AF27E7CADC55Q41430135-BE2B5AB5-88A3-45B0-9A41-526990ED4E54Q41487859-47DC2281-E878-438D-BA0B-EA65DA230AF5Q41838604-541ABA06-93B2-4CFA-ADA6-1224647779EDQ42747057-A0947340-ADB6-4C32-A7F9-B93553729F07Q42847739-8B7E0924-63FE-4767-B138-BF357466B386Q43628462-B10DEE58-6FA6-4F7E-96DE-D17593775EF0Q46837552-03CAF36D-AE8C-44D8-9A3E-1E330C69C892Q47344775-23ED19F5-FCA9-42FB-952E-707288814AEEQ47851938-7E3C24D2-22FE-4753-943F-F03591047D8EQ55481662-C3A0A14D-53E1-4680-A783-6D9BB0F3F770
P2860
The G protein alpha s subunit incorporates [3H]palmitic acid and mutation of cysteine-3 prevents this modification.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
The G protein alpha s subunit ...... -3 prevents this modification.
@en
type
label
The G protein alpha s subunit ...... -3 prevents this modification.
@en
prefLabel
The G protein alpha s subunit ...... -3 prevents this modification.
@en
P2093
P356
P1433
P1476
The G protein alpha s subunit ...... -3 prevents this modification.
@en
P2093
Degtyarev MY
Spiegel AM
P304
P356
10.1021/BI00083A001
P407
P577
1993-08-01T00:00:00Z