Early lipid intermediates in glycosyl-phosphatidylinositol anchor assembly are synthesized in the ER and located in the cytoplasmic leaflet of the ER membrane bilayer.
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Mammalian PIG-L and its yeast homologue Gpi12p are N-acetylglucosaminylphosphatidylinositol de-N-acetylases essential in glycosylphosphatidylinositol biosynthesis150-kDa oxygen-regulated protein (ORP150) functions as a novel molecular chaperone in MDCK cellsInitial enzyme for glycosylphosphatidylinositol biosynthesis requires PIG-P and is regulated by DPM2DPM2 regulates biosynthesis of dolichol phosphate-mannose in mammalian cells: correct subcellular localization and stabilization of DPM1, and binding of dolichol phosphatePIG-B, a membrane protein of the endoplasmic reticulum with a large lumenal domain, is involved in transferring the third mannose of the GPI anchorPIG-A and PIG-H, which participate in glycosylphosphatidylinositol anchor biosynthesis, form a protein complex in the endoplasmic reticulumA homologue of Saccharomyces cerevisiae Dpm1p is not sufficient for synthesis of dolichol-phosphate-mannose in mammalian cellsThe first step of glycosylphosphatidylinositol biosynthesis is mediated by a complex of PIG-A, PIG-H, PIG-C and GPI1.PIG-M transfers the first mannose to glycosylphosphatidylinositol on the lumenal side of the ER.Yeast ARV1 is required for efficient delivery of an early GPI intermediate to the first mannosyltransferase during GPI assembly and controls lipid flow from the endoplasmic reticulum.Analysis of membrane topology and identification of essential residues for the yeast endoplasmic reticulum inositol acyltransferase Gwt1p.PIG-W is critical for inositol acylation but not for flipping of glycosylphosphatidylinositol-anchor.Yeast Gaa1p is required for attachment of a completed GPI anchor onto proteins.Genes for glycosylphosphatidylinositol toxin biosynthesis in Plasmodium falciparum.Characterization and localization of human type10 17beta-hydroxysteroid dehydrogenaseIIGP, a member of the IFN inducible and microbial defense mediating 47 kDa GTPase family, interacts with the microtubule binding protein hook3Requirement of PIG-F and PIG-O for transferring phosphoethanolamine to the third mannose in glycosylphosphatidylinositolCloning of a putative vesicle transport-related protein, RA410, from cultured rat astrocytes and its expression in ischemic rat brainExpression cloning of PIG-L, a candidate N-acetylglucosaminyl-phosphatidylinositol deacetylaseGlycosylphosphatidylinositol-anchor intermediates associate with triton-insoluble membranes in subcellular compartments that include the endoplasmic reticulum.At the poles across kingdoms: phosphoinositides and polar tip growthIntracellular glycosylphosphatidylinositols accumulate on endosomes: toxicity of alpha-toxin to Leishmania major.Specificity in signal transduction among glycosylphosphatidylinositols of Plasmodium falciparum, Trypanosoma brucei, Trypanosoma cruzi and Leishmania spp.Pig-n, a mammalian homologue of yeast Mcd4p, is involved in transferring phosphoethanolamine to the first mannose of the glycosylphosphatidylinositol.Identification of a species-specific inhibitor of glycosylphosphatidylinositol synthesis.Evidence that free GPI glycolipids are essential for growth of Leishmania mexicana.Recent developments in the cell biology and biochemistry of glycosylphosphatidylinositol lipids (review).Secretory pathway of trypanosomatid parasites.Na(+)-I- symport activity is present in membrane vesicles from thyrotropin-deprived non-I(-)-transporting cultured thyroid cellsFormation of reversible disulfide bonds with the protein matrix of the endoplasmic reticulum correlates with the retention of unassembled Ig light chainsSignal transducing molecules and glycosyl-phosphatidylinositol-linked proteins form a caveolin-rich insoluble complex in MDCK cells.A glycosylphosphatidylinositol (GPI)-negative phenotype produced in Leishmania major by GPI phospholipase C from Trypanosoma brucei: topography of two GPI pathways.Characterization of caveolin-rich membrane domains isolated from an endothelial-rich source: implications for human diseaseThe GPI anchor of cell-surface proteins is synthesized on the cytoplasmic face of the endoplasmic reticulum.Identification of six complementation classes involved in the biosynthesis of glycosylphosphatidylinositol anchors in Saccharomyces cerevisiae.Architecture and biosynthesis of the Saccharomyces cerevisiae cell wall.Recent developments in the molecular, biochemical and functional characterization of GPI8 and the GPI-anchoring mechanism [review].Thematic review series: lipid posttranslational modifications. GPI anchoring of protein in yeast and mammalian cells, or: how we learned to stop worrying and love glycophospholipids.The inducibly expressed GTPase localizes to the endoplasmic reticulum, independently of GTP binding.The role of inositol acylation and inositol deacylation in GPI biosynthesis in Trypanosoma brucei.
P2860
Q22009074-326C96CC-F995-479E-90B9-DC17945D414AQ22254183-7FDDBA28-4C88-4B96-AFC8-961B7F6AFFE4Q24289565-754D2FED-765F-45E8-941C-B3D5B0DF5766Q24309978-1A6B1610-E878-440F-A591-0B3F2B9E121BQ24313403-48EDF95D-9C64-4690-9CE9-EDA9754A110CQ24317767-9BE68750-73A0-437F-8E22-7D1738AF51B8Q24322667-F3C72F72-F800-47F3-8B8B-3BC4D0640F92Q24533042-93221810-62E7-4948-8971-9E1AFAD1D891Q24540354-A28E5090-8901-4B82-A74A-C11B78C1DA0FQ27933944-71D4F0AA-ACE9-4635-A538-AF61FD9A82BDQ27937181-EBEF174B-BA04-40B4-90CA-C503AB5B242AQ27937797-59B2B3D0-E23D-46B9-9796-BC251BAEE094Q27940362-31E1DB8A-7049-4576-9669-ECE522C31173Q27972986-0F941AEE-222A-4923-BE3C-A00531311161Q28216369-BB06571E-7FA4-4BFD-8C29-32501A04C167Q28255726-5536B3BE-6A40-4F3F-ACF7-AC38E58A17D1Q28511718-6E6A4B4A-64A0-4906-8711-1D841FF69145Q28568014-8744420E-A28A-4D88-93E2-B8F157F9E98AQ28570907-F35B88A6-1AD4-46F7-BCE2-18CA7B013925Q33179043-72BAF7C9-2EE1-4D6F-88A7-CEE2EE725AF3Q33737494-27D7EEF7-EA5D-4390-A693-F1D79A08C4E6Q33770551-6A1521B7-4A20-49A3-8238-CFCE23774012Q33785926-C2CD5D6D-0357-4755-AC10-19B7387706B9Q33881662-0570F327-1380-437A-8C55-9D60E324D4C7Q33887644-4543341E-C709-4029-B434-37FCB5E38940Q33890917-04A7C55D-ACD9-4924-A0A4-CBE2D3C34379Q33902904-75CC0181-64D9-4C58-98B2-64E1D4C3C50AQ33969495-8DA074C3-F08C-4435-90A3-279CB9D19D8EQ35197721-D22DE5E9-D0D0-4CC9-AF66-191DDBDC9443Q35848909-25A27DD6-097A-4609-93A9-8B4F3B040397Q36232566-7FD2A5F7-2328-4F75-81AE-C70061A29396Q36233819-BBB92F3D-9472-49AC-AF88-456359C55F44Q36234407-879A9D35-1F19-4AE3-BDA2-BF9DD30B196CQ36234721-261EA788-C8DE-464E-B06F-BE344C6C0CD8Q36235994-657E1451-B388-49DD-BE21-0B540982C0D1Q36466304-CE754DBA-9100-4177-9900-BB6ABE5A26B9Q36511643-11291F8D-D9B0-418A-B9E0-953586309247Q36759924-F3907B33-A214-4A9B-BBDB-AD9CBA6A0350Q36853414-EDB781F3-1220-4B5D-B852-E837F89F21D7Q37619642-E6D246EB-C86A-4A6A-95FB-7170AD35765C
P2860
Early lipid intermediates in glycosyl-phosphatidylinositol anchor assembly are synthesized in the ER and located in the cytoplasmic leaflet of the ER membrane bilayer.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年学术文章
@wuu
1993年学术文章
@zh-cn
1993年学术文章
@zh-hans
1993年学术文章
@zh-my
1993年学术文章
@zh-sg
1993年學術文章
@yue
1993年學術文章
@zh
1993年學術文章
@zh-hant
name
Early lipid intermediates in g ...... et of the ER membrane bilayer.
@en
type
label
Early lipid intermediates in g ...... et of the ER membrane bilayer.
@en
prefLabel
Early lipid intermediates in g ...... et of the ER membrane bilayer.
@en
P2860
P356
P1476
Early lipid intermediates in g ...... let of the ER membrane bilayer
@en
P2093
J Vidugiriene
P2860
P304
P356
10.1083/JCB.121.5.987
P407
P577
1993-06-01T00:00:00Z