about
The Rbx1 subunit of SCF and VHL E3 ubiquitin ligase activates Rub1 modification of cullins Cdc53 and Cul2pVHL acts as an adaptor to promote the inhibitory phosphorylation of the NF-kappaB agonist Card9 by CK2High-throughput screening to identify inhibitors of lysine demethylasesMuf1, a novel Elongin BC-interacting leucine-rich repeat protein that can assemble with Cul5 and Rbx1 to reconstitute a ubiquitin ligaseIdentification of Elongin C and Skp1 sequences that determine Cullin selectionHistone demethylase jumonji AT-rich interactive domain 1B (JARID1B) controls mammary gland development by regulating key developmental and lineage specification genesDegradation of p53 by adenovirus E4orf6 and E1B55K proteins occurs via a novel mechanism involving a Cullin-containing complexThe KDM5 family is required for activation of pro-proliferative cell cycle genes during adipocyte differentiationHistone demethylase RBP2 is critical for breast cancer progression and metastasis.Epigenetic Regulation by Lysine Demethylase 5 (KDM5) Enzymes in Cancer.Significance of glioma-associated oncogene homolog 1 (GLI1) expression in claudin-low breast cancer and crosstalk with the nuclear factor kappa-light-chain-enhancer of activated B cells (NFκB) pathway.Loss of the retinoblastoma binding protein 2 (RBP2) histone demethylase suppresses tumorigenesis in mice lacking Rb1 or Men1Illumina Sequencing of Bisulfite-Converted DNA Libraries.High-Throughput Deep Sequencing for Mapping Mammalian DNA Methylation.Epigenetic mechanisms in commonly occurring cancers.Coordinated repression of cell cycle genes by KDM5A and E2F4 during differentiation.Identification of small molecule inhibitors of Jumonji AT-rich interactive domain 1B (JARID1B) histone demethylase by a sensitive high throughput screen.Structural Basis for KDM5A Histone Lysine Demethylase Inhibition by Diverse CompoundsAn easy and efficient inducible CRISPR/Cas9 platform with improved specificity for multiple gene targetingBoth BC-box motifs of adenovirus protein E4orf6 are required to efficiently assemble an E3 ligase complex that degrades p53.KDM5 lysine demethylases are involved in maintenance of 3'UTR length.Histone demethylases set the stage for cancer metastasis.The retinoblastoma binding protein RBP2 is an H3K4 demethylase.Histone demethylase RBP2 promotes lung tumorigenesis and cancer metastasis.The von Hippel-Lindau tumor suppressor protein regulates gene expression and tumor growth through histone demethylase JARID1C.Hypoxia-inducible factor linked to differential kidney cancer risk seen with type 2A and type 2B VHL mutations.Cell Division Cycle 42 plays a Cell type-Specific role in Lung Tumorigenesis.Insights into the Action of Inhibitor Enantiomers against Histone Lysine Demethylase 5A.Dual roles for transcription factor IIF in promoter escape by RNA polymerase II.The multiplexed CRISPR targeting platformsMultiple tumor suppressors regulate a HIF-dependent negative feedback loop via ISGF3 in human clear cell renal cancerKDM5 histone demethylases repress immune response via suppression of STINGTranscription Factors TFIIF, ELL, and Elongin Negatively Regulate SII-induced Nascent Transcript Cleavage by Non-arrested RNA Polymerase II Elongation IntermediatesA Role for the TFIIH XPB DNA Helicase in Promoter Escape by RNA Polymerase IISpecific chromatin landscapes and transcription factors couple breast cancer subtype with metastatic relapse to lung or brainAnnotation and cluster analysis of long noncoding RNA linked to male sex and estrogen in cancersIdentification and Validation of a Novel Biologics Target in Triple Negative Breast CancerAcquired Resistance to HER2-Targeted Therapies Creates Vulnerability to ATP Synthase InhibitionLong noncoding RNA LINC00336 inhibits ferroptosis in lung cancer by functioning as a competing endogenous RNAPotent BRD4 inhibitor suppresses cancer cell-macrophage interaction
P50
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P50
description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Qin Yan
@ast
Qin Yan
@en
Qin Yan
@es
Qin Yan
@nl
Qin Yan
@sl
type
label
Qin Yan
@ast
Qin Yan
@en
Qin Yan
@es
Qin Yan
@nl
Qin Yan
@sl
prefLabel
Qin Yan
@ast
Qin Yan
@en
Qin Yan
@es
Qin Yan
@nl
Qin Yan
@sl
P1053
E-8893-2012
P106
P1153
36125655600
P31
P3829
P496
0000-0003-4077-453X