Protein kinase C-θ promotes Th17 differentiation via upregulation of Stat3.
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The Novel PKCθ from Benchtop to ClinicProtein kinase C θ regulates the phenotype of murine CD4+ Th17 cellsDiacylglycerol Kinases in T Cell Tolerance and Effector FunctionProtein kinase C in the immune system: from signalling to chromatin regulationIdentification of Tetraazacyclic Compounds as Novel Potent Inhibitors Antagonizing RORγt Activity and Suppressing Th17 Cell DifferentiationInhibition of lysophosphatidic acid receptor ameliorates Sjögren's syndrome in NOD mice.Pharmacological Inhibition of PKCθ Counteracts Muscle Disease in a Mouse Model of Duchenne Muscular Dystrophy.Protein kinase C theta is required for efficient induction of IL-10-secreting T cells.Protein kinase C theta is dispensable for suppression mediated by CD25+CD4+ regulatory T cells.Regulation of Lipid Signaling by Diacylglycerol Kinases during T Cell Development and FunctionThe yin and yang of protein kinase C-theta (PKCθ): a novel drug target for selective immunosuppression.NF-κB Activation in T Helper 17 Cell Differentiation.STAT3 governs hyporesponsiveness and granzyme B-dependent suppressive capacity in human CD4+ T cells.p(⁷⁰S⁶K¹) in the TORC1 pathway is essential for the differentiation of Th17 Cells, but not Th1, Th2, or Treg cells in mice.Intervention of PKC-θ as an immunosuppressive regimen.Involvement of distinct PKC gene products in T cell functionsPKC-theta-mediated signal delivery from the TCR/CD28 surface receptors.Regulation of Th17 Differentiation by IKKα-Dependent and -Independent Phosphorylation of RORγt.Intracellular Delivery of Anti-pPKCθ (Thr538) via Protein Transduction Domain Mimics for Immunomodulation.Cyclic AMP-Responsive Element-Binding Protein (CREB) is Critical in Autoimmunity by Promoting Th17 but Inhibiting Treg Cell Differentiation.SRC1 promotes Th17 differentiation by overriding Foxp3 suppression to stimulate RORγt activity in a PKC-θ-dependent manner.Protein kinase Cθ: the pleiotropic T-cell signalling intermediate.
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Protein kinase C-θ promotes Th17 differentiation via upregulation of Stat3.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
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2012年论文
@zh-cn
name
Protein kinase C-θ promotes Th17 differentiation via upregulation of Stat3.
@en
type
label
Protein kinase C-θ promotes Th17 differentiation via upregulation of Stat3.
@en
prefLabel
Protein kinase C-θ promotes Th17 differentiation via upregulation of Stat3.
@en
P2093
P2860
P356
P1476
Protein kinase C-θ promotes Th17 differentiation via upregulation of Stat3.
@en
P2093
Myung-Ja Kwon
Ruiqing Wang
Zuoming Sun
P2860
P304
P356
10.4049/JIMMUNOL.1102941
P407
P577
2012-05-14T00:00:00Z