Maintaining genetic stability through TP53 mediated checkpoint control.
about
Expression of full-length p53 and its isoform Deltap53 in breast carcinomas in relation to mutation status and clinical parametersLeflunomide: mode of action in the treatment of rheumatoid arthritisSaccharomyces cerevisiae transcription elongation mutants are defective in PUR5 induction in response to nucleotide depletion.Integrity of the N-terminal transcription domain of p53 is required for mutant p53 interference with drug-induced apoptosisThe antioxidant function of the p53 tumor suppressorCell state plasticity, stem cells, EMT, and the generation of intra-tumoral heterogeneity.Chk1 and Cds1: linchpins of the DNA damage and replication checkpoint pathways.A leucine-rich nuclear export signal in the p53 tetramerization domain: regulation of subcellular localization and p53 activity by NES masking.Inactivation of p53 by human T-cell lymphotropic virus type 1 Tax requires activation of the NF-kappaB pathway and is dependent on p53 phosphorylation.A plausible model for the digital response of p53 to DNA damage.Overexpression of c-Myc alters G(1)/S arrest following ionizing radiationDrosophila p53 preserves genomic stability by regulating cell death.ATM and ATR: sensing DNA damage.Phase I dose-escalation study of AZD7762, a checkpoint kinase inhibitor, in combination with gemcitabine in US patients with advanced solid tumorsComplex cisplatin-double strand break (DSB) lesions directly impair cellular non-homologous end-joining (NHEJ) independent of downstream damage response (DDR) pathwaysGenomic alterations associated with loss of heterozygosity for TP53 in Li-Fraumeni syndrome fibroblasts.A p53-dependent S-phase checkpoint helps to protect cells from DNA damage in response to starvation for pyrimidine nucleotides.Diminished origin-licensing capacity specifically sensitizes tumor cells to replication stress.Crosstalk between Aurora-A and p53: frequent deletion or downregulation of Aurora-A in tumors from p53 null mice.Understanding the limitations of radiation-induced cell cycle checkpoints.Gender-related prognostic value and genomic pattern of intra-tumor heterogeneity in colorectal cancer.p53 further extends its reach.A new era of allele-specific diagnostics?Antimicrobial and antiproliferative prospective of kosinostatin - a secondary metabolite isolated from Streptomyces sp.Analysis of the c-myc, K-ras and p53 genes in methylcholanthrene-induced mouse sarcomas.Expression Profiling of Hspb1 and Tp53 Genes through RT-qPCR in Different Cancer Types of Canis familiaris.
P2860
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P2860
Maintaining genetic stability through TP53 mediated checkpoint control.
description
1997 nî lūn-bûn
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1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh
1997年學術文章
@zh-hant
name
Maintaining genetic stability through TP53 mediated checkpoint control.
@en
type
label
Maintaining genetic stability through TP53 mediated checkpoint control.
@en
prefLabel
Maintaining genetic stability through TP53 mediated checkpoint control.
@en
P2093
P1433
P1476
Maintaining genetic stability through TP53 mediated checkpoint control
@en
P2093
P304
P577
1997-01-01T00:00:00Z