A leucine-rich nuclear export signal in the p53 tetramerization domain: regulation of subcellular localization and p53 activity by NES masking.
about
Nuclear import/export of hRPF1/Nedd4 regulates the ubiquitin-dependent degradation of its nuclear substratesThe corepressor mSin3a interacts with the proline-rich domain of p53 and protects p53 from proteasome-mediated degradationSequence analysis of LRPPRC and its SEC1 domain interaction partners suggests roles in cytoskeletal organization, vesicular trafficking, nucleocytosolic shuttling, and chromosome activityMonoubiquitylation promotes mitochondrial p53 translocationCharge modification at multiple C-terminal lysine residues regulates p53 oligomerization and its nucleus-cytoplasm traffickingUSP10 regulates p53 localization and stability by deubiquitinating p53The conserved CPH domains of Cul7 and PARC are protein-protein interaction modules that bind the tetramerization domain of p53Positive regulation of p53 stability and activity by the deubiquitinating enzyme Otubain 1Characterisation of the interface between nucleophosmin (NPM) and p53: potential role in p53 stabilisationHuman NCU-G1 can function as a transcription factor and as a nuclear receptor co-activatorRegulation of human p53 activity and cell localization by alternative splicingRegulation of p53 tetramerization and nuclear export by ARCEndoplasmic reticulum stress induces p53 cytoplasmic localization and prevents p53-dependent apoptosis by a pathway involving glycogen synthase kinase-3betaMammalian WDR12 is a novel member of the Pes1-Bop1 complex and is required for ribosome biogenesis and cell proliferationRepression of SHP-1 expression by p53 leads to trkA tyrosine phosphorylation and suppression of breast cancer cell proliferationp53 mediates the negative regulation of MDM2 by orphan receptor TR3The interferon stimulated gene 54 promotes apoptosisTyrosine phosphorylation of Mdm2 by c-Abl: implications for p53 regulationA masked NES in INI1/hSNF5 mediates hCRM1-dependent nuclear export: implications for tumorigenesisThe NS2 proteins of parvovirus minute virus of mice are required for efficient nuclear egress of progeny virions in mouse cells.Loading and unloading: orchestrating centrosome duplication and spindle assembly by Ran/Crm1CRM1/Ran-mediated nuclear export of p27(Kip1) involves a nuclear export signal and links p27 export and proteolysisGlucocorticoid receptor homodimers and glucocorticoid-mineralocorticoid receptor heterodimers form in the cytoplasm through alternative dimerization interfacesERF nuclear shuttling, a continuous monitor of Erk activity that links it to cell cycle progressionCofactor requirements for nuclear export of Rev response element (RRE)- and constitutive transport element (CTE)-containing retroviral RNAs. An unexpected role for actin.Cancer-associated mutations in the MDM2 zinc finger domain disrupt ribosomal protein interaction and attenuate MDM2-induced p53 degradationPhosphorylation regulates the subcellular location and activity of the snail transcriptional repressorInvolvement of 14-3-3 proteins in nuclear localization of telomeraseStructural Basis of Targeting the Exportin CRM1 in CancerClinical utility of anti-p53 auto-antibody: systematic review and focus on colorectal cancerHydrogen peroxide sensing, signaling and regulation of transcription factorsNuclear export of proteins and drug resistance in cancerControl of Protein Activity and Cell Fate Specification via Light-Mediated Nuclear TranslocationOptogenetic control of nuclear protein export.The coiled coil region (amino acids 129-250) of the tumor suppressor protein adenomatous polyposis coli (APC). Its structure and its interaction with chromosome maintenance region 1 (Crm-1)Structure of mitogen-activated protein kinase-activated protein (MAPKAP) kinase 2 suggests a bifunctional switch that couples kinase activation with nuclear exportRegulation of PI4,5P2 synthesis by nuclear-cytoplasmic shuttling of the Mss4 lipid kinaseNuclear export receptor Xpo1/Crm1 is physically and functionally linked to the spindle pole body in budding yeastp53 Proteoforms and Intrinsic Disorder: An Illustration of the Protein Structure-Function Continuum ConceptArginine methylation regulates the p53 response
P2860
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P2860
A leucine-rich nuclear export signal in the p53 tetramerization domain: regulation of subcellular localization and p53 activity by NES masking.
description
1999 nî lūn-bûn
@nan
1999 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի մարտին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
A leucine-rich nuclear export ...... d p53 activity by NES masking.
@ast
A leucine-rich nuclear export ...... d p53 activity by NES masking.
@en
type
label
A leucine-rich nuclear export ...... d p53 activity by NES masking.
@ast
A leucine-rich nuclear export ...... d p53 activity by NES masking.
@en
prefLabel
A leucine-rich nuclear export ...... d p53 activity by NES masking.
@ast
A leucine-rich nuclear export ...... d p53 activity by NES masking.
@en
P2093
P2860
P356
P1433
P1476
A leucine-rich nuclear export ...... d p53 activity by NES masking.
@en
P2093
G S Jimenez
J M Stommel
N D Marchenko
P2860
P304
P356
10.1093/EMBOJ/18.6.1660
P407
P577
1999-03-01T00:00:00Z