about
Acetaminophen-induced Liver Injury: from Animal Models to HumansPathophysiological significance of c-jun N-terminal kinase in acetaminophen hepatotoxicityA cellular model to study drug-induced liver injury in nonalcoholic fatty liver disease: Application to acetaminophenA direct comparison of methods used to measure oxidized glutathione in biological samples: 2-vinylpyridine and N-ethylmaleimidePlatelets and protease-activated receptor-4 contribute to acetaminophen-induced liver injury in mice.Involvement of connexin43 in acetaminophen-induced liver injury.Molecular forms of HMGB1 and keratin-18 as mechanistic biomarkers for mode of cell death and prognosis during clinical acetaminophen hepatotoxicityCirculating microRNA profiles in human patients with acetaminophen hepatotoxicity or ischemic hepatitis.Mechanisms of acetaminophen-induced cell death in primary human hepatocytes.Serum mitochondrial biomarkers and damage-associated molecular patterns are higher in acetaminophen overdose patients with poor outcome.Glycodeoxycholic acid levels as prognostic biomarker in acetaminophen-induced acute liver failure patientsArgininosuccinate synthetase as a plasma biomarker of liver injury after acetaminophen overdose in rodents and humansLower susceptibility of female mice to acetaminophen hepatotoxicity: Role of mitochondrial glutathione, oxidant stress and c-jun N-terminal kinase.The role of the c-Jun N-terminal kinases 1/2 and receptor-interacting protein kinase 3 in furosemide-induced liver injuryResveratrol prevents protein nitration and release of endonucleases from mitochondria during acetaminophen hepatotoxicity.MicroRNAs as Signaling Mediators and Biomarkers of Drug- and Chemical-Induced Liver Injury.Time course of acetaminophen-protein adducts and acetaminophen metabolites in circulation of overdose patients and in HepaRG cells.Inhibition of pannexin1 channels alleviates acetaminophen-induced hepatotoxicityMitochondrial protein adducts formation and mitochondrial dysfunction during N-acetyl-m-aminophenol (AMAP)-induced hepatotoxicity in primary human hepatocytesAcetaminophen-induced liver injury in rats and mice: comparison of protein adducts, mitochondrial dysfunction, and oxidative stress in the mechanism of toxicity.Benzyl alcohol protects against acetaminophen hepatotoxicity by inhibiting cytochrome P450 enzymes but causes mitochondrial dysfunction and cell death at higher dosesLysosomal instability and cathepsin B release during acetaminophen hepatotoxicity.Lack of Direct Cytotoxicity of Extracellular ATP against Hepatocytes: Role in the Mechanism of Acetaminophen HepatotoxicityCritical review of resveratrol in xenobiotic-induced hepatotoxicity.Bile Acid-Induced Toxicity in HepaRG Cells Recapitulates the Response in Primary Human HepatocytesPurinergic receptor antagonist A438079 protects against acetaminophen-induced liver injury by inhibiting p450 isoenzymes, not by inflammasome activationModels of drug-induced liver injury for evaluation of phytotherapeutics and other natural products.Plasma and liver acetaminophen-protein adduct levels in mice after acetaminophen treatment: dose-response, mechanisms, and clinical implications.Hearing, reactive metabolite formation, and oxidative stress in cochleae after a single acute overdose of acetaminophen: an in vivo studyConnexin32: a mediator of acetaminophen-induced liver injury?Receptor interacting protein kinase 3 is a critical early mediator of acetaminophen-induced hepatocyte necrosis in mice.Low Dose Acetaminophen Induces Reversible Mitochondrial Dysfunction Associated with Transient c-Jun N-Terminal Kinase Activation in Mouse Liver.The gap junction inhibitor 2-aminoethoxy-diphenyl-borate protects against acetaminophen hepatotoxicity by inhibiting cytochrome P450 enzymes and c-jun N-terminal kinase activationProtection against acetaminophen-induced liver injury by allopurinol is dependent on aldehyde oxidase-mediated liver preconditioningNeutrophil activation during acetaminophen hepatotoxicity and repair in mice and humans.Circulating acylcarnitines as biomarkers of mitochondrial dysfunction after acetaminophen overdose in mice and humansMechanistic biomarkers in acetaminophen-induced hepatotoxicity and acute liver failure: from preclinical models to patients.The past and present of serum aminotransferases and the future of liver injury biomarkers.Removal of acetaminophen protein adducts by autophagy protects against acetaminophen-induced liver injury in mice.Caspase Inhibition Prevents Tumor Necrosis Factor-α-Induced Apoptosis and Promotes Necrotic Cell Death in Mouse Hepatocytes in Vivo and in Vitro.
P50
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P50
description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Mitchell R McGill
@ast
Mitchell R McGill
@en
Mitchell R McGill
@es
Mitchell R McGill
@nl
Mitchell R McGill
@sl
type
label
Mitchell R McGill
@ast
Mitchell R McGill
@en
Mitchell R McGill
@es
Mitchell R McGill
@nl
Mitchell R McGill
@sl
prefLabel
Mitchell R McGill
@ast
Mitchell R McGill
@en
Mitchell R McGill
@es
Mitchell R McGill
@nl
Mitchell R McGill
@sl
P106
P21
P31
P496
0000-0002-0401-0463
P569
2000-01-01T00:00:00Z