Suppression of c-myc and c-myb is tightly linked to terminal differentiation induced by IL6 or LIF and not growth inhibition in myeloid leukemia cells.
about
The Gfi-1B proto-oncoprotein represses p21WAF1 and inhibits myeloid cell differentiation.PRDI-BF1/Blimp-1 repression is mediated by corepressors of the Groucho family of proteinsRequirement of c-Myb for p210(BCR/ABL)-dependent transformation of hematopoietic progenitors and leukemogenesisOnly the DNA binding and transactivation domains of c-Myb are required to block terminal differentiation of murine erythroleukemia cellsc-Myc is a critical target for c/EBPalpha in granulopoiesis.Global gene expression in granulosa cells of growing, plateau and atretic dominant follicles in cattleHigh levels of the BCR/ABL oncoprotein are required for the MAPK-hnRNP-E2 dependent suppression of C/EBPalpha-driven myeloid differentiationOpposing actions of c-ets/PU.1 and c-myb protooncogene products in regulating the macrophage-specific promoters of the human and mouse colony-stimulating factor-1 receptor (c-fms) genes.The novel primary response gene MyD118 and the proto-oncogenes myb, myc, and bcl-2 modulate transforming growth factor beta 1-induced apoptosis of myeloid leukemia cells.p53-mediated cell death: relationship to cell cycle control.A novel function for Myc: inhibition of C/EBP-dependent gene activation.A central role for Stat3 in IL-6-induced regulation of growth and differentiation in M1 leukemia cellsTranscriptional repression by blimp-1 (PRDI-BF1) involves recruitment of histone deacetylase.Repression of c-myc is necessary but not sufficient for terminal differentiation of B lymphocytes in vitro.Deregulated c-myb disrupts interleukin-6- or leukemia inhibitory factor-induced myeloid differentiation prior to c-myc: role in leukemogenesis.Differentiation and growth arrest signals are generated through the cytoplasmic region of gp130 that is essential for Stat3 activationBatf promotes growth arrest and terminal differentiation of mouse myeloid leukemia cells.Proto-oncogenes of the fos/jun family of transcription factors are positive regulators of myeloid differentiation.
P2860
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P2860
Suppression of c-myc and c-myb is tightly linked to terminal differentiation induced by IL6 or LIF and not growth inhibition in myeloid leukemia cells.
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
1991年论文
@zh
1991年论文
@zh-cn
name
Suppression of c-myc and c-myb ...... ion in myeloid leukemia cells.
@en
type
label
Suppression of c-myc and c-myb ...... ion in myeloid leukemia cells.
@en
prefLabel
Suppression of c-myc and c-myb ...... ion in myeloid leukemia cells.
@en
P1433
P1476
Suppression of c-myc and c-myb ...... tion in myeloid leukemia cells
@en
P2093
Hoffman-Liebermann B
Liebermann DA
P304
P407
P577
1991-06-01T00:00:00Z