Proto-oncogenes of the fos/jun family of transcription factors are positive regulators of myeloid differentiation.
about
Targeted disruption of the c-fos gene demonstrates c-fos-dependent and -independent pathways for gene expression stimulated by growth factors or oncogenesControl of cell cycle progression by c-Jun is p53 dependentLOT1 is a growth suppressor gene down-regulated by the epidermal growth factor receptor ligands and encodes a nuclear zinc-finger proteinVirally mediated MafB transduction induces the monocyte commitment of human CD34+ hematopoietic stem/progenitor cellsRegulation of HIV-1 transcription in cells of the monocyte-macrophage lineage.Fra-1 induces morphological transformation and increases in vitro invasiveness and motility of epithelioid adenocarcinoma cells.Visna virus-induced activation of MAPK is required for virus replication and correlates with virus-induced neuropathologyGene expression of TPA induced differentiation in HL-60 cells by DNA microarray analysis.Modeling Philadelphia chromosome positive leukemias.Downregulation of c-Jun expression by transcription factor C/EBPalpha is critical for granulocytic lineage commitmentcFos mediates cAMP-dependent generation of ROS and rescue of maturation program in retinoid-resistant acute promyelocytic leukemia cell line NB4-LR1.Transcriptional regulation of myelopoiesis.Expression of immediate early genes, GATA-4, and Nkx-2.5 in adrenergic-induced cardiac hypertrophy and during regression in adult mice.C/EBPalpha directs monocytic commitment of primary myeloid progenitors.Role of Erk1/2 signaling in the regulation of neutrophil versus monocyte development in response to G-CSF and M-CSF.The zinc finger transcription factor Egr-1 potentiates macrophage differentiation of hematopoietic cellsConstitutive c-ets2 expression in M1D+ myeloblast leukemic cells induces their differentiation to macrophagesFos and Jun repress transcription activation by NF-IL6 through association at the basic zipper region.C/EBPalpha induces PU.1 and interacts with AP-1 and NF-kappaB to regulate myeloid developmentLipopolysaccharide-dependent interaction between PU.1 and c-Jun determines production of lipocalin-type prostaglandin D synthase and prostaglandin D2 in macrophages.Increased c-Jun expression and reduced GATA2 expression promote aberrant monocytic differentiation induced by activating PTPN11 mutantsDownregulation of JUNB mRNA expression in advanced phase chronic myelogenous leukemia.Differential gene expression analysis in k562 human leukemia cell line treated with benzene.PU.1 and partners: regulation of haematopoietic stem cell fate in normal and malignant haematopoiesis.Monocyte and macrophage dynamics during atherogenesis.Regulation of monocyte differentiation by specific signaling modules and associated transcription factor networks.Requirement of AP-1 for ceramide-induced apoptosis in human leukemia HL-60 cells.C/EBP alpha:AP-1 leucine zipper heterodimers bind novel DNA elements, activate the PU.1 promoter and direct monocyte lineage commitment more potently than C/EBP alpha homodimers or AP-1p120 nucleolar-proliferating antigen is a direct target of G-CSF signaling during myeloid differentiation.c-Jun is a JNK-independent coactivator of the PU.1 transcription factor.An AP-1 site in the promoter of the human IL-5R alpha gene is necessary for promoter activity in eosinophilic HL60 cells.The orphan nuclear receptor SHP is involved in monocytic differentiation, and its expression is increased by c-Jun.Acute myeloid leukemia fusion proteins deregulate genes involved in stem cell maintenance and DNA repairc-Jun blocks cell differentiation but not growth inhibition or apoptosis of chronic myelogenous leukemia cells induced by STI571 and by histone deacetylase inhibitors.5' upstream sequences of MyD88, an IL-6 primary response gene in M1 cells: detection of functional IRF-1 and Stat factors binding sites.Egr-1 abrogates the block imparted by c-Myc on terminal M1 myeloid differentiation.c-fos and bone loss: a proto-oncogene regulates osteoclast lineage determination.Antisense therapeutics in haematological malignancies.Identification of a minimal cis-element and cognate trans-factor(s) required for induction of Rac2 gene expression during K562 cell differentiation.Commonly dysregulated genes in murine APL cells.
P2860
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P2860
Proto-oncogenes of the fos/jun family of transcription factors are positive regulators of myeloid differentiation.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
Proto-oncogenes of the fos/jun ...... rs of myeloid differentiation.
@en
Proto-oncogenes of the fos/jun ...... rs of myeloid differentiation.
@nl
type
label
Proto-oncogenes of the fos/jun ...... rs of myeloid differentiation.
@en
Proto-oncogenes of the fos/jun ...... rs of myeloid differentiation.
@nl
prefLabel
Proto-oncogenes of the fos/jun ...... rs of myeloid differentiation.
@en
Proto-oncogenes of the fos/jun ...... rs of myeloid differentiation.
@nl
P2093
P2860
P356
P1476
Proto-oncogenes of the fos/jun ...... rs of myeloid differentiation.
@en
P2093
A Abdollahi
B Hoffman-Liebermann
D A Liebermann
P2860
P304
P356
10.1128/MCB.13.2.841
P407
P577
1993-02-01T00:00:00Z