c-Myc is a critical target for c/EBPalpha in granulopoiesis.
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C/EBPα Dysregulation in AML and ALLUp- or downregulation of tescalcin in HL-60 cells is associated with their differentiation to either granulocytic or macrophage-like lineageInterleukin (IL)-32β-mediated CCAAT/enhancer-binding protein α (C/EBPα) phosphorylation by protein kinase Cδ (PKCδ) abrogates the inhibitory effect of C/EBPα on IL-10 productionRepression of transcriptional activity of C/EBPalpha by E2F-dimerization partner complexesThe CCAAT enhancer-binding protein alpha (C/EBPalpha) requires a SWI/SNF complex for proliferation arrestIn prostate cancer cells the interaction of C/EBPalpha with Ku70, Ku80, and poly(ADP-ribose) polymerase-1 increases sensitivity to DNA damageLEF-1 is crucial for neutrophil granulocytopoiesis and its expression is severely reduced in congenital neutropeniaLiver tumors escape negative control of proliferation via PI3K/Akt-mediated block of C/EBP alpha growth inhibitory activityUse of chromatin immunoprecipitation to clone novel E2F target promotersPrevalence and prognostic implications of CEBPA mutations in pediatric acute myeloid leukemia (AML): a report from the Children's Oncology GroupUpstream open reading frames: molecular switches in (patho)physiologyCell-cycle regulator E2F1 and microRNA-223 comprise an autoregulatory negative feedback loop in acute myeloid leukemiaPerspectives of differentiation therapies of acute myeloid leukemia: the search for the molecular basis of patients' variable responses to 1,25-dihydroxyvitamin d and vitamin d analogsStructural basis for DNA recognition by the basic region leucine zipper transcription factor CCAAT/enhancer-binding protein alphaPrognostic implications of CEBPA mutations in pediatric acute myeloid leukemia: a report from the Japanese Pediatric Leukemia/Lymphoma Study GroupTranscriptional inhibition of interleukin-8 expression in tumor necrosis factor-tolerant cells: evidence for involvement of C/EBP betaPak2 regulates hematopoietic progenitor cell proliferation, survival, and differentiationSumoylation of CCAAT/enhancer-binding protein alpha and its functional roles in hepatocyte differentiationDown regulation of PSA by C/EBPalpha is associated with loss of AR expression and inhibition of PSA promoter activity in the LNCaP cell lineLoss of C/EBP alpha cell cycle control increases myeloid progenitor proliferation and transforms the neutrophil granulocyte lineageIdentification of a myeloid committed progenitor as the cancer-initiating cell in acute promyelocytic leukemia.Comprehensive genomic screens identify a role for PLZF-RARalpha as a positive regulator of cell proliferation via direct regulation of c-MYCSox4 is a key oncogenic target in C/EBPα mutant acute myeloid leukemiaIdentification of nuclear-enriched miRNAs during mouse granulopoiesisDisruption of the C/EBPα-miR-182 balance impairs granulocytic differentiation.C/EBPbeta cooperates with RB:E2F to implement Ras(V12)-induced cellular senescence.The identification of E2F1-specific target genesInnate immune regulation by STAT-mediated transcriptional mechanisms.Elevated PIN1 expression by C/EBPalpha-p30 blocks C/EBPalpha-induced granulocytic differentiation through c-Jun in AMLConstitutive MAP kinase activation in hematopoietic stem cells induces a myeloproliferative disorder.STAT3 controls myeloid progenitor growth during emergency granulopoiesis.MYC-regulated genes involved in liver cell dysplasia identified in a transgenic model of liver cancer.Respiratory failure due to differentiation arrest and expansion of alveolar cells following lung-specific loss of the transcription factor C/EBPalpha in mice.Role of pescadillo and upstream binding factor in the proliferation and differentiation of murine myeloid cells.C/EBPdelta expression in a BCR-ABL-positive cell line induces growth arrest and myeloid differentiation.CEBPA point mutations in hematological malignancies.Pharmacological targeting of miR-155 via the NEDD8-activating enzyme inhibitor MLN4924 (Pevonedistat) in FLT3-ITD acute myeloid leukemia.The multifaceted functions of C/EBPα in normal and malignant haematopoiesis.C/EBPα regulated microRNA-34a targets E2F3 during granulopoiesis and is down-regulated in AML with CEBPA mutationsProteomic discovery of Max as a novel interacting partner of C/EBPalpha: a Myc/Max/Mad link.
P2860
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P2860
c-Myc is a critical target for c/EBPalpha in granulopoiesis.
description
2001 nî lūn-bûn
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2001 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունիսին հրատարակված գիտական հոդված
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2001年の論文
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2001年学术文章
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2001年学术文章
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2001年学术文章
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2001年学术文章
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2001年学术文章
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2001年學術文章
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name
c-Myc is a critical target for c/EBPalpha in granulopoiesis.
@ast
c-Myc is a critical target for c/EBPalpha in granulopoiesis.
@en
type
label
c-Myc is a critical target for c/EBPalpha in granulopoiesis.
@ast
c-Myc is a critical target for c/EBPalpha in granulopoiesis.
@en
prefLabel
c-Myc is a critical target for c/EBPalpha in granulopoiesis.
@ast
c-Myc is a critical target for c/EBPalpha in granulopoiesis.
@en
P2093
P2860
P1476
c-Myc is a critical target for c/EBPalpha in granulopoiesis
@en
P2093
P2860
P304
P356
10.1128/MCB.21.11.3789-3806.2001
P407
P577
2001-06-01T00:00:00Z