Full-length and truncated versions of the hepatitis B virus (HBV) X protein (pX) transactivate the cmyc protooncogene at the transcriptional level.
about
The X protein of hepatitis B virus binds to the F box protein Skp2 and inhibits the ubiquitination and proteasomal degradation of c-MycHepatitis B virus and microRNAs: Complex interactions affecting hepatitis B virus replication and hepatitis B virus-associated diseasesHepatitis B virus HBx protein sensitizes cells to apoptotic killing by tumor necrosis factor alphaUnderstanding the role of PIN1 in hepatocellular carcinomac-MYC-Making Liver Sick: Role of c-MYC in Hepatic Cell Function, Homeostasis and Disease.Hepatitis B virus HBx protein deregulates cell cycle checkpoint controlsNatural variants of hepatitis B virus X protein have differential effects on the expression of cyclin-dependent kinase inhibitor p21 gene.Role of NF-kappaB and myc proteins in apoptosis induced by hepatitis B virus HBx protein.Hepatitis B virus biology.Putative role of hepatitis B virus X protein in hepatocarcinogenesis: effects on apoptosis, DNA repair, mitogen-activated protein kinase and JAK/STAT pathways.Interaction of Hepatitis B virus with cellular processes in liver carcinogenesis.Modulation of miR-29 expression by α-fetoprotein is linked to the hepatocellular carcinoma epigenome.Targeting c-Myc as a novel approach for hepatocellular carcinoma.Targeting the PI3K/Akt/mTOR pathway in hepatocellular carcinoma.Hepatitis B virus transactivator protein X interacts with the TATA-binding protein.Hepatitis B virus X protein downregulates expression of the miR-16 family in malignant hepatocytes in vitro.Possible role of tocopherols in the modulation of host microRNA with potential antiviral activity in patients with hepatitis B virus-related persistent infection: a systematic review.The hepatitis B virus X gene induces p53-mediated programmed cell death.Activation of Src family kinases by hepatitis B virus HBx protein and coupled signaling to RasThe hepatitis B virus HBx protein is a dual specificity cytoplasmic activator of Ras and nuclear activator of transcription factors.A truncated mutant (residues 58-140) of the hepatitis B virus X protein retains transactivation function.Targeted therapy of hepatocellular cancer.Hepatitis B virus X gene and hepatocarcinogenesis.Molecular targeted therapy for hepatocellular carcinoma: current and future.An internal segment (residues 58-119) of the hepatitis B virus X protein is sufficient to activate MAP kinase pathways in mouse liver.Induction of the DNA-binding activity of c-jun/c-fos heterodimers by the hepatitis B virus transactivator pXLiver cell transformation in chronic HBV infection.c-Myc-mediated overexpression of miR-17-92 suppresses replication of hepatitis B virus in human hepatoma cells.The X protein of hepatitis B virus coactivates potent activation domains.Induction of cell cycle progression by hepatitis B virus HBx gene expression in quiescent mouse fibroblasts.Possible mechanism for hepatitis B virus X gene to induce apoptosis of hepatocytes.Hepatitis B virus X protein transactivates the inducible nitric oxide synthase promoter.The molecular pathogenesis of hepatocellular carcinoma.Hepatitis B virus transcriptional activators: mechanisms and possible role in oncogenesis.Small interfering RNA targeting CDC25B inhibits liver tumor growth in vitro and in vivoThe hepatitis B virus X-associated protein, XAP3, is a protein kinase C-binding protein.Long-term productive episomal hepatitis B virus replication in primary cultures of adult human hepatocytes infected in vitro.
P2860
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P2860
Full-length and truncated versions of the hepatitis B virus (HBV) X protein (pX) transactivate the cmyc protooncogene at the transcriptional level.
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
1991年论文
@zh
1991年论文
@zh-cn
name
Full-length and truncated vers ...... at the transcriptional level.
@en
type
label
Full-length and truncated vers ...... at the transcriptional level.
@en
prefLabel
Full-length and truncated vers ...... at the transcriptional level.
@en
P2093
P1476
Full-length and truncated vers ...... at the transcriptional level.
@en
P2093
P304
P356
10.1016/0006-291X(91)90379-L
P577
1991-05-01T00:00:00Z