Mechanism of activation and function of protein kinase B.
about
Characterization of the structure and regulation of two novel isoforms of serum- and glucocorticoid-induced protein kinasePotential role of 3-phosphoinositide-dependent protein kinase 1 (PDK1) in insulin-stimulated glucose transporter 4 translocation in adipocytesLithium: the pharmacodynamic actions of the amazing ionDifferential regulation of the phosphatidylinositol 3-kinase/Akt and p70 S6 kinase pathways by the alpha(1A)-adrenergic receptor in rat-1 fibroblastsRoles of the forkhead in rhabdomyosarcoma (FKHR) phosphorylation sites in regulating 14-3-3 binding, transactivation and nuclear targettingScribble-mediated membrane targeting of PHLPP1 is required for its negative regulation of AktCaspase-3-mediated cleavage of Akt: involvement of non-consensus sites and influence of phosphorylationKinetic mechanism of AKT/PKB enzyme familyEssential function of TORC2 in PKC and Akt turn motif phosphorylation, maturation and signallingInsulin-stimulated phosphorylation of lipin mediated by the mammalian target of rapamycin.Activation of serum- and glucocorticoid-regulated protein kinase by agonists that activate phosphatidylinositide 3-kinase is mediated by 3-phosphoinositide-dependent protein kinase-1 (PDK1) and PDK2Two novel phosphorylation sites on FKHR that are critical for its nuclear exclusionIRS-4 mediates protein kinase B signaling during insulin stimulation without promoting antiapoptosisTherapeutic potential of mood stabilizers lithium and valproic acid: beyond bipolar disorderNegative regulation of PI 3-kinase by Ruk, a novel adaptor proteinDAF-16 recruits the CREB-binding protein coactivator complex to the insulin-like growth factor binding protein 1 promoter in HepG2 cellsAlzheimer's Disease: Mechanism and Approach to Cell TherapyThe molecular basis for load-induced skeletal muscle hypertrophyBinding of phosphatidylinositol 3,4,5-trisphosphate to the pleckstrin homology domain of protein kinase B induces a conformational changeAn ATP-site on-off switch that restricts phosphatase accessibility of AktRegulation of the rapamycin and FKBP-target 1/mammalian target of rapamycin and cap-dependent initiation of translation by the c-Abl protein-tyrosine kinaseRho GTPase control of protein kinase C-related protein kinase activation by 3-phosphoinositide-dependent protein kinaseA 3-phosphoinositide-dependent protein kinase-1 (PDK1) docking site is required for the phosphorylation of protein kinase Czeta (PKCzeta ) and PKC-related kinase 2 by PDK1Cloning and characterization of a nuclear S6 kinase, S6 kinase-related kinase (SRK); a novel nuclear target of AktThe Src homology 2 domain containing inositol 5-phosphatase SHIP2 is recruited to the epidermal growth factor (EGF) receptor and dephosphorylates phosphatidylinositol 3,4,5-trisphosphate in EGF-stimulated COS-7 cellsCalmodulin binds to K-Ras, but not to H- or N-Ras, and modulates its downstream signalingRole of Gab proteins in phosphatidylinositol 3-kinase activation by thrombopoietin (Tpo)Akt (protein kinase B) negatively regulates SEK1 by means of protein phosphorylationInvolvement of phosphatidylinositol 3-kinase, but not RalGDS, in TC21/R-Ras2-mediated transformationHeregulin-dependent activation of phosphoinositide 3-kinase and Akt via the ErbB2/ErbB3 co-receptorRole of Fas-associated death domain-containing protein (FADD) phosphorylation in regulating glucose homeostasis: from proteomic discovery to physiological validationCellular stress in xenopus kidney cells enhances the phosphorylation of eukaryotic translation initiation factor (eIF)4E and the association of eIF4F with poly(A)-binding proteinGrowth retardation and increased apoptosis in mice with homozygous disruption of the Akt1 geneTumour necrosis factor-alpha activation of protein kinase B in WEHI-164 cells is accompanied by increased phosphorylation of Ser473, but not Thr308Characterization of the Akt2 domain essential for binding nuclear p21cip1 to promote cell cycle arrest during myogenic differentiationHyperinsulinemia: effect on cardiac mass/function, angiotensin II receptor expression, and insulin signaling pathwaysInsulin promotes the cell surface recruitment of the SAT2/ATA2 system A amino acid transporter from an endosomal compartment in skeletal muscle cellsNovel inositol polyphosphate 5-phosphatase localizes at membrane rufflesZNRF1 promotes Wallerian degeneration by degrading AKT to induce GSK3B-dependent CRMP2 phosphorylationThe role of Asp-462 in regulating Akt activity
P2860
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P2860
Mechanism of activation and function of protein kinase B.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Mechanism of activation and function of protein kinase B.
@en
type
label
Mechanism of activation and function of protein kinase B.
@en
prefLabel
Mechanism of activation and function of protein kinase B.
@en
P1476
Mechanism of activation and function of protein kinase B
@en
P2093
P356
10.1016/S0959-437X(98)80062-2
P577
1998-02-01T00:00:00Z