The colony stimulating factor-1 receptor associates with and activates phosphatidylinositol-3 kinase.
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Tyrosine mutations within the alpha platelet-derived growth factor receptor kinase insert domain abrogate receptor-associated phosphatidylinositol-3 kinase activity without affecting mitogenic or chemotactic signal transductionActivation of Src family kinases by colony stimulating factor-1, and their association with its receptorHuman homologue of the Drosophila discs large tumor suppressor binds to p56lck tyrosine kinase and Shaker type Kv1.3 potassium channel in T lymphocytesPhosphorylation sites in the PDGF receptor with different specificities for binding GAP and PI3 kinase in vivoInteraction of the p85 subunit of PI 3-kinase and its N-terminal SH2 domain with a PDGF receptor phosphorylation site: structural features and analysis of conformational changesExpression and characterization of the p85 subunit of the phosphatidylinositol 3-kinase complex and a related p85 beta protein by using the baculovirus expression systemActivation of Src-like protein-tyrosine kinase Lyn and its association with phosphatidylinositol 3-kinase upon B-cell antigen receptor-mediated signalingEps8, a substrate for the epidermal growth factor receptor kinase, enhances EGF-dependent mitogenic signalsInteractions of phosphatidylinositol kinase, GTPase-activating protein (GAP), and GAP-associated proteins with the colony-stimulating factor 1 receptorDirect association of p110 beta phosphatidylinositol 3-kinase with p85 is mediated by an N-terminal fragment of p110 betaCloning of a novel, ubiquitously expressed human phosphatidylinositol 3-kinase and identification of its binding site on p85Activation and association of Stat3 with Src in v-Src-transformed cell linesRegulation of osteoclasts by membrane-derived lipid mediatorsPurification and characterization of the phosphatidylinositol-3,4,5-trisphosphate phosphatase in bovine thymusDirect association of Grb2 with the p85 subunit of phosphatidylinositol 3-kinaseSequence requirements for binding of Src family tyrosine kinases to activated growth factor receptorsMutation of Tyr697, a GRB2-binding site, and Tyr721, a PI 3-kinase binding site, abrogates signal transduction by the murine CSF-1 receptor expressed in Rat-2 fibroblastsGrowth factor-induced tyrosine phosphorylation of Hrs, a novel 115-kilodalton protein with a structurally conserved putative zinc finger domainThe erbB-2 mitogenic signaling pathway: tyrosine phosphorylation of phospholipase C-gamma and GTPase-activating protein does not correlate with erbB-2 mitogenic potencyInteractions of phosphatidylinositol 3-kinase Src homology 3 domain with its ligand peptide studied by absorption, circular dichroism, and UV resonance raman spectroscopies.Stimulation of human monocytes with macrophage colony-stimulating factor induces a Grb2-mediated association of the focal adhesion kinase pp125FAK and dynaminThe v-Src SH3 domain binds phosphatidylinositol 3'-kinase.1H and 15N assignments and secondary structure of the PI3K SH3 domain.Structure of 85 kDa subunit of human phosphatidylinositol 3-kinase analyzed by using monoclonal antibodies.Mutations in the SH3 domain of the src oncogene which decrease association of phosphatidylinositol 3'-kinase activity with pp60v-src and alter cellular morphology.Interleukin 2- and polyomavirus middle T antigen-induced modification of phosphatidylinositol 3-kinase activity in activated T lymphocytes.Tyrosine 807 of the v-Fms oncogene product controls cell morphology and association with p120RasGAP.The first long-lived mutants: discovery of the insulin/IGF-1 pathway for ageingPI3K p110γ deletion attenuates murine atherosclerosis by reducing macrophage proliferation but not polarization or apoptosis in lesions.Interaction of phosphatidylinositol 3-kinase-associated p85 with epidermal growth factor and platelet-derived growth factor receptorsActivated type I phosphatidylinositol kinase is associated with the epidermal growth factor (EGF) receptor following EGF stimulationCKIP-1 regulates macrophage proliferation by inhibiting TRAF6-mediated Akt activationA point mutation at tyrosine-809 in the human colony-stimulating factor 1 receptor impairs mitogenesis without abrogating tyrosine kinase activity, association with phosphatidylinositol 3-kinase, or induction of c-fos and junB genes.Sequential activation of phoshatidylinositol 3-kinase and phospholipase C-gamma2 by the M-CSF receptor is necessary for differentiation signalingActivation of phosphatidylinositol-3 kinase by ligation of the interleukin-7 receptor on human thymocytes.Thrombin-stimulated immunoprecipitation of phosphatidylinositol 3-kinase from human platelets.Phosphorylation of the PDGF receptor beta subunit creates a tight binding site for phosphatidylinositol 3 kinasePhorbol ester treatment inhibits phosphatidylinositol 3-kinase activation by, and association with, CD28, a T-lymphocyte surface receptorTyr721 regulates specific binding of the CSF-1 receptor kinase insert to PI 3'-kinase SH2 domains: a model for SH2-mediated receptor-target interactionsMacrophage colony stimulating factor activates phosphatidylcholine hydrolysis by cytoplasmic phospholipase A2.
P2860
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P2860
The colony stimulating factor-1 receptor associates with and activates phosphatidylinositol-3 kinase.
description
1989 nî lūn-bûn
@nan
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
1989年论文
@zh
1989年论文
@zh-cn
name
The colony stimulating factor- ...... phosphatidylinositol-3 kinase.
@en
type
label
The colony stimulating factor- ...... phosphatidylinositol-3 kinase.
@en
prefLabel
The colony stimulating factor- ...... phosphatidylinositol-3 kinase.
@en
P2093
P356
P1433
P1476
The colony stimulating factor- ...... phosphatidylinositol-3 kinase.
@en
P2093
D Morrison
L Varticovski
P2888
P304
P356
10.1038/342699A0
P407
P577
1989-12-01T00:00:00Z
P6179
1022754900