A fungal ketoreductase domain that displays substrate-dependent stereospecificity.
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Recent Advances in Understanding and Engineering Polyketide SynthesisStructural and functional studies of atrans-acyltransferase polyketide assembly line enzyme that catalyzes stereoselective α- and β-ketoreductionCharacterization of the biosynthetic genes for 10,11-dehydrocurvularin, a heat shock response-modulating anticancer fungal polyketide from Aspergillus terreusBiochemical and Structural Basis for Controlling Chemical Modularity in Fungal Polyketide BiosynthesisInsights into the biosynthesis of 12-membered resorcylic acid lactones from heterologous production in Saccharomyces cerevisiae.Diversity-oriented combinatorial biosynthesis of benzenediol lactone scaffolds by subunit shuffling of fungal polyketide synthases.Hirsutellones and beyond: figuring out the biological and synthetic logics toward chemical complexity in fungal PKS-NRPS compounds.Substrate control in stereoselective lanthionine biosynthesis.Methylation-dependent acyl transfer between polyketide synthase and nonribosomal peptide synthetase modules in fungal natural product biosynthesis.Enediyne polyketide synthases stereoselectively reduce the β-ketoacyl intermediates to β-D-hydroxyacyl intermediates in enediyne core biosynthesis.Recent progress regarding the bioactivities, biosynthesis and synthesis of naturally occurring resorcinolic macrolides.Characterization of a fungal thioesterase having Claisen cyclase and deacetylase activities in melanin biosynthesis.Investigation of fungal iterative polyketide synthase functions using partially assembled intermediates.Rational reprogramming of fungal polyketide first-ring cyclizationThioesterase domains of fungal nonreducing polyketide synthases act as decision gates during combinatorial biosynthesis.Structural analysis of protein-protein interactions in type I polyketide synthasesHuman amniotic epithelial cells can differentiate into granulosa cells and restore folliculogenesis in a mouse model of chemotherapy-induced premature ovarian failure.The structures of type I polyketide synthases.Strategies for mining fungal natural products.Bioinformatics tools for genome mining of polyketide and non-ribosomal peptides.Explorations of fungal biosynthesis of reduced polyketides - a personal viewpoint.Polyketide synthase and non-ribosomal peptide synthetase thioesterase selectivity: logic gate or a victim of fate?Reconstruction of the biosynthetic pathway for the core fungal polyketide scaffold rubrofusarin in Saccharomyces cerevisiaeSubstrate-Determined Diastereoselectivity in an Enzymatic Carboligation.Navigating the fungal polyketide chemical space: from genes to molecules.A trans-acting ketoreductase in biosynthesis of a symmetric polyketide dimer SIA7248.Dess-Martin periodinane oxidative rearrangement for preparation of α-keto thioesters.Addition of a polyhistidine tag alters the regioselectivity of carbonyl reductase S1 from Candida magnoliae.Substrate-dependent stereospecificity of Tyl-KR1: an isolated polyketide synthase ketoreductase domain from Streptomyces fradiae.Insights into the programmed ketoreduction of partially reducing polyketide synthases: stereo- and substrate-specificity of the ketoreductase domain
P2860
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P2860
A fungal ketoreductase domain that displays substrate-dependent stereospecificity.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
A fungal ketoreductase domain that displays substrate-dependent stereospecificity.
@en
type
label
A fungal ketoreductase domain that displays substrate-dependent stereospecificity.
@en
prefLabel
A fungal ketoreductase domain that displays substrate-dependent stereospecificity.
@en
P2093
P2860
P356
P1476
A fungal ketoreductase domain that displays substrate-dependent stereospecificity.
@en
P2093
Jingjing Wang
Kangjian Qiao
Zhizeng Gao
P2860
P2888
P304
P356
10.1038/NCHEMBIO.912
P577
2012-03-11T00:00:00Z
P5875
P6179
1018236472