Exploring the Requirements for the Hydrophobic Scaffold and Polar Amine in inhibitors of M2 from Influenza A Virus.
about
Recent progress in structure-based anti-influenza drug designStructure and inhibition of the drug-resistant S31N mutant of the M2 ion channel of influenza A virusInhibitors of the influenza A virus M2 proton channel discovered using a high-throughput yeast growth restoration assayFlipping in the pore: discovery of dual inhibitors that bind in different orientations to the wild-type versus the amantadine-resistant S31N mutant of the influenza A virus M2 proton channel.Watching Proteins Wiggle: Mapping Structures with Two-Dimensional Infrared Spectroscopy.Discovery of novel dual inhibitors of the wild-type and the most prevalent drug-resistant mutant, S31N, of the M2 proton channel from influenza A virus.Detection of proton movement directly across viral membranes to identify novel influenza virus M2 inhibitors.Viral miniproteinsHydrogen-bonded water molecules in the M2 channel of the influenza A virus guide the binding preferences of ammonium-based inhibitors.Discovery of Highly Potent Inhibitors Targeting the Predominant Drug-Resistant S31N Mutant of the Influenza A Virus M2 Proton Channel.On the role of water density fluctuations in the inhibition of a proton channelExploring organosilane amines as potent inhibitors and structural probes of influenza a virus M2 proton channel.Slow but Steady Wins the Race: Dissimilarities among New Dual Inhibitors of the Wild-Type and the V27A Mutant M2 Channels of Influenza A Virus.Isocyanides as Influenza A Virus Subtype H5N1 Wild-Type M2 Channel Inhibitors.
P2860
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P2860
Exploring the Requirements for the Hydrophobic Scaffold and Polar Amine in inhibitors of M2 from Influenza A Virus.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Exploring the Requirements for ...... of M2 from Influenza A Virus.
@en
type
label
Exploring the Requirements for ...... of M2 from Influenza A Virus.
@en
prefLabel
Exploring the Requirements for ...... of M2 from Influenza A Virus.
@en
P2093
P2860
P356
P1476
Exploring the Requirements for ...... of M2 from Influenza A Virus.
@en
P2093
Chunlong Ma
Lawrence H Pinto
Robert A Lamb
Victoria Balannik
William F Degrado
P2860
P304
P356
10.1021/ML100297W
P50
P577
2011-04-01T00:00:00Z