Angiogenesis selectively requires the p110alpha isoform of PI3K to control endothelial cell migration.
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PI3K/AKT/mTOR Pathway in AngiogenesisA phosphodiesterase 3B-based signaling complex integrates exchange protein activated by cAMP 1 and phosphatidylinositol 3-kinase signals in human arterial endothelial cellsShould individual PI3 kinase isoforms be targeted in cancer?Cardiac regulation by phosphoinositide 3-kinases and PTENSemaphorin-PlexinD1 signaling limits angiogenic potential via the VEGF decoy receptor sFlt1miR-221 is required for endothelial tip cell behaviors during vascular developmentHuman miR-221/222 in Physiological and Atherosclerotic Vascular RemodelingTargeting p110gamma in gastrointestinal cancers: attack on multiple frontsPhosphoinositides: tiny lipids with giant impact on cell regulationStability and function of adult vasculature is sustained by Akt/Jagged1 signalling axis in endothelium.Tipping the balance: robustness of tip cell selection, migration and fusion in angiogenesisTargeted polypharmacology: discovery of dual inhibitors of tyrosine and phosphoinositide kinasesThe p110α and p110β isoforms of PI3K play divergent roles in mammary gland development and tumorigenesis.Somatic Activating PIK3CA Mutations Cause Venous MalformationSignaling by the phosphoinositide 3-kinase family in immune cellsPI3K/PTEN signaling in angiogenesis and tumorigenesisMultimodal microvascular imaging reveals that selective inhibition of class I PI3K is sufficient to induce an antivascular responsePI3K at the crossroads of tumor angiogenesis signaling pathwaysSelective inhibition of retinal angiogenesis by targeting PI3 kinaseTemsirolimus inhibits proliferation and migration in retinal pigment epithelial and endothelial cells via mTOR inhibition and decreases VEGF and PDGF expressionNovel Role for p110β PI 3-Kinase in Male Fertility through Regulation of Androgen Receptor Activity in Sertoli CellsBJ-1108, a 6-Amino-2,4,5-Trimethylpyridin-3-ol Analog, Inhibits Serotonin-Induced Angiogenesis and Tumor Growth through PI3K/NOX PathwayVascular endothelial growth factor participates in modulating the C6 glioma-induced migration of rat bone marrow-derived mesenchymal stem cells and upregulates their vascular cell adhesion molecule-1 expressionInhibition of phosphatidylinositol 3-kinase/Akt signaling attenuates hypoxia-induced pulmonary artery remodeling and suppresses CREB depletion in arterial smooth muscle cellsRas is an indispensable coregulator of the class IB phosphoinositide 3-kinase p87/p110gammaA computational tool for quantitative analysis of vascular networksTargeting PI3K in cancer: impact on tumor cells, their protective stroma, angiogenesis and immunotherapyPI3K pathway alterations in cancer: variations on a themeTargeting the phosphoinositide 3-kinase pathway in cancerArterial-venous segregation by selective cell sprouting: an alternative mode of blood vessel formation.Nuclear phosphoinositide 3-kinase beta controls double-strand break DNA repair.The embryonic mouse hindbrain as a qualitative and quantitative model for studying the molecular and cellular mechanisms of angiogenesisDynamic responses of endothelial cells to changes in blood flow during vascular remodeling of the mouse yolk sac.Dll4-containing exosomes induce capillary sprout retraction in a 3D microenvironmentThe p110δ isoform of the kinase PI(3)K controls the subcellular compartmentalization of TLR4 signaling and protects from endotoxic shock.KIF13B regulates angiogenesis through Golgi to plasma membrane trafficking of VEGFR2Physical supports from liver cancer cells are essential for differentiation and remodeling of endothelial cells in a HepG2-HUVEC co-culture model.A Rac/Cdc42 exchange factor complex promotes formation of lateral filopodia and blood vessel lumen morphogenesisPI3K p110δ uniquely promotes gain-of-function Shp2-induced GM-CSF hypersensitivity in a model of JMML.Klotho ameliorates oxidized low density lipoprotein (ox-LDL)-induced oxidative stress via regulating LOX-1 and PI3K/Akt/eNOS pathways
P2860
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P2860
Angiogenesis selectively requires the p110alpha isoform of PI3K to control endothelial cell migration.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Angiogenesis selectively requi ...... ol endothelial cell migration.
@en
type
label
Angiogenesis selectively requi ...... ol endothelial cell migration.
@en
prefLabel
Angiogenesis selectively requi ...... ol endothelial cell migration.
@en
P2093
P50
P921
P356
P1433
P1476
Angiogenesis selectively requi ...... rol endothelial cell migration
@en
P2093
Andrew J H Smith
Ashreena Salpekar
Bart Vanhaesebroeck
Lazaros C Foukas
Li-Kun Phng
Pedro R Cutillas
Robert J Cain
Stephen Meek
Wayne Pearce
P2888
P304
P356
10.1038/NATURE06892
P407
P50
P577
2008-04-30T00:00:00Z
P5875
P6179
1029723170