Deamidation accelerates amyloid formation and alters amylin fiber structure
about
Causative factors for formation of toxic islet amyloid polypeptide oligomer in type 2 diabetes mellitusMechanisms of islet amyloidosis toxicity in type 2 diabetesInsight of brain degenerative protein modifications in the pathology of neurodegeneration and dementia by proteomic profilingWatching Proteins Wiggle: Mapping Structures with Two-Dimensional Infrared Spectroscopy.Post-translational modifications in PrP expand the conformational diversity of prions in vivoHeat-induced irreversible denaturation of the camelid single domain VHH antibody is governed by chemical modifications.Detection of Helical Intermediates During Amyloid Formation by Intrinsically Disordered Polypeptides and Proteins.In Vitro Studies of Membrane Permeability Induced by Amyloidogenic Polypeptides Using Large Unilamellar Vesicles.Deamidation reactions of protonated asparagine and glutamine investigated by ion spectroscopy.Deamidation Reactions of Asparagine- and Glutamine-Containing Dipeptides Investigated by Ion Spectroscopy.Islet Amyloid Polypeptide: Structure, Function, and Pathophysiology.Asparagine deamidation reduces DNA-binding affinity of the Drosophila melanogaster Scr homeodomain.Dementia-linked amyloidosis is associated with brain protein deamidation as revealed by proteomic profiling of human brain tissues.A strongly absorbing class of non-natural labels for probing protein electrostatics and solvation with FTIR and 2D IR spectroscopies.Lessons from two prevalent amyloidoses-what amylin and Aβ have in commonIntrinsic structural heterogeneity and long-term maturation of amyloid β peptide fibrilsIslet amyloid: from fundamental biophysics to mechanisms of cytotoxicity.Amyloid fiber formation in human γD-Crystallin induced by UV-B photodamageAggregation of islet amyloid polypeptide: from physical chemistry to cell biology.Protein truncation as a common denominator of human neurodegenerative foldopathies.Early engineering approaches to improve peptide developability and manufacturability.Future of the Genetic Code.Structural Properties of Human IAPP Dimer in Membrane Environment Studied by All-Atom Molecular Dynamics Simulations.Suppression of amyloid fibrils using the GroEL apical domain.An alternative structural isoform in amyloid-like aggregates formed from thermally denatured human γD-crystallin.How to Get Insight into Amyloid Structure and Formation from Infrared Spectroscopy.L-Asparagine crystals with wide gap semiconductor features: optical absorption measurements and density functional theory computations.Factors affecting the physical stability (aggregation) of peptide therapeutics.Islet Amyloid Polypeptide Membrane Interactions: Effects of Membrane Composition.Deamidation of Protonated Asparagine-Valine Investigated by a Combined Spectroscopic, Guided Ion Beam, and Theoretical Study.Isotope-Labeled Amyloids via Synthesis, Expression, and Chemical Ligation for Use in FTIR, 2D IR, and NMR Studies.Transition Dipoles from 1D and 2D Infrared Spectroscopy Help Reveal the Secondary Structures of Proteins: Application to Amyloids.Understanding amyloid fibril formation using protein fragments: structural investigations via vibrational spectroscopy and solid-state NMRImplications of Metal Binding and Asparagine Deamidation for Amyloid Formation
P2860
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P2860
Deamidation accelerates amyloid formation and alters amylin fiber structure
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Deamidation accelerates amyloid formation and alters amylin fiber structure
@en
type
label
Deamidation accelerates amyloid formation and alters amylin fiber structure
@en
prefLabel
Deamidation accelerates amyloid formation and alters amylin fiber structure
@en
P2093
P2860
P356
P1476
Deamidation accelerates amyloid formation and alters amylin fiber structure
@en
P2093
Emily B Dunkelberger
Martin T Zanni
Peter Marek
P2860
P304
12658-12667
P356
10.1021/JA3039486
P407
P577
2012-07-17T00:00:00Z