Restriction specificities, alloreactivity, and allotolerance expressed by T cells from nude mice reconstituted with H-2-compatible or -incompatible thymus grafts
about
A lung-specific neo-antigen elicits specific CD8+ T cell tolerance with preserved CD4+ T cell reactivity. Implications for immune-mediated lung disease.Self recognition in allogeneic thymic chimeras. Self recognition by T helper cells from thymus-engrafted nude mice is restricted to the thymic H-2 haplotype.Efficient T cell repertoire selection in tetraparental chimeric mice independent of thymic epithelial MHCUncertainties - discrepancies in immunology.Thymic selection revisited: how essential is it?Functional CD8+ but not CD4+ T cell responses develop independent of thymic epithelial MHC.On 'reactivity' versus 'tolerance'.Class II-positive hematopoietic cells cannot mediate positive selection of CD4+ T lymphocytes in class II-deficient miceFunctional T cells in athymic nude miceSendai virus-specific, H-2-restricted cytotoxic T lymphocyte responses of nude mice grafted with allogeneic or semi-allogeneic thymus glands.Cytotoxic T lymphocyte responses by chimeric thymocytes. Self-recognition is determined early in T cell development.Frequency analysis of cytotoxic T lymphocyte precursors in chimeric mice. Evidence for intrathymic maturation of clonally distinct self-major histocompatibility complex- and allo-major histocompatiblilty complex-restricted virus-specific T cells.Committed T lymphocyte stem cells of rats. Characterization by surface W3/13 antigen and radiosensitivityGenetic control of the immune response to myoglobins. Both low and high responder T cells tolerant to the other major histocompatibility complex help high but not low responder B cells.Induction of neonatal tolerance to H-2k in B6 mice does not allow the emergence of T cells specific for H-2k plus vaccinia virus.Tpre, a new alloantigen encoded in the IgT-C region of chromosome 12, is expressed on bone marrow of nude mice, fetal T cell hybrids, and fetal thymus.Thymus dictates major histocompatibility complex (MHC) specificity and immune response gene phenotype of class II MHC-restricted T cells but not of class I MHC-restricted T cells.Cells expressing Ia antigens in the avian thymus.Distinct fates of self-specific T cells developing in irradiation bone marrow chimeras: clonal deletion, clonal anergy, or in vitro responsiveness to self-Mls-1a controlled by hemopoietic cells in the thymusAntigen recognition by MHC-incompatible cells of a human mismatched chimera.The concurrent maturation of mouse and human thymocytes in human fetal thymus implanted in NIH-beige-nude-xid mice is associated with the reconstitution of the murine immune systemInfluence of H-2 antigen expression on killer T cell specificity, differentiation, and induction.T-cell development: an extrathymic perspective.On the role of thymic epithelium vs. bone marrow-derived cells in repertoire selection of T cells.H-2 restriction as a consequence of intentional priming: T cells of fully allogeneic chimeric mice as well as of normal mice respond to foreign antigens in the context of H-2 determinants not encountered on thymic epithelial cellsTolerance to MHC class II disparate allografts through genetic modification of bone marrow.T and B cell tolerance and responses to viral antigens in transgenic mice: implications for the pathogenesis of autoimmune versus immunopathological disease.Self recognition by the immune system.T cell selection in the thymus.Significance of self-recognition and interleukin-2 for immunoregulation, autoimmunity and cancer.Ontogeny of primary lymphoid organs and lymphoid stem cells.T cells, the MHC, and function.Impact of thymus on the generation of immunocompetence and diversity of antigen-specific MHC-restricted cytotoxic T-lymphocyte precursors.Incomplete tolerance to MHC antigens in irradiation chimeras: implications for MHC restriction and self tolerance.Development and loss of virus-specific thymic competence in bone marrow radiation chimeras and normal mice.The identity of the cells that positively select thymocytes.Positive selection of immature alpha beta T cells.Survival of mature CD4 T lymphocytes is dependent on major histocompatibility complex class II-expressing dendritic cells.Unusual cytotoxic activities of thymus-independent, self-antigen-specific CD8(+) T cells.Thymic microenvironment reconstitution after postnatal human thymus transplantation.
P2860
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P2860
Restriction specificities, alloreactivity, and allotolerance expressed by T cells from nude mice reconstituted with H-2-compatible or -incompatible thymus grafts
description
1980 nî lūn-bûn
@nan
1980年の論文
@ja
1980年論文
@yue
1980年論文
@zh-hant
1980年論文
@zh-hk
1980年論文
@zh-mo
1980年論文
@zh-tw
1980年论文
@wuu
1980年论文
@zh
1980年论文
@zh-cn
name
Restriction specificities, all ...... or -incompatible thymus grafts
@en
type
label
Restriction specificities, all ...... or -incompatible thymus grafts
@en
prefLabel
Restriction specificities, all ...... or -incompatible thymus grafts
@en
P2093
P2860
P356
P1476
Restriction specificities, all ...... or -incompatible thymus grafts
@en
P2093
Callahan G
Waterfield E
Zinkernagel RM
P2860
P304
P356
10.1084/JEM.151.2.376
P407
P577
1980-02-01T00:00:00Z