Insulin-like growth factor (IGF)-binding proteins inhibit the biological activities of IGF-1 and IGF-2 but not des-(1-3)-IGF-1.
about
Altered affinity of insulin-like growth factor II (IGF-II) for receptors and IGF-binding proteins, resulting from limited modifications of the IGF-II moleculeDesign and characterisation of long-R3-insulin-like growth factor-I muteins which show resistance to pepsin digestion.Characteristics of binding of insulin-like growth factor (IGF)-I and IGF-II analogues to the type 1 IGF receptor determined by BIAcore analysis.Insulin-like growth factor 1 physiology: lessons from mouse models.Insulin-like growth factor-I regulation of immune function: a potential therapeutic target in autoimmune diseases?Vitreous levels of the insulin-like growth factors I and II, and the insulin-like growth factor binding proteins 2 and 3, increase in neovascular eye disease. Studies in nondiabetic and diabetic subjectsInsulin-like growth factors I and II.Unbound (bioavailable) IGF1 enhances somatic growth.Granulosa cell-derived insulin-like growth factor (IGF) binding proteins are inhibitory to IGF-I hormonal action. Evidence derived from the use of a truncated IGF-I analogueHydroxy-terminated conjugated polymer nanoparticles have near-unity bright fraction and reveal cholesterol-dependence of IGF1R nanodomains.Effects of insulin-like growth factor binding proteins in bone -- a matter of cell and site.A (selective) history of Australian involvement in cytokine biology.Bioactivity of glomerular ultrafiltrate during heavy proteinuria may contribute to renal tubulo-interstitial lesions: evidence for a role for insulin-like growth factor I.Interaction between the insulin-like growth factor family and the integrin receptor family in tissue repair processes. Evidence in a rabbit ear dermal ulcer model.Protease-resistant form of insulin-like growth factor-binding protein 5 is an inhibitor of insulin-like growth factor-I actions on porcine smooth muscle cells in culture.Mutants of human insulin-like growth factor II (IGF II). Expression and characterization of truncated IGF II and of two naturally occurring variants.Pregnancy-associated plasma protein (PAPP)-A expressed in the mammary gland controls epithelial cell proliferation and differentiation.Establishment and characterization of an immortomouse-derived odontoblast-like cell line to evaluate the effect of insulin-like growth factors on odontoblast differentiation.Serum from heifer calves treated with bovine growth hormone affects the rate of proliferation of C2C12 myogenic cells dependent on the plane of nutrition: the role of insulin-like growth factor-I and IGF-binding proteins-2 and -3.The biological role of truncated insulin-like growth factor-1 and the tripeptide GPE in the central nervous system.Insulin-like growth factor binding protein-3 and -5 are regulated by transforming growth factor-beta and retinoic acid in the human prostate adenocarcinoma cell line PC-3.Paracellular transport of insulin-like growth factor-I (IGF-I) across human umbilical vein endothelial cell monolayers.Insulin-like growth factor I stimulates degradation of an mRNA transcript encoding the 14 kDa ubiquitin-conjugating enzyme.Enhanced expression of dihydrofolate reductase by bovine kidney epithelial cells results in altered cell morphology, IGF-I responsiveness, and IGF binding protein-3 expression.Ligand-dependent inhibition of myoblast differentiation by overexpression of the type-1 insulin-like growth factor receptor.Insulin-like growth factor binding protein (IGFBP) inhibits IGF action on human osteosarcoma cells.Insulin-like growth factor (IGF)-II binding to IGF-binding proteins and IGF receptors is modified by deletion of the N-terminal hexapeptide or substitution of arginine for glutamate-6 in IGF-II.N-terminal deletion mutants of insulin-like growth factor-II (IGF-II) show Thr7 and Leu8 important for binding to insulin and IGF-I receptors and Leu8 critical for all IGF-II functions.Mutations in the B-domain of insulin-like growth factor-I influence the oxidative folding to yield products with modified biological propertiesIncreased weight gain, nitrogen retention and muscle protein synthesis following treatment of diabetic rats with insulin-like growth factor (IGF)-I and des(1-3)IGF-I.Optimization of the hydroxylamine cleavage of an expressed fusion protein to produce recombinant human insulin-like growth factor (IGF)-I.Increased activity of insulin-like growth factor-binding protein in human thyroid papillary cancer tissue.Solid Phase Synthesis of an Analogue of Insulin, A0:R glargine, That Exhibits Decreased Mitogenic Activity
P2860
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P2860
Insulin-like growth factor (IGF)-binding proteins inhibit the biological activities of IGF-1 and IGF-2 but not des-(1-3)-IGF-1.
description
1989 nî lūn-bûn
@nan
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
1989年论文
@zh
1989年论文
@zh-cn
name
Insulin-like growth factor (IG ...... IGF-2 but not des-(1-3)-IGF-1.
@en
type
label
Insulin-like growth factor (IG ...... IGF-2 but not des-(1-3)-IGF-1.
@en
prefLabel
Insulin-like growth factor (IG ...... IGF-2 but not des-(1-3)-IGF-1.
@en
P2093
P2860
P356
P1433
P1476
Insulin-like growth factor (IG ...... IGF-2 but not des-(1-3)-IGF-1.
@en
P2093
P2860
P304
P356
10.1042/BJ2580267
P407
P577
1989-02-01T00:00:00Z