Insulin-like growth factor (IGF)-II binding to IGF-binding proteins and IGF receptors is modified by deletion of the N-terminal hexapeptide or substitution of arginine for glutamate-6 in IGF-II.
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Structure of the IGF-binding domain of the insulin-like growth factor-binding protein-5 (IGFBP-5): implications for IGF and IGF-I receptor interactionsAlanine scanning of a putative receptor binding surface of insulin-like growth factor-IBinding sites and binding properties of binary and ternary complexes of insulin-like growth factor-II (IGF-II), IGF-binding protein-3, and acid-labile subunitNuclear targeting of IGF-1 receptor in orbital fibroblasts from Graves' disease: apparent role of ADAM17Characteristics of binding of insulin-like growth factor (IGF)-I and IGF-II analogues to the type 1 IGF receptor determined by BIAcore analysis.The quantitative and functional relation between insulin-like growth factor-I (IGF) and IGF-binding proteins during human osteoarthritis.Structural basis for the lower affinity of the insulin-like growth factors for the insulin receptor.Understanding the mechanism of insulin and insulin-like growth factor (IGF) receptor activation by IGF-II.Insulin-like growth factor (IGF) binding protein-5 blocks skeletal muscle differentiation by inhibiting IGF actionsInsulin-like growth factor-binding protein-5 inhibits osteoblast differentiation and skeletal growth by blocking insulin-like growth factor actions.Molecular interactions in the insulin-like growth factor (IGF) axis: a surface plasmon resonance (SPR) based biosensor study.BIAcore analysis of bovine insulin-like growth factor (IGF)-binding protein-2 identifies major IGF binding site determinants in both the amino- and carboxyl-terminal domains.Insulin-like growth factor-II is a substrate for dipeptidylpeptidase I (cathepsin C). Biological properties of the product.Probing Receptor Specificity by Sampling the Conformational Space of the Insulin-like Growth Factor II C-domain.Mutations in the B-domain of insulin-like growth factor-I influence the oxidative folding to yield products with modified biological propertiesIGFs stimulate zebrafish cell proliferation by activating MAP kinase and PI3-kinase-signaling pathways.Contribution of residues A54 and L55 of the human insulin-like growth factor-II (IGF-II) A domain to Type 2 IGF receptor binding specificity.Role of the IGF-II receptor in mediating acute, non-genomic effects of retinoids and IGF-II on keratinocyte cell death.Alanine screening mutagenesis establishes tyrosine 60 of bovine insulin-like growth factor binding protein-2 as a determinant of insulin-like growth factor binding.A Novel Binding Site for the Human Insulin-like Growth Factor-II (IGF-II)/Mannose 6-Phosphate Receptor on IGF-IIAn Investigation of the Ligand Binding Properties and Negative Cooperativity of Soluble Insulin-like Growth Factor ReceptorsThe Insulin-like Growth Factor (IGF) Binding Site of Bovine Insulin-like Growth Factor Binding Protein-2 (bIGFBP-2) Probed by Iodination
P2860
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P2860
Insulin-like growth factor (IGF)-II binding to IGF-binding proteins and IGF receptors is modified by deletion of the N-terminal hexapeptide or substitution of arginine for glutamate-6 in IGF-II.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年学术文章
@wuu
1993年学术文章
@zh-cn
1993年学术文章
@zh-hans
1993年学术文章
@zh-my
1993年学术文章
@zh-sg
1993年學術文章
@yue
1993年學術文章
@zh
1993年學術文章
@zh-hant
name
Insulin-like growth factor (IG ...... ine for glutamate-6 in IGF-II.
@en
type
label
Insulin-like growth factor (IG ...... ine for glutamate-6 in IGF-II.
@en
prefLabel
Insulin-like growth factor (IG ...... ine for glutamate-6 in IGF-II.
@en
P2093
P2860
P356
P1433
P1476
Insulin-like growth factor (IG ...... ine for glutamate-6 in IGF-II.
@en
P2093
P2860
P304
P356
10.1042/BJ2930713
P407
P478
293 ( Pt 3)
P577
1993-08-01T00:00:00Z