Liberation of SARS-CoV main protease from the viral polyprotein: N-terminal autocleavage does not depend on the mature dimerization mode.
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From SARS to MERS: crystallographic studies on coronaviral proteases enable antiviral drug designThree-dimensional domain swapping as a mechanism to lock the active conformation in a super-active octamer of SARS-CoV main proteaseDiscovery, synthesis, and structure-based optimization of a series of N-(tert-butyl)-2-(N-arylamido)-2-(pyridin-3-yl) acetamides (ML188) as potent noncovalent small molecule inhibitors of the severe acute respiratory syndrome coronavirus (SARS-CoV)Mechanism for controlling the monomer-dimer conversion of SARS coronavirus main proteaseDynamically-driven inactivation of the catalytic machinery of the SARS 3C-like protease by the N214A mutation on the extra domainIdentification of novel drug scaffolds for inhibition of SARS-CoV 3-Chymotrypsin-like protease using virtual and high-throughput screeningsLigand-induced Dimerization of Middle East Respiratory Syndrome (MERS) Coronavirus nsp5 Protease (3CLpro): IMPLICATIONS FOR nsp5 REGULATION AND THE DEVELOPMENT OF ANTIVIRALS.Purification, crystallization and preliminary X-ray analysis of nonstructural protein 2 (nsp2) from avian infectious bronchitis virus.Chimeric exchange of coronavirus nsp5 proteases (3CLpro) identifies common and divergent regulatory determinants of protease activitySARS-CoV 3CL protease cleaves its C-terminal autoprocessing site by novel subsite cooperativity.Activation and maturation of SARS-CoV main protease.Structure-based antivirals for emerging and neglected RNA viruses: an emerging field for medicinal chemistry in academia.Autoprocessing mechanism of severe acute respiratory syndrome coronavirus 3C-like protease (SARS-CoV 3CLpro) from its polyproteins.
P2860
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P2860
Liberation of SARS-CoV main protease from the viral polyprotein: N-terminal autocleavage does not depend on the mature dimerization mode.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Liberation of SARS-CoV main pr ...... the mature dimerization mode.
@en
type
label
Liberation of SARS-CoV main pr ...... the mature dimerization mode.
@en
prefLabel
Liberation of SARS-CoV main pr ...... the mature dimerization mode.
@en
P2093
P2860
P921
P1433
P1476
Liberation of SARS-CoV main pr ...... the mature dimerization mode.
@en
P2093
P2860
P2888
P356
10.1007/S13238-010-0011-4
P577
2010-01-01T00:00:00Z