HCV-infected hepatocytes drive CD4+ CD25+ Foxp3+ regulatory T-cell development through the Tim-3/Gal-9 pathway. - Wikidata - wikimedia - TriplyDB

HCV-infected hepatocytes drive CD4+ CD25+ Foxp3+ regulatory T-cell development through the Tim-3/Gal-9 pathway.

HCV-infected hepatocytes drive CD4+ CD25+ Foxp3+ regulatory T-cell development through the Tim-3/Gal-9 pathway.

http://www.wikidata.org/entity/Q41894013

about

Role of Tim-3 in hepatitis B virus infection: An overview Inflammatory status in human hepatic cirrhosis Increased numbers of CD5+CD19+CD1dhighIL-10+ Bregs, CD4+Foxp3+ Tregs, CD4+CXCR5+Foxp3+ follicular regulatory T (TFR) cells in CHB or CHC patients.Control of the inflammatory response mechanisms mediated by natural and induced regulatory T-cells in HCV-, HTLV-1-, and EBV-associated cancers.Cis association of galectin-9 with Tim-3 differentially regulates IL-12/IL-23 expressions in monocytes via TLR signaling Recipient T cell TIM-3 and hepatocyte galectin-9 signalling protects mouse liver transplants against ischemia-reperfusion injury.New Mechanism of Hepatic Fibrogenesis: Hepatitis C Virus Infection Induces Transforming Growth Factor β1 Production through Glucose-Regulated Protein 94.Differential regulation of interleukin-12 (IL-12)/IL-23 by Tim-3 drives T(H)17 cell development during hepatitis C virus infection.Presentation of hepatocellular antigens.Tim-3: an activation marker and activation limiter of innate immune cells CD4+ primary T cells expressing HCV-core protein upregulate Foxp3 and IL-10, suppressing CD4 and CD8 T cells.Hierarchical and selective roles of galectins in hepatocarcinogenesis, liver fibrosis and inflammation of hepatocellular carcinoma.Inhibitory receptor molecules in chronic hepatitis B and C infections: novel targets for immunotherapy?Re-wiring regulatory cell networks in immunity by galectin-glycan interactions.The role of exosomes in hepatitis, liver cirrhosis and hepatocellular carcinoma.MicroRNA-155 regulates interferon-γ production in natural killer cells via Tim-3 signalling in chronic hepatitis C virus infection.Galectin-9: From cell biology to complex disease dynamics.Hepatocyte-derived exosomes promote T follicular regulatory cell expansion during HCV infection.Protection of CD4+ T cells from hepatitis C virus infection-associated senescence via ΔNp63-miR-181a-Sirt1 pathway.Hepatitis C virus-induced myeloid-derived suppressor cells regulate T-cell differentiation and function via the signal transducer and activator of transcription 3 pathway.HCV-induced miR146a controls SOCS1/STAT3 and cytokine expression in monocytes to promote regulatory T-cell development.Tim-3 alters the balance of IL-12/IL-23 and drives TH17 cells: role in hepatitis B vaccine failure during hepatitis C infection.Translational Implication of Galectin-9 in the Pathogenesis and Treatment of Viral Infection.Induction, control, and plasticity of Treg cells: the immune regulatory network revised?HCV immune evasion and regulatory T cell activation: cause or consequence?

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P2860

HCV-infected hepatocytes drive CD4+ CD25+ Foxp3+ regulatory T-cell development through the Tim-3/Gal-9 pathway.

http://www.wikidata.org/entity/Q41894013

description

2012 nî lūn-bûn

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

@zh-tw

2012年论文

@wuu

2012年论文

@zh

2012年论文

@zh-cn

name

HCV-infected hepatocytes drive ...... rough the Tim-3/Gal-9 pathway.

@en

type

label

HCV-infected hepatocytes drive ...... rough the Tim-3/Gal-9 pathway.

@en

prefLabel

HCV-infected hepatocytes drive ...... rough the Tim-3/Gal-9 pathway.

@en

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P1433

European Journal of Immunology

P1476

HCV-infected hepatocytes drive ...... rough the Tim-3/Gal-9 pathway.

@en

P2093

Cheng J Ma

http://www.w3.org/2001/XMLSchema#string

Jia M Wang

http://www.w3.org/2001/XMLSchema#string

Jonathan P Moorman

http://www.w3.org/2001/XMLSchema#string

Mitsumi Hirashima

http://www.w3.org/2001/XMLSchema#string

Toshiro Niki

http://www.w3.org/2001/XMLSchema#string

Xiao J Ji

http://www.w3.org/2001/XMLSchema#string

Xiao Y Wu

http://www.w3.org/2001/XMLSchema#string

Zhi Q Yao

http://www.w3.org/2001/XMLSchema#string

P2860

A crucial role for Kupffer cell-derived galectin-9 in regulation of T cell immunity in hepatitis C infection

Galectin-9/TIM-3 interaction regulates virus-specific primary and memory CD8 T cell response

Control of regulatory T cell development by the transcription factor Foxp3

Global epidemiology of hepatitis C virus infection

Mechanisms of foxp3+ T regulatory cell-mediated suppression

Tim-3 negatively regulates IL-12 expression by monocytes in HCV infection.

HCV+ hepatocytes induce human regulatory CD4+ T cells through the production of TGF-beta

Regulatory ripples

Interleukin 10 acts on regulatory T cells to maintain expression of the transcription factor Foxp3 and suppressive function in mice with colitis

Tim-3 expression on PD-1+ HCV-specific human CTLs is associated with viral persistence, and its blockade restores hepatocyte-directed in vitro cytotoxicity

P304

458-467

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scholarly article

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10.1002/EJI.201242768

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2

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43

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2012-12-23T00:00:00Z

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23161469

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3757554

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