Fibrin deposited in the Alzheimer's disease brain promotes neuronal degeneration
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Breaking boundaries-coagulation and fibrinolysis at the neurovascular interfaceA Bacterial Component to Alzheimer’s-Type Dementia Seen via a Systems Biology Approach that Links Iron Dysregulation and Inflammagen Shedding to DiseaseEpidermal growth factor prevents APOE4-induced cognitive and cerebrovascular deficits in female mice.Viscoelastic and ultrastructural characteristics of whole blood and plasma in Alzheimer-type dementia, and the possible role of bacterial lipopolysaccharides (LPS)The neuropathology and cerebrovascular mechanisms of dementiaNeurovascular dysfunction and neurodegeneration in dementia and Alzheimer's diseaseThe Alzheimer's disease peptide β-amyloid promotes thrombin generation through activation of coagulation factor XII.A semi-mechanism approach based on MRI and proteomics for prediction of conversion from mild cognitive impairment to Alzheimer's diseaseHyperhomocysteinemia exacerbates Alzheimer's disease pathology by way of the β-amyloid fibrinogen interactionAngry macrophages patrol for fibrin.Interactions of β-amyloid peptide with fibrinogen and coagulation factor XII may contribute to Alzheimer's diseaseFamily History of Alzheimer's Disease and Cortical Thickness in Patients With Dementia.Biochemical and structural analysis of the interaction between β-amyloid and fibrinogen.Plasma fibrinogen is a natural deterrent to amyloid beta-induced platelet activation and neuronal toxicity.In Vivo Imaging of CNS Injury and Disease.Fibrinogen-Derived γ377-395 Peptide Improves Cognitive Performance and Reduces Amyloid-β Deposition, without Altering Inflammation, in AβPP/PS1 Mice.Alzheimer disease is in part a thrombohemorrhagic disorder.Pericyte degeneration causes white matter dysfunction in the mouse central nervous system.Depletion of coagulation factor XII ameliorates brain pathology and cognitive impairment in Alzheimer disease mice.Differing associations between Aβ accumulation, hypoperfusion, blood-brain barrier dysfunction and loss of PDGFRB pericyte marker in the precuneus and parietal white matter in Alzheimer's disease.The evolution of fibrin-specific targeting strategies.Aminopyrimidine Class Aggregation Inhibitor Effectively Blocks Aβ-Fibrinogen Interaction and Aβ-Induced Contact System Activation.Blood will out: vascular contributions to Alzheimer's disease.Spatiotemporal distribution of fibrinogen in marmoset and human inflammatory demyelination.Analysis of Progression Toward Alzheimer's Disease Based on Evolutionary Weighted Random Support Vector Machine Cluster
P2860
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P2860
Fibrin deposited in the Alzheimer's disease brain promotes neuronal degeneration
description
2014 nî lūn-bûn
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2014年の論文
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2014年論文
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2014年論文
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2014年論文
@zh-hk
2014年論文
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2014年論文
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2014年论文
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2014年论文
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2014年论文
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name
Fibrin deposited in the Alzheimer's disease brain promotes neuronal degeneration
@en
type
label
Fibrin deposited in the Alzheimer's disease brain promotes neuronal degeneration
@en
prefLabel
Fibrin deposited in the Alzheimer's disease brain promotes neuronal degeneration
@en
P2093
P2860
P1476
Fibrin deposited in the Alzheimer's disease brain promotes neuronal degeneration
@en
P2093
Allison T Richards
Larissa Mattei
Marta Cortes-Canteli
P2860
P304
P356
10.1016/J.NEUROBIOLAGING.2014.10.030
P577
2014-10-31T00:00:00Z