Gli protein activity is controlled by multisite phosphorylation in vertebrate Hedgehog signaling. - Wikidata - wikimedia - TriplyDB

Gli protein activity is controlled by multisite phosphorylation in vertebrate Hedgehog signaling.

Gli protein activity is controlled by multisite phosphorylation in vertebrate Hedgehog signaling.

http://www.wikidata.org/entity/Q41917900

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Deciphering the role of hedgehog signaling in pancreatic cancer Hedgehog signaling: modulation of cancer properies and tumor mircroenvironment Non-Canonical Hh Signaling in Cancer-Current Understanding and Future Directions Hedgehog Signaling in the Maintenance of Cancer Stem Cells Cooperative integration between HEDGEHOG-GLI signalling and other oncogenic pathways: implications for cancer therapy Primary cilium and sonic hedgehog signaling during neural tube patterning: role of GPCRs and second messengers Context-dependent signal integration by the GLI code: the oncogenic load, pathways, modifiers and implications for cancer therapy A mutation in the mouse ttc26 gene leads to impaired hedgehog signaling Set7 mediated Gli3 methylation plays a positive role in the activation of Sonic Hedgehog pathway in mammals Smoothened Regulation: A Tale of Two Signals.Regulation of Sufu activity by p66β and Mycbp provides new insight into vertebrate Hedgehog signaling.Kinetic analysis of BCL11B multisite phosphorylation-dephosphorylation and coupled sumoylation in primary thymocytes by multiple reaction monitoring mass spectroscopy.Hedgehog-induced phosphorylation by CK1 sustains the activity of Ci/Gli activator Impact of phosphomimetic and non-phosphorylatable mutations of phospholemman on L-type calcium channels gating in HEK 293T cells.An in vivo chemical genetic screen identifies phosphodiesterase 4 as a pharmacological target for hedgehog signaling inhibition Inactivation of a Gα(s)-PKA tumour suppressor pathway in skin stem cells initiates basal-cell carcinogenesis.Intraflagellar transport 27 is essential for hedgehog signaling but dispensable for ciliogenesis during hair follicle morphogenesis.A conserved role for Notch signaling in priming the cellular response to Shh through ciliary localisation of the key Shh transducer Smo.AMP-Activated Protein Kinase Directly Phosphorylates and Destabilizes Hedgehog Pathway Transcription Factor GLI1 in Medulloblastoma.Ciliary Entry of the Hedgehog Transcriptional Activator Gli2 Is Mediated by the Nuclear Import Machinery but Differs from Nuclear Transport in Being Imp-α/β1-Independent Deubiquitination of Ci/Gli by Usp7/HAUSP Regulates Hedgehog Signaling.Measuring Gli2 Phosphorylation by Selected Reaction Monitoring Mass Spectrometry.Cholesterol activates the G-protein coupled receptor Smoothened to promote Hedgehog signaling.G-protein-coupled receptors, Hedgehog signaling and primary cilia.Developmental signaling: does it bridge the gap between cilia dysfunction and renal cystogenesis?Canonical and non-canonical Hedgehog signalling and the control of metabolism.Transcriptional regulation of graded Hedgehog signaling Motor neurons and the generation of spinal motor neuron diversity Nestin Mediates Hedgehog Pathway Tumorigenesis.Regulation of the oncoprotein Smoothened by small molecules.Cell Cycle-Related Kinase (CCRK) regulates ciliogenesis and Hedgehog signaling in mice.Hedgehog signaling pathway: a novel model and molecular mechanisms of signal transduction.The Orphan G Protein-coupled Receptor Gpr175 (Tpra40) Enhances Hedgehog Signaling by Modulating cAMP Levels Cilia-dependent GLI processing in neural crest cells is required for tongue development.Hedgehog Signal Transduction: Key Players, Oncogenic Drivers, and Cancer Therapy.Pyrvinium attenuates Hedgehog signaling downstream of smoothened.Primary Cilia and Mammalian Hedgehog Signaling.Primary Cilia in Cystic Kidney Disease.Regulation of Gli ciliary localization and Hedgehog signaling by the PY-NLS/karyopherin-β2 nuclear import system.Bimodal antagonism of PKA signalling by ARHGAP36.

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P2860

Gli protein activity is controlled by multisite phosphorylation in vertebrate Hedgehog signaling.

http://www.wikidata.org/entity/Q41917900

description

2013 nî lūn-bûn

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2013年の論文

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2013年論文

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2013年論文

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2013年论文

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2013年论文

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2013年论文

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name

Gli protein activity is contro ...... vertebrate Hedgehog signaling.

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type

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Gli protein activity is contro ...... vertebrate Hedgehog signaling.

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Gli protein activity is contro ...... vertebrate Hedgehog signaling.

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J.CELREP.2013.12.003

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P1476

Gli protein activity is contro ...... vertebrate Hedgehog signaling

@en

P2093

Bennett G Novitch

http://www.w3.org/2001/XMLSchema#string

Eric W Humke

http://www.w3.org/2001/XMLSchema#string

Jennifer H Kong

http://www.w3.org/2001/XMLSchema#string

Rajat Rohatgi

http://www.w3.org/2001/XMLSchema#string

Robert Ahrends

http://www.w3.org/2001/XMLSchema#string

Sohini Khan

http://www.w3.org/2001/XMLSchema#string

Yan Ma

http://www.w3.org/2001/XMLSchema#string

P2860

Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb

Evidence for the direct involvement of {beta}TrCP in Gli3 protein processing

A binding site for Gli proteins is essential for HNF-3beta floor plate enhancer activity in transgenics and can respond to Shh in vitro

Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome

A gradient of Gli activity mediates graded Sonic Hedgehog signaling in the neural tube

The output of Hedgehog signaling is controlled by the dynamic association between Suppressor of Fused and the Gli proteins

Absolute quantification of proteins and phosphoproteins from cell lysates by tandem MS

High-throughput generation of tagged stable cell lines for proteomic analysis.

Vertebrate Smoothened functions at the primary cilium.

Concerted dephosphorylation of the transcription factor NFAT1 induces a conformational switch that regulates transcriptional activity

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168-181

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scholarly article

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10.1016/J.CELREP.2013.12.003

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1

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6

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Pawel Niewiadomski

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2013-12-27T00:00:00Z

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259490151

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24373970

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P921

phosphorylation

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3915062

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