The homologous recombination machinery modulates the formation of RNA-DNA hybrids and associated chromosome instability.
about
Out of balance: R-loops in human diseaseReplication-Associated Recombinational Repair: Lessons from Budding YeastDNA repair by RNA: Templated, or not templated, that is the questionDNA repair targeted therapy: The past or future of cancer treatment?Breaking bad: R-loops and genome integrityMechanisms and regulation of mitotic recombination in Saccharomyces cerevisiaeSources of DNA double-strand breaks and models of recombinational DNA repairCrystal structure of RNase H3–substrate complex reveals parallel evolution of RNA/DNA hybrid recognitionChoices have consequences: the nexus between DNA repair pathways and genomic instability in cancerThe deletion of rnhB in Mycobacterium smegmatis does not affect the level of RNase HII substrates or influence genome stabilityMechanisms and Consequences of Double-Strand DNA Break Formation in ChromatinS1-DRIP-seq identifies high expression and polyA tracts as major contributors to R-loop formation.Mechanisms of genome instability induced by RNA-processing defects.A double-edged sword: R loops as threats to genome integrity and powerful regulators of gene expressionPathways and Mechanisms that Prevent Genome Instability in Saccharomyces cerevisiaeROCC, a conserved region in cohesin's Mcd1 subunit, is essential for the proper regulation of the maintenance of cohesion and establishment of condensation.Genome-wide profiling of yeast DNA:RNA hybrid prone sites with DRIP-chipRNase H enables efficient repair of R-loop induced DNA damage.Rescue from replication stress during mitosis.Dicer promotes transcription termination at sites of replication stress to maintain genome stabilityHuman papillomavirus type 16 E7 oncoprotein causes a delay in repair of DNA damageA novel mechanism for the establishment of sister chromatid cohesion by the ECO1 acetyltransferase.RNA polymerase III regulates cytosolic RNA:DNA hybrids and intracellular microRNA expression.RNA-processing proteins regulate Mec1/ATR activation by promoting generation of RPA-coated ssDNARECQL5 has unique strand annealing properties relative to the other human RecQ helicase proteins.The Yin and Yang of R-loop biology.Regulated Formation of lncRNA-DNA Hybrids Enables Faster Transcriptional Induction and Environmental Adaptation.A Checkpoint-Related Function of the MCM Replicative Helicase Is Required to Avert Accumulation of RNA:DNA Hybrids during S-phase and Ensuing DSBs during G2/MEmerging role of RNA•DNA hybrids in C9orf72-linked neurodegeneration.Interallelic complementation provides functional evidence for cohesin-cohesin interactions on DNA.Preferential expression of scores of functionally and evolutionarily diverse DNA and RNA-binding proteins during Oxytricha trifallax macronuclear development.RNA:DNA hybrids in the human genome have distinctive nucleotide characteristics, chromatin composition, and transcriptional relationships.R loops regulate promoter-proximal chromatin architecture and cellular differentiation.The ATPases of cohesin interface with regulators to modulate cohesin-mediated DNA tethering.The spliceosome-associated protein Nrl1 suppresses homologous recombination-dependent R-loop formation in fission yeast.Transcript RNA supports precise repair of its own DNA gene.DNA repair pathway gene expression score correlates with repair proficiency and tumor sensitivity to chemotherapy.Transcript-RNA-templated DNA recombination and repairPutative RNA-Directed Adaptive Mutations in Cancer Evolution.Differential roles of the RNases H in preventing chromosome instability.
P2860
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P2860
The homologous recombination machinery modulates the formation of RNA-DNA hybrids and associated chromosome instability.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
The homologous recombination m ...... ciated chromosome instability.
@en
type
label
The homologous recombination m ...... ciated chromosome instability.
@en
prefLabel
The homologous recombination m ...... ciated chromosome instability.
@en
P2860
P356
P1433
P1476
The homologous recombination m ...... ociated chromosome instability
@en
P2093
Douglas Koshland
Steven K Gore
P2860
P304
P356
10.7554/ELIFE.00505
P407
P50
P577
2013-06-11T00:00:00Z