Rational design of new binding specificity by simultaneous mutagenesis of calmodulin and a target peptide
about
Rational approaches to improving selectivity in drug designIs there a path beyond BOLD? Molecular imaging of brain functionStructure-based Protocol for Identifying Mutations that Enhance Protein–Protein Binding AffinitiesStructural, kinetic, and thermodynamic studies of specificity designed HIV-1 proteaseComputationally mapping sequence space to understand evolutionary protein engineering.Designing specific protein-protein interactions using computation, experimental library screening, or integrated methodsElucidating the mechanisms of cooperative calcium-calmodulin interactions: a structural systems biology approach.Bioengineered probes for molecular magnetic resonance imaging in the nervous system.Specificity in molecular design: a physical framework for probing the determinants of binding specificity and promiscuity in a biological environment.Progress in computational protein design.Carbohydrate recognition by the antiviral lectin cyanovirin-N.Optimal drug cocktail design: methods for targeting molecular ensembles and insights from theoretical model systems.X-ray vs. NMR structures as templates for computational protein design.Challenges in the computational design of proteinsThe MOD-QM/MM Method: Applications to Studies of Photosystem II and DNA G-Quadruplexes.Rational and computational design of stabilized variants of cyanovirin-N that retain affinity and specificity for glycan ligands.Modeling backbone flexibility to achieve sequence diversity: the design of novel alpha-helical ligands for Bcl-xL.Fast gap-free enumeration of conformations and sequences for protein design.Identification of novel inhibitors of the translationally controlled tumor protein (TCTP): insights from molecular dynamics.An engineered calmodulin-based allosteric switch for Peptide biosensing.Computational protein design with a generalized Born solvent model: application to Asparaginyl-tRNA synthetase.
P2860
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P2860
Rational design of new binding specificity by simultaneous mutagenesis of calmodulin and a target peptide
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Rational design of new binding ...... almodulin and a target peptide
@en
type
label
Rational design of new binding ...... almodulin and a target peptide
@en
prefLabel
Rational design of new binding ...... almodulin and a target peptide
@en
P2093
P2860
P356
P1433
P1476
Rational design of new binding ...... almodulin and a target peptide
@en
P2093
Alan Jasanoff
Andrew T Dennis
Bruce Tidor
David F Green
Peter S Fam
P2860
P304
12547-12559
P356
10.1021/BI060857U
P407
P577
2006-10-01T00:00:00Z