Bone morphogenetic protein receptor type II C-terminus interacts with c-Src: implication for a role in pulmonary arterial hypertension.
about
BMP2 and mechanical loading cooperatively regulate immediate early signalling events in the BMP pathwayMicrovessel mechanobiology in pulmonary arterial hypertension: cause and effectBMP-7 enhances cell migration and αvβ3 integrin expression via a c-Src-dependent pathway in human chondrosarcoma cellsCadherin-6B is required for the generation of Islet-1-expressing dorsal interneurons.Cadherin-6B stimulates an epithelial mesenchymal transition and the delamination of cells from the neural ectoderm via LIMK/cofilin mediated non-canonical BMP receptor signaling.Endoglin-mediated suppression of prostate cancer invasion is regulated by activin and bone morphogenetic protein type II receptors.Interaction between src family kinases and rho-kinase in agonist-induced Ca2+-sensitization of rat pulmonary artery.Role for miR-204 in human pulmonary arterial hypertensionHeterozygous null bone morphogenetic protein receptor type 2 mutations promote SRC kinase-dependent caveolar trafficking defects and endothelial dysfunction in pulmonary arterial hypertension.Physiologic and molecular consequences of endothelial Bmpr2 mutation.BMP2-induced chemotaxis requires PI3K p55γ/p110α-dependent phosphatidylinositol (3,4,5)-triphosphate production and LL5β recruitment at the cytocortexThe genetics of pulmonary arterial hypertension in the post-BMPR2 era.Cytoskeletal defects in Bmpr2-associated pulmonary arterial hypertensionSerotonin 2B Receptor Antagonism Prevents Heritable Pulmonary Arterial Hypertension.Inhibition of BMP and of TGFβ receptors downregulates expression of XIAP and TAK1 leading to lung cancer cell death.Metabolomic analysis of bone morphogenetic protein receptor type 2 mutations in human pulmonary endothelium reveals widespread metabolic reprogramming.Connectivity map analysis of nonsense-mediated decay-positive BMPR2-related hereditary pulmonary arterial hypertension provides insights into disease penetrance.Pathogenic mechanisms of pulmonary arterial hypertension.Raf/ERK drives the proliferative and invasive phenotype of BMPR2-silenced pulmonary artery endothelial cells.VE-cadherin facilitates BMP-induced endothelial cell permeability and signalingMice expressing BMPR2R899X transgene in smooth muscle develop pulmonary vascular lesions.Genetics and genomics of pulmonary arterial hypertension.A potential role for insulin resistance in experimental pulmonary hypertensionGender, sex hormones and pulmonary hypertension.Anti-inflammatory and antiatherogenic role of BMP receptor II in endothelial cells.Rho-kinase inhibition alleviates pulmonary hypertension in transgenic mice expressing a dominant-negative type II bone morphogenetic protein receptor gene.TNFα drives pulmonary arterial hypertension by suppressing the BMP type-II receptor and altering NOTCH signalling.From oncoproteins/tumor suppressors to microRNAs, the newest therapeutic targets for pulmonary arterial hypertension.Bone Morphogenetic Protein functions as a context-dependent angiogenic cue in vertebrates.Epigenetics: novel mechanism of pulmonary hypertension.BMP growth factor signaling in a biomechanical context.Vascular remodeling process in pulmonary arterial hypertension, with focus on miR-204 and miR-126 (2013 Grover Conference series).Control of vascular smooth muscle function by Src-family kinases and reactive oxygen species in health and disease.BMP2 rescues deficient cell migration in Tgfbr3(-/-) epicardial cells and requires Src kinase.Signaling Receptors for TGF-β Family Members.Anti-inflammatory and anti-atherogenic role of BMP receptor II in atherosclerosis.Genetic and pharmacological inhibition of retinoic acid receptor γ function promotes endochondral bone formation.BMP-dependent activation of caspase-9 and caspase-8 mediates apoptosis in pulmonary artery smooth muscle cells.Neprilysin regulates pulmonary artery smooth muscle cell phenotype through a platelet-derived growth factor receptor-dependent mechanism.IRS4, a novel modulator of BMP/Smad and Akt signalling during early muscle differentiation.
P2860
Q24317657-65B401E3-75AF-4800-897F-50E41D3659F2Q27009717-483418EC-C6FB-479F-9AEB-E781786F05C8Q28544902-EC781270-8FC8-41A6-A17C-D0512B8EA63CQ30300416-2148D079-D6BF-4E99-AC53-E6FC05B2A611Q30418766-6CD31CD0-1404-462B-81BA-6D559F7A5F14Q31126839-4DD62E85-8531-4725-9E03-59BBAB0E35A1Q33703906-19DAEE62-98F9-431A-BB3C-E176C4FEACF6Q34681312-DE59A6CF-64F6-4ACB-86A8-5D004D57BEFDQ34958933-4801E2FF-8C80-4B8E-A397-03D4BE685E3EQ35121379-F77F55CC-CB21-4BB3-8A3A-EF65FA1416ADQ35178694-D91FB567-47E2-47D6-AF4B-DABED427D25AQ35573919-3B42C3A7-C81B-4FA2-9108-05AE4DF52BF1Q35850232-92AD6829-ACBB-404A-BAC2-F40E2DD18057Q35919662-5B6DDAAA-EE34-4590-A61E-D0E9ABAAB907Q35980393-199BFF16-9B72-42E9-9647-048159BB241CQ36108056-BED89F6F-08ED-4A58-B214-4B0A34E71185Q36110556-EE750A63-EECA-4629-A065-E74144056BB5Q36447388-9E0F66B1-DC49-4719-A966-992CBDAE695BQ36480359-86982E81-CA24-4290-AA83-D6D33ECC64E8Q36518633-FB7B972C-7E40-4A44-BF17-F875F30890DBQ36977330-4B74AE4D-30F6-4778-B46B-B203E2B7558FQ37051037-1BB7C075-1721-46BA-91C6-59AF87C30285Q37104263-2F700E5F-1315-49C4-BAC1-9C6B60107D6BQ37133789-6F25AFE8-9BF4-4E2D-9FAB-E310C1AF0851Q37136717-3AA6F7BE-FAA3-471C-AA82-F755BC1BEBFDQ37174962-2053978C-2A96-480B-86C4-D52FB61CE1E7Q37591432-F178D1B5-37EB-4A87-B242-EF78B3FD9A4EQ37901411-DB03ABD0-9AD2-4F83-A361-08906C52F547Q37947050-0ACB0CEB-40C5-4533-A094-53DB8C67E19FQ38139834-FDF72AA5-890A-459E-9E6B-B6BC350CEFF0Q38152403-2C9EF55F-CBA6-42D5-A483-34A133B27E1FQ38227557-ACB22A86-374F-432E-AF13-F4FFF0D194CAQ38266683-21F0C551-9A6A-4F5F-8E57-154638E70B34Q38813760-C5B7B79E-E518-44DE-A7F0-E5CEB4F0369CQ38915720-231EAE39-FBEF-4233-B773-B297AD7F0597Q39352897-4DBFE678-700D-46F2-BA3E-35772E39D2B5Q39668321-092065FF-9C1F-4AE6-BBFB-C22A8DECF603Q40221971-FC244148-582A-4CAF-9EF9-9790E90CCB1FQ41201643-9CCD1BD5-795D-4FE1-8CA5-C04B78FC8C35Q41458783-C14A3C1B-41A4-4EF0-AF7D-22CC1522B70C
P2860
Bone morphogenetic protein receptor type II C-terminus interacts with c-Src: implication for a role in pulmonary arterial hypertension.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Bone morphogenetic protein rec ...... lmonary arterial hypertension.
@en
type
label
Bone morphogenetic protein rec ...... lmonary arterial hypertension.
@en
prefLabel
Bone morphogenetic protein rec ...... lmonary arterial hypertension.
@en
P2093
P2860
P356
P1476
Bone morphogenetic protein rec ...... lmonary arterial hypertension.
@en
P2093
James A Knowles
Jane H Morse
Wai K P Wong
P2860
P304
P356
10.1165/RCMB.2005-0103OC
P577
2005-07-07T00:00:00Z