Substrate structure-activity relationships guide rational engineering of modular polyketide synthase ketoreductases. - Wikidata - wikimedia - TriplyDB

Substrate structure-activity relationships guide rational engineering of modular polyketide synthase ketoreductases.

Substrate structure-activity relationships guide rational engineering of modular polyketide synthase ketoreductases.

http://www.wikidata.org/entity/Q41968771

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Epimerase and Reductase Activities of Polyketide Synthase Ketoreductase Domains Utilize the Same Conserved Tyrosine and Serine Residues.Methyltransferases excised from trans-AT polyketide synthases operate on N-acetylcysteamine-bound substrates.Stereocontrol within polyketide assembly lines.Towards Precision Engineering of Canonical Polyketide Synthase Domains: Recent Advances and Future Prospects.Polyene macrolide biosynthesis in streptomycetes and related bacteria: recent advances from genome sequencing and experimental studies.Engineering modular polyketide synthases for production of biofuels and industrial chemicals.Mechanism and Stereochemistry of Polyketide Chain Elongation and Methyl Group Epimerization in Polyether Biosynthesis.Engineered polyketides: Synergy between protein and host level engineering.Dissecting how modular polyketide synthase ketoreductases interact with acyl carrier protein-attached substrates.Molecular Genetic Characterization of an Anthrabenzoxocinones Gene Cluster in Streptomyces Sp. FJS31-2 for the Biosynthesis of BE-24566B and Zunyimycin Ale.Substrate-bound structures of a ketoreductase from amphotericin modular polyketide synthase.Structural and Functional Trends in Dehydrating Bimodules from trans-Acyltransferase Polyketide Synthases.

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Substrate structure-activity relationships guide rational engineering of modular polyketide synthase ketoreductases.

http://www.wikidata.org/entity/Q41968771

description

2015 nî lūn-bûn

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

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name

Substrate structure-activity r ...... etide synthase ketoreductases.

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Substrate structure-activity r ...... etide synthase ketoreductases.

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Substrate structure-activity r ...... etide synthase ketoreductases.

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Chemical Communications

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Substrate structure-activity r ...... etide synthase ketoreductases.

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Adrian T Keatinge-Clay

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Marjolein E Pasman

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P2860

A tylosin ketoreductase reveals how chirality is determined in polyketides

Structural and functional analysis of A-type ketoreductases from the amphotericin modular polyketide synthase

Structural and Stereochemical Analysis of a Modular Polyketide Synthase Ketoreductase Domain Required for the Generation of a cis-Alkene

Structural and functional studies of atrans-acyltransferase polyketide assembly line enzyme that catalyzes stereoselective α- and β-ketoreduction

Crystal structure of (R)-3-hydroxybutyryl-CoA dehydrogenase PhaB from Ralstonia eutropha

Ketoreduction in mycolactone biosynthesis: insight into substrate specificity and stereocontrol from studies of discrete ketoreductase domains in vitro

Modern aldol methods for the total synthesis of polyketides.

The biosynthetic logic of polyketide diversity.

The structures of type I polyketide synthases.

A model of structure and catalysis for ketoreductase domains in modular polyketide synthases.

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792-795

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scholarly article

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10.1039/C5CC07315D

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4

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Constance B Bailey

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2015-11-16T00:00:00Z

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26568113

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4690787

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