Metformin prevents and reverses inflammation in a non-diabetic mouse model of nonalcoholic steatohepatitis.
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Extracellular matrix and liver diseaseMetformin and metabolic diseases: a focus on hepatic aspectsThe 5'-AMP-Activated Protein Kinase (AMPK) Is Involved in the Augmentation of Antioxidant Defenses in Cryopreserved Chicken SpermInterspecies NASH disease activity whole-genome profiling identifies a fibrogenic role of PPARα-regulated dermatopontinPossible role of interleukin-1β in type 2 diabetes onset and implications for anti-inflammatory therapy strategies.Inhibiting monoacylglycerol acyltransferase 1 ameliorates hepatic metabolic abnormalities but not inflammation and injury in miceColorectal and Prostate Cancer Risk in Diabetes: Metformin, an Actor behind the Scene.Continuation of metformin use after a diagnosis of cirrhosis significantly improves survival of patients with diabetes.Liver kinase B1 suppresses lipopolysaccharide-induced nuclear factor κB (NF-κB) activation in macrophagesMetformin ameliorates hepatic steatosis and inflammation without altering adipose phenotype in diet-induced obesity.Overexpression of Peroxiredoxin 4 Affects Intestinal Function in a Dietary Mouse Model of Nonalcoholic Fatty Liver Disease.Metformin prevents hepatocellular carcinoma development by suppressing hepatic progenitor cell activation in a rat model of cirrhosis.Pharmacometabolomic Assessment of Metformin in Non-diabetic, African Americans.Metformin Reduces Bleomycin-induced Pulmonary Fibrosis in Mice.The effects of prenatal metformin on obesogenic diet-induced alterations in maternal and fetal fatty acid metabolismNonalcoholic Fatty liver: a possible new target for type 2 diabetes prevention and treatment.Peroxiredoxin 4 protects against nonalcoholic steatohepatitis and type 2 diabetes in a nongenetic mouse model.Palmitate-induced activation of mitochondrial metabolism promotes oxidative stress and apoptosis in H4IIEC3 rat hepatocytesMetformin in the treatment of non-alcoholic fatty liver disease: safety, efficacy and mechanism.Insulin sensitizers for the treatment of non-alcoholic fatty liver diseaseRole of MicroRNAs in NAFLD/NASH.Metformin: A Hopeful Promise in Aging Research.Metformin Prevents Renal Fibrosis in Mice with Unilateral Ureteral Obstruction and Inhibits Ang II-Induced ECM Production in Renal Fibroblasts.Metformin protects primary rat hepatocytes against oxidative stress-induced apoptosis.MicroRNA profiles following metformin treatment in a mouse model of non-alcoholic steatohepatitis.Heparin modulation on hepatic nitric oxide synthase in experimental steatohepatitisMetformin prevents peritendinous fibrosis by inhibiting transforming growth factor-β signaling.Peroxiredoxin 4 (PRDX4): Its critical in vivo roles in animal models of metabolic syndrome ranging from atherosclerosis to nonalcoholic fatty liver disease.Metformin reduces hepatic resistance and portal pressure in cirrhotic rats.Metformin attenuates renal fibrosis in both AMPKα2-dependent and independent manners.Compound K attenuates glucose intolerance and hepatic steatosis through AMPK-dependent pathways in type 2 diabetic OLETF rats.A Simple Diet- and Chemical-Induced Murine NASH Model with Rapid Progression of Steatohepatitis, Fibrosis and Liver Cancer.Protective Effect of Metformin against Acute Inflammation and Oxidative Stress in Rat.The Eeffect of Metformin Combined with Calcium-Vitamin D3 Against Diet-Induced Nonalcoholic Fatty Liver Disease.Short treatment of metformin attenuated insulin resistance and hepatic steatosis in obese mice by mechanisms independents of PPAR-alpha.Targeting a phospho-STAT3-miRNAs pathway improves vesicular hepatic steatosis in an in vitro and in vivo modelLiver enzyme trends in patients taking uninterrupted metformin before and after coronary surgery
P2860
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P2860
Metformin prevents and reverses inflammation in a non-diabetic mouse model of nonalcoholic steatohepatitis.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Metformin prevents and reverse ...... nonalcoholic steatohepatitis.
@en
type
label
Metformin prevents and reverse ...... nonalcoholic steatohepatitis.
@en
prefLabel
Metformin prevents and reverse ...... nonalcoholic steatohepatitis.
@en
P2093
P2860
P1433
P1476
Metformin prevents and reverse ...... nonalcoholic steatohepatitis.
@en
P2093
Akio Fujimura
Hirofumi Misu
Hitoshi Ando
Ken-Ichiro Kato
Ken-ichi Miyamoto
Koji Hayashi
Masafumi Uno
Naoto Matsuzawa-Nagata
Seiichiro Kurita
Shuichi Kaneko
P2860
P304
P356
10.1371/JOURNAL.PONE.0043056
P407
P577
2012-09-18T00:00:00Z