Repurposing Lesogaberan to Promote Human Islet Cell Survival and β-Cell Replication.

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Repurposing Lesogaberan to Promote Human Islet Cell Survival and β-Cell Replication.

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2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年學術文章

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2017年學術文章

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2017年學術文章

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Repurposing Lesogaberan to Promote Human Islet Cell Survival and β-Cell Replication.

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Repurposing Lesogaberan to Promote Human Islet Cell Survival and β-Cell Replication.

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Repurposing Lesogaberan to Promote Human Islet Cell Survival and β-Cell Replication.

@en

Repurposing Lesogaberan to Promote Human Islet Cell Survival and β-Cell Replication.

@nl

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Repurposing Lesogaberan to Promote Human Islet Cell Survival and β-Cell Replication.

@en

Repurposing Lesogaberan to Promote Human Islet Cell Survival and β-Cell Replication.

@nl

P1476

Repurposing Lesogaberan to Promote Human Islet Cell Survival and β-Cell Replication

@en

P2093

Angela Hu

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Hoa Dang

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Jide Tian

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Willem Xu

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P2860

Combining antigen-based therapy with GABA treatment synergistically prolongs survival of transplanted ß-cells in diabetic NOD mice

Artemisinins Target GABAA Receptor Signaling and Impair α Cell Identity

Regulated exocytosis of GABA-containing synaptic-like microvesicles in pancreatic beta-cells.

GABAB receptor activation inhibits exocytosis in rat pancreatic beta-cells by G-protein-dependent activation of calcineurin.

Evaluation of the pharmacokinetic interaction between lesogaberan (AZD3355) and esomeprazole in healthy subjects.

Clinically applicable GABA receptor positive allosteric modulators promote ß-cell replication

Gamma-aminobutyric acid (GABA) is an autocrine excitatory transmitter in human pancreatic beta-cells.

Combined therapy with GABA and proinsulin/alum acts synergistically to restore long-term normoglycemia by modulating T-cell autoimmunity and promoting β-cell replication in newly diabetic NOD mice.

Glucose-inhibition of glucagon secretion involves activation of GABAA-receptor chloride channels.

Synthesis and pharmacological evaluation of novel gamma-aminobutyric acid type B (GABAB) receptor agonists as gastroesophageal reflux inhibitors.

P304

6403539

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P31

scholarly article

P356

10.1155/2017/6403539

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P478

2017

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P50

Daniel L Kaufman

P577

2017-09-05T00:00:00Z

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P698

29018828

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P932

5605788

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