siRNA function in RNAi: a chemical modification analysis.
about
Translation repression in human cells by microRNA-induced gene silencing requires RCK/p54Small interfering RNAs containing full 2'-O-methylribonucleotide-modified sense strands display Argonaute2/eIF2C2-dependent activity.Light-dependent RNA interference with nucleobase-caged siRNAssiRNA target site secondary structure predictions using local stable substructuresCatalytic mechanism of Escherichia coli ribonuclease III: kinetic and inhibitor evidence for the involvement of two magnesium ions in RNA phosphodiester hydrolysisModulating HIV-1 replication by RNA interference directed against human transcription elongation factor SPT5The RNA silencing pathway: the bits and pieces that matterInsights into the kinetics of siRNA-mediated gene silencing from live-cell and live-animal bioluminescent imagingTherapeutic Oligonucleotides Targeting Liver Disease: TTR AmyloidosissiRNA Versus miRNA as Therapeutics for Gene SilencingSolution-state structure of a fully alternately 2'-F/2'-OMe modified 42-nt dimeric siRNA constructUnexpected origins of the enhanced pairing affinity of 2'-fluoro-modified RNAThe Crystal Structure of Human Argonaute2Structure of yeast Argonaute with guide RNARNA interference-based nanosystems for inflammatory bowel disease therapyKnocking down disease: a progress report on siRNA therapeuticsTechnologies for controlled, local delivery of siRNAStructural basis for overhang-specific small interfering RNA recognition by the PAZ domainRNA-based mechanisms regulating host-virus interactionsMolecular mechanisms of RNA interferenceMicroRNA control of PHABULOSA in leaf development: importance of pairing to the microRNA 5' regionBionanotechnology and the future of glioma.Sniffing for gene-silencing efficiency of siRNAs in HeLa cells in comparison with that in HEK293T cells: correlation between knockdown efficiency and sustainability of sirnas revealed by FRET-based probingShort interfering RNA (siRNA) as a novel therapeutic.Integrated siRNA design based on surveying of features associated with high RNAi effectiveness.Improving model predictions for RNA interference activities that use support vector machine regression by combining and filtering features.Chemical modification: the key to clinical application of RNA interference?The dynamics and efficacy of antiviral RNA silencing: A model study.Synthesis and gene silencing properties of siRNAs containing terminal amide linkages.Both strands of siRNA have potential to guide posttranscriptional gene silencing in mammalian cells.Gold nanoparticles for biology and medicine.Effects of chemical modification on the potency, serum stability, and immunostimulatory properties of short shRNAs.Advances in Systemic siRNA DeliveryCombinatorial approach to determine functional group effects on lipidoid-mediated siRNA delivery.High-density lipoproteins for the systemic delivery of short interfering RNA.Transfection of Antisense Oligonucleotides Mediated by Cationic Vesicles Based on Non-Ionic Surfactant and Polycations Bearing Quaternary Ammonium Moieties.Probing the inherent stability of siRNA immobilized on nanoparticle constructs.siRNA-like double-stranded RNAs are specifically protected against degradation in human cell extract.2'-OMe-phosphorodithioate-modified siRNAs show increased loading into the RISC complex and enhanced anti-tumour activity.Structural basis for 5'-end-specific recognition of guide RNA by the A. fulgidus Piwi protein.
P2860
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P2860
siRNA function in RNAi: a chemical modification analysis.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh
2003年學術文章
@zh-hant
name
siRNA function in RNAi: a chemical modification analysis.
@en
siRNA function in RNAi: a chemical modification analysis.
@nl
type
label
siRNA function in RNAi: a chemical modification analysis.
@en
siRNA function in RNAi: a chemical modification analysis.
@nl
prefLabel
siRNA function in RNAi: a chemical modification analysis.
@en
siRNA function in RNAi: a chemical modification analysis.
@nl
P2860
P356
P1433
P1476
siRNA function in RNAi: a chemical modification analysis.
@en
P2093
Tariq M Rana
Ya-Lin Chiu
P2860
P304
P356
10.1261/RNA.5103703
P407
P577
2003-09-01T00:00:00Z