pH-dependence and structure-activity relationships in the papain-catalysed hydrolysis of anilides.
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Consequences of molecular recognition in the S1-S2 intersubsite region of papain for catalytic-site chemistry. Change in pH-dependence characteristics and generation of an inverse solvent kinetic isotope effect by introduction of a P1-P2 amide bondSubstrate-derived two-protonic-state electrophiles as sensitive kinetic specificity probes for cysteine proteinases. Activation of 2-pyridyl disulphides by hydrogen-bondingThe structure and mechanism of stem bromelain. Evaluation of the homogeneity of purified stem bromelain, determination of the molecular weight and kinetic analysis of the bromelain-catalysed hydrolysis of N-benzyloxycarbonyl-L-phenylalanyl-L-serineInhibition of Escherichia coli CTP synthase by glutamate gamma-semialdehyde and the role of the allosteric effector GTP in glutamine hydrolysisTrimethyl lock: a stable chromogenic substrate for esterases.A ubiquitin-specific protease that efficiently cleaves the ubiquitin-proline bond.Identification of the functional ionic groups of papain by pH/rate profile analysis.The electrostatic fields in the active-site clefts of actinidin and papain.The specificity of the S1' subsite of papainReaction pathway and free energy profile for papain-catalyzed hydrolysis of N-acetyl-Phe-Gly 4-nitroanilide.Dependence of the P2-S2 stereochemical selectivity of papain on the nature of the catalytic-site chemistry. Quantification of selectivity in the catalysed hydrolysis of the enantiomeric N-acetylphenylalanylglycine 4-nitroanilides.Variation in the P2-S2 stereochemical selectivity towards the enantiomeric N-acetylphenylalanylglycine 4-nitroanilides among the cysteine proteinases papain, ficin and actinidin.The interplay of electrostatic and binding interactions determining active centre chemistry and catalytic activity in actinidin and papain.Chymopapain A. Purification and investigation by covalent chromatography and characterization by two-protonic-state reactivity-probe kinetics, steady-state kinetics and resonance Raman spectroscopy of some dithioacyl derivatives.Investigation of the active site of papain with fluorescent probes.Mercaptide-imidazolium ion-pair: the reactive nucleophile in papain catalysis.Protein immobilization to alumina supports: II. Papain immobilization to alumina via organophosphate linkers.A dithioamino acid in kinetic studies on trypsin catalysis. The tryptic S-alkyl cleavage of ethyl 6-ammoniumdithiohexanoate p-toluene sulfonate.
P2860
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P2860
pH-dependence and structure-activity relationships in the papain-catalysed hydrolysis of anilides.
description
1971 nî lūn-bûn
@nan
1971年の論文
@ja
1971年論文
@yue
1971年論文
@zh-hant
1971年論文
@zh-hk
1971年論文
@zh-mo
1971年論文
@zh-tw
1971年论文
@wuu
1971年论文
@zh
1971年论文
@zh-cn
name
pH-dependence and structure-ac ...... alysed hydrolysis of anilides.
@en
pH-dependence and structure-ac ...... alysed hydrolysis of anilides.
@nl
type
label
pH-dependence and structure-ac ...... alysed hydrolysis of anilides.
@en
pH-dependence and structure-ac ...... alysed hydrolysis of anilides.
@nl
prefLabel
pH-dependence and structure-ac ...... alysed hydrolysis of anilides.
@en
pH-dependence and structure-ac ...... alysed hydrolysis of anilides.
@nl
P2860
P356
P1433
P1476
pH-dependence and structure-ac ...... talysed hydrolysis of anilides
@en
P2093
P2860
P304
P356
10.1042/BJ1240117
P407
P50
P577
1971-08-01T00:00:00Z