Expression of ICOS in vivo defines CD4+ effector T cells with high inflammatory potential and a strong bias for secretion of interleukin 10.
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The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cellsThe immunomodulatory proteins B7-DC, B7-H2, and B7-H3 are differentially expressed across gestation in the human placentaEmerging mechanisms of immune regulation: the extended B7 family and regulatory T cellsICOS Co-Stimulation: Friend or Foe?Inducible costimulator expression regulates the magnitude of Th2-mediated airway inflammation by regulating the number of Th2 cellsRenal dendritic cells ameliorate nephrotoxic acute kidney injuryThe inducible T-cell co-stimulator molecule is expressed on subsets of T cells and is a new marker of lymphomas of T follicular helper cell-derivation.Yin-Yang of costimulation: crucial controls of immune tolerance and function.Anti-CTLA-4 treatment induces IL-10-producing ICOS+ regulatory T cells displaying IDO-dependent anti-inflammatory properties in a mouse model of colitis.Expression QTL mapping in regulatory and helper T cells from the BXD family of strains reveals novel cell-specific genes, gene-gene interactions and candidate genes for auto-immune disease.Modulation of surgical fibrosis by microbial zwitterionic polysaccharidesMolecular pathways in the induction of interleukin-27-driven regulatory type 1 cells.Genetic susceptibility to systemic lupus erythematosus protects against cerebral malaria in mice.Differences in allergen-induced T cell activation between allergic asthma and rhinitis: Role of CD28, ICOS and CTLA-4Expression and function of inducible co-stimulator in patients with systemic lupus erythematosus: possible involvement in excessive interferon-gamma and anti-double-stranded DNA antibody production.ICOS-expressing lymphocytes promote resolution of CD8-mediated lung injury in a mouse model of lung rejectionB7RP-1-ICOS interactions are required for optimal infection-induced expansion of CD4+ Th1 and Th2 responsesRole of T cell co-stimulation in murine models of allergic asthma.Innate lymphoid cells responding to IL-33 mediate airway hyperreactivity independently of adaptive immunity.Signaling pathways in Th2 development.Molecular and cellular pathogenesis of X-linked lymphoproliferative disease.The B7/CD28 costimulatory family in autoimmunity.Expression of XCR1 Characterizes the Batf3-Dependent Lineage of Dendritic Cells Capable of Antigen Cross-PresentationMemory CD4+ T-cell-mediated protection depends on secondary effectors that are distinct from and superior to primary effectors.Follicular B helper T cells in antibody responses and autoimmunity.Therapeutic potential of adenovirus as a vaccine vector for chronic virus infections.Establishment of memory for IL-10 expression in developing T helper 2 cells requires repetitive IL-4 costimulation and does not impair proliferation.Co-stimulatory molecules as potential targets for therapeutic intervention in allergic airway disease.The Costimulatory Molecule ICOS Regulates Host Th1 and Follicular Th Cell Differentiation in Response to Plasmodium chabaudi chabaudi AS Infection.The role of B7 family molecules in hematologic malignancyRenal dendritic cells stimulate IL-10 production and attenuate nephrotoxic nephritis.ICOS controls Foxp3(+) regulatory T-cell expansion, maintenance and IL-10 production during helminth infectionTransient blockade of the inducible costimulator pathway generates long-term tolerance to factor VIII after nonviral gene transfer into hemophilia A miceGenetic defects in common variable immunodeficiencyB7h (ICOS-L) maintains tolerance at the fetomaternal interfaceCTLA-4 blockade increases IFNgamma-producing CD4+ICOShi cells to shift the ratio of effector to regulatory T cells in cancer patients.Immunological decision-making: how does the immune system decide to mount a helper T-cell response?Targeting of the immune system in systemic lupus erythematosus.Suppression of T cell costimulator ICOS by Delta9-tetrahydrocannabinol.T-cell costimulation and coinhibition in atherosclerosis.
P2860
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P2860
Expression of ICOS in vivo defines CD4+ effector T cells with high inflammatory potential and a strong bias for secretion of interleukin 10.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Expression of ICOS in vivo def ...... r secretion of interleukin 10.
@en
Expression of ICOS in vivo def ...... r secretion of interleukin 10.
@nl
type
label
Expression of ICOS in vivo def ...... r secretion of interleukin 10.
@en
Expression of ICOS in vivo def ...... r secretion of interleukin 10.
@nl
prefLabel
Expression of ICOS in vivo def ...... r secretion of interleukin 10.
@en
Expression of ICOS in vivo def ...... r secretion of interleukin 10.
@nl
P2093
P2860
P356
P1476
Expression of ICOS in vivo def ...... r secretion of interleukin 10.
@en
P2093
Andreas Radbruch
Eckard Hamelmann
Hans Werner Mages
Kerstin Bonhagen
Max Löhning
Richard A Kroczek
Tilmann Kallinich
P2860
P304
P356
10.1084/JEM.20020632
P407
P577
2003-01-01T00:00:00Z