The role of cooperativity with Src in oncogenic transformation mediated by non-small cell lung cancer-associated EGF receptor mutants.
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Regulation of SRC family kinases in human cancersA comprehensive, multi-scale dynamical model of ErbB receptor signal transduction in human mammary epithelial cellsPareto Optimization Identifies Diverse Set of Phosphorylation Signatures Predicting Response to Treatment with Dasatinibc-Src associates with ErbB2 through an interaction between catalytic domains and confers enhanced transforming potential.Aberrant trafficking of NSCLC-associated EGFR mutants through the endocytic recycling pathway promotes interaction with Src.Epidermal Growth Factor Receptor Cell Proliferation Signaling PathwaysEGF receptor exposed to oxidative stress acquires abnormal phosphorylation and aberrant activated conformation that impairs canonical dimerizationJAK2/STAT3 targeted therapy suppresses tumor invasion via disruption of the EGFRvIII/JAK2/STAT3 axis and associated focal adhesion in EGFRvIII-expressing glioblastoma.Sorafenib activates CD95 and promotes autophagy and cell death via Src family kinases in gastrointestinal tumor cells.Phase II study of dasatinib in patients with advanced non-small-cell lung cancerA kinase inhibitor screen reveals protein kinase C-dependent endocytic recycling of ErbB2 in breast cancer cells.Lung injury and lung cancer caused by cigarette smoke-induced oxidative stress: Molecular mechanisms and therapeutic opportunities involving the ceramide-generating machinery and epidermal growth factor receptor.Phase I/II study of the Src inhibitor dasatinib in combination with erlotinib in advanced non-small-cell lung cancer.Nexus of signaling and endocytosis in oncogenesis driven by non-small cell lung cancer-associated epidermal growth factor receptor mutants.Molecular mechanisms of action and potential biomarkers of growth inhibition of dasatinib (BMS-354825) on hepatocellular carcinoma cells.Lung cancer and lung injury: the dual role of ceramideSrc mediates cigarette smoke-induced resistance to tyrosine kinase inhibitors in NSCLC cellsCigarette smoke induces aberrant EGF receptor activation that mediates lung cancer development and resistance to tyrosine kinase inhibitors.Potentiation of epidermal growth factor-mediated oncogenic transformation by sialidase NEU3 leading to Src activation.The cell surface glycoprotein CUB domain-containing protein 1 (CDCP1) contributes to epidermal growth factor receptor-mediated cell migrationReversine Induced Multinucleated Cells, Cell Apoptosis and Autophagy in Human Non-Small Cell Lung Cancer Cells.EGF-receptor specificity for phosphotyrosine-primed substrates provides signal integration with SrcEGFR Fusions as Novel Therapeutic Targets in Lung CancerInhibition of radiation-induced glioblastoma invasion by genetic and pharmacological targeting of MDA-9/Syntenin.Cellular functions regulated by phosphorylation of EGFR on Tyr845.Advances in EGFR as a Predictive Marker in Lung Adenocarcinoma.The TWEAK Receptor Fn14 Is an Src-Inducible Protein and a Positive Regulator of Src-Driven Cell Invasion.WZ4002, a third-generation EGFR inhibitor, can overcome anoikis resistance in EGFR-mutant lung adenocarcinomas more efficiently than Src inhibitors.AC-93253 iodide, a novel Src inhibitor, suppresses NSCLC progression by modulating multiple Src-related signaling pathways.Characterization of In Vivo Resistance to Osimertinib and JNJ-61186372, an EGFR/Met Bispecific Antibody, Reveals Unique and Consensus Mechanisms of Resistance.The E3 ubiquitin ligase NEDD4 mediates cell migration signaling of EGFR in lung cancer cells.Cytosolic PKM2 stabilizes mutant EGFR protein expression through regulating HSP90-EGFR association.Identification and characterization of proteins isolated from microvesicles derived from human lung cancer pleural effusions.
P2860
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P2860
The role of cooperativity with Src in oncogenic transformation mediated by non-small cell lung cancer-associated EGF receptor mutants.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
The role of cooperativity with ...... sociated EGF receptor mutants.
@en
The role of cooperativity with ...... sociated EGF receptor mutants.
@nl
type
label
The role of cooperativity with ...... sociated EGF receptor mutants.
@en
The role of cooperativity with ...... sociated EGF receptor mutants.
@nl
prefLabel
The role of cooperativity with ...... sociated EGF receptor mutants.
@en
The role of cooperativity with ...... sociated EGF receptor mutants.
@nl
P2093
P2860
P356
P1433
P1476
The role of cooperativity with ...... sociated EGF receptor mutants.
@en
P2093
P2860
P2888
P304
P356
10.1038/ONC.2009.31
P407
P577
2009-03-23T00:00:00Z
P5875
P6179
1052759860