Cell cycle-dependent role of MRN at dysfunctional telomeres: ATM signaling-dependent induction of nonhomologous end joining (NHEJ) in G1 and resection-mediated inhibition of NHEJ in G2
about
Five dysfunctional telomeres predict onset of senescence in human cellsHuman UPF1 interacts with TPP1 and telomerase and sustains telomere leading-strand replicationShelterin complex and associated factors at human telomeres53BP1: pro choice in DNA repairApollo contributes to G overhang maintenance and protects leading-end telomeresDNA-damage response and repair activities at uncapped telomeres depend on RNF8Single strand DNA binding proteins 1 and 2 protect newly replicated telomeresSNMIB/Apollo protects leading-strand telomeres against NHEJ-mediated repairThe DNA structure and sequence preferences of WRN underlie its function in telomeric recombination eventsRole of 53BP1 oligomerization in regulating double-strand break repair.How telomeres solve the end-protection problem.Telomeres: protecting chromosomes against genome instabilityStrand exchange of telomeric DNA catalyzed by the Werner syndrome protein (WRN) is specifically stimulated by TRF2ATR contributes to telomere maintenance in human cellsCrosstalk between telomere maintenance and radiation effects: A key player in the process of radiation-induced carcinogenesis.The MRN complex in double-strand break repair and telomere maintenance.DNA double-strand break signaling and human disorders.NBS1 plays a synergistic role with telomerase in the maintenance of telomeres in Arabidopsis thaliana.Mre11-Rad50-Nbs1 conformations and the control of sensing, signaling, and effector responses at DNA double-strand breaksThe role of ATM in the deficiency in nonhomologous end-joining near telomeres in a human cancer cell line.The role of double-strand break repair pathways at functional and dysfunctional telomeres.BRCA1 and CtIP promote alternative non-homologous end-joining at uncapped telomeres53BP1 mediates the fusion of mammalian telomeres rendered dysfunctional by DNA-PKcs loss or inhibition.Identification and characterization of a novel gene encoding the NBS1 protein in Pyricularia oryzae.Maintaining the end: roles of telomere proteins in end-protection, telomere replication and length regulationEarly and late steps in telomere overhang processing in normal human cells: the position of the final RNA primer drives telomere shorteningCritical role of the POT1 OB domain in maintaining genomic stability.Distinct DNA damage determines differential phosphorylation of Chk2.PHF11 promotes DSB resection, ATR signaling, and HR.NBS1 Phosphorylation Status Dictates Repair Choice of Dysfunctional Telomeres.Processing by MRE11 is involved in the sensitivity of subtelomeric regions to DNA double-strand breaks.Hypothesis: Paralog Formation from Progenitor Proteins and Paralog Mutagenesis Spur the Rapid Evolution of Telomere Binding Proteins.DNA repair at telomeres: keeping the ends intact.The shelterin complex and hematopoiesis.p16(INK4a) protects against dysfunctional telomere-induced ATR-dependent DNA damage responses.Biological complexities in radiation carcinogenesis and cancer radiotherapy: impact of new biological paradigms.The MRE11 complex: starting from the ends.Stem cell expansion during carcinogenesis in stem cell-depleted conditional telomeric repeat factor 2 null mutant mice.Assembly of checkpoint and repair machineries at DNA damage sites.Stop pulling my strings - what telomeres taught us about the DNA damage response.
P2860
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P2860
Cell cycle-dependent role of MRN at dysfunctional telomeres: ATM signaling-dependent induction of nonhomologous end joining (NHEJ) in G1 and resection-mediated inhibition of NHEJ in G2
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
Cell cycle-dependent role of M ...... iated inhibition of NHEJ in G2
@en
Cell cycle-dependent role of M ...... n of nonhomologous end joining
@nl
type
label
Cell cycle-dependent role of M ...... iated inhibition of NHEJ in G2
@en
Cell cycle-dependent role of M ...... n of nonhomologous end joining
@nl
prefLabel
Cell cycle-dependent role of M ...... iated inhibition of NHEJ in G2
@en
Cell cycle-dependent role of M ...... n of nonhomologous end joining
@nl
P2860
P356
P1476
Cell cycle-dependent role of M ...... iated inhibition of NHEJ in G2
@en
P2093
Nadya Dimitrova
P2860
P304
P356
10.1128/MCB.00476-09
P407
P577
2009-08-10T00:00:00Z