Identification of the Zn2+ binding site and mode of operation of a mammalian Zn2+ transporter.
about
The Critical Roles of Zinc: Beyond Impact on Myocardial SignalingStructural basis for autoregulation of the zinc transporter YiiPCompound heterozygous mutations in SLC30A2/ZnT2 results in low milk zinc concentrations: a novel mechanism for zinc deficiency in a breast-fed infantSLC30A10 is a cell surface-localized manganese efflux transporter, and parkinsonism-causing mutations block its intracellular trafficking and efflux activityZn2+ efflux through lysosomal exocytosis prevents Zn2+-induced toxicity.Demand for Zn2+ in acid-secreting gastric mucosa and its requirement for intracellular Ca2+.Differential subcellular localization of the splice variants of the zinc transporter ZnT5 is dictated by the different C-terminal regionsProton-dependent zinc release from intracellular ligandsmiR-183-96-182 cluster is overexpressed in prostate tissue and regulates zinc homeostasis in prostate cellsProlactin (PRL)-stimulated ubiquitination of ZnT2 mediates a transient increase in zinc secretion followed by ZnT2 degradation in mammary epithelial cells.Selective electrodiffusion of zinc ions in a Zrt-, Irt-like protein, ZIPB.Slc39a7/zip7 plays a critical role in development and zinc homeostasis in zebrafish.Functional analysis of two single nucleotide polymorphisms in SLC30A2 (ZnT2): implications for mammary gland function and breast disease in womenAdvances in the molecular understanding of biological zinc transport.Physiological roles of zinc transporters: molecular and genetic importance in zinc homeostasis.Cytosolic zinc release and clearance in hippocampal neurons exposed to glutamate--the role of pH and sodium.ZnT2 is a critical mediator of lysosomal-mediated cell death during early mammary gland involution.Cooperative functions of ZnT1, metallothionein and ZnT4 in the cytoplasm are required for full activation of TNAP in the early secretory pathwayZnT-1 extrudes zinc from mammalian cells functioning as a Zn(2+)/H(+) exchanger.Redox regulation of intracellular zinc: molecular signaling in the life and death of neuronsMutations in SLC30A10 cause parkinsonism and dystonia with hypermanganesemia, polycythemia, and chronic liver disease.Cytosolic acidification and intracellular zinc release in hippocampal neuronsHistidine pairing at the metal transport site of mammalian ZnT transporters controls Zn2+ over Cd2+ selectivity.Transcriptional regulation of the Zrg17 zinc transporter of the yeast secretory pathway.In situ dimerization of multiple wild type and mutant zinc transporters in live cells using bimolecular fluorescence complementation.Molecular and genetic features of zinc transporters in physiology and pathogenesis.Zinc homeostasis and signaling in glia.Zinc and myocardial ischemia/reperfusion injury.The biology of zinc transport in mammary epithelial cells: implications for mammary gland development, lactation, and involution.Current understanding of ZIP and ZnT zinc transporters in human health and diseases.Relationship between the architecture of zinc coordination and zinc binding affinity in proteins--insights into zinc regulation.Cation Diffusion Facilitator family: Structure and function.The Physiological, Biochemical, and Molecular Roles of Zinc Transporters in Zinc Homeostasis and Metabolism.Tissue nonspecific alkaline phosphatase is activated via a two-step mechanism by zinc transport complexes in the early secretory pathwayThe contribution of zinc to platelet behaviour during haemostasis and thrombosis.Dissecting the Process of Activation of Cancer-promoting Zinc-requiring Ectoenzymes by Zinc Metalation Mediated by ZNT Transporters.Newport Green, a fluorescent sensor of weakly bound cellular Zn(2+): competition with proteome for Zn(2)The PP-motif in luminal loop 2 of ZnT transporters plays a pivotal role in TNAP activationDirect Comparison of Manganese Detoxification/Efflux Proteins and Molecular Characterization of ZnT10 Protein as a Manganese Transporter.TNFα Post-Translationally Targets ZnT2 to Accumulate Zinc in Lysosomes.
P2860
Q26786789-01ED6304-BD1C-45C2-BCED-AE4B27703A85Q27657426-094FAFF6-16FB-4FF9-9CE3-7E6064403F9FQ28533518-68A00E74-8E6C-4E1C-A920-E5842121D1E2Q28910400-A43FB3F2-44ED-4A0B-AACB-F4E64F6A872DQ33893336-CB2DD900-E806-447B-B338-4A8FA3D7E09FQ33941224-DABC35F4-54E7-4CB5-98C1-73AC7C6F69D0Q34009669-5FE5C1D2-BEAA-4AE0-BDEB-2AA4304C53EAQ34034443-4DAF1C38-A50F-4162-BCAC-22B02F52DDD4Q34064071-22920C6C-C3E7-41A1-843A-171E662AFEA2Q34141011-8E6BFE6D-4D18-43F4-8ED9-27DF1CA9F4D0Q34386009-ED955B8D-408F-4588-B1EB-890B01CA8494Q34389084-43D6DAA0-8BF9-4E97-884E-861BE488D294Q34432762-358913DB-2622-48B9-ABC1-E3B1D8CDD363Q34459994-A2FE9E81-0384-4050-9A13-63AB38B01903Q34550179-6F011405-CE90-46F0-B089-7DB0185E2A72Q34793709-1C663097-3EBF-403E-A63C-D252EDC69C8CQ35011972-2674B816-8B0C-4904-A5D2-0B8BE21F39B4Q35035248-CB391D94-205A-4A60-AE75-5CAE1AA7F233Q35192472-25BC2850-FB3B-4C78-B3A2-D93DA3FF3037Q35193898-6C78549F-F323-4206-AA9D-5A5320BDC4A5Q35843237-08A8EF3E-796A-4EDE-9F53-BC68526BC2E2Q35881777-C836B8D9-BB2D-41D4-9065-519A1E7CC277Q35982954-A1C86A82-3299-4117-87D7-91079E014EC2Q36719745-91601A41-148A-4943-B79A-466ABD05E42CQ37635752-2F5F130C-A9D7-49AD-80CF-AC699348ADBEQ37874950-906D404E-B8CA-4E5E-A5DD-A275C72699E2Q37983518-94B01E85-0CA7-4539-965B-07968C8CA097Q38132061-24D12271-3A2F-4DED-930D-AE759480BB21Q38171347-B8330D70-2FB6-4C50-A49F-D3F475754505Q38202894-4960D469-5BA7-4A44-BDCA-91E65452C4D5Q38254214-FF570C7E-FBB0-47C7-AF11-941F89D46F0AQ38431694-37050780-9E9C-4C19-87D8-0C0B89DFCA2CQ38530500-3091F6C8-D151-442C-BEF4-B3D877BB8C3EQ38569070-221497CA-F58D-4629-896B-6DA69FB036FAQ38685836-78B8F190-AF1E-4761-9290-556BA573CF25Q38724045-3CDEA1CC-9584-4836-A34C-34449B3DF0EAQ38762931-81E928F3-CD84-4E1E-B194-B8AFF3853BEDQ38764363-90EEC181-0088-4C47-A644-C231C48D02B6Q38768341-6B6C02C4-CC39-4A13-8FB6-84208F09FEE5Q38895246-03CA62F8-8B15-429D-961A-826DA3ADE214
P2860
Identification of the Zn2+ binding site and mode of operation of a mammalian Zn2+ transporter.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
Identification of the Zn2+ bin ...... a mammalian Zn2+ transporter.
@en
Identification of the Zn2+ bin ...... a mammalian Zn2+ transporter.
@nl
type
label
Identification of the Zn2+ bin ...... a mammalian Zn2+ transporter.
@en
Identification of the Zn2+ bin ...... a mammalian Zn2+ transporter.
@nl
prefLabel
Identification of the Zn2+ bin ...... a mammalian Zn2+ transporter.
@en
Identification of the Zn2+ bin ...... a mammalian Zn2+ transporter.
@nl
P2093
P2860
P356
P1476
Identification of the Zn2+ bin ...... a mammalian Zn2+ transporter.
@en
P2093
Chen Keasar
Ehud Ohana
Eitan Hoch
Israel Sekler
Michal Hershfinkel
Ofer Yifrach
Taiho Kambe
P2860
P304
17677-17686
P356
10.1074/JBC.M109.007203
P407
P577
2009-04-14T00:00:00Z